There are 7 ways to get from Des Moines to Middleburg by plane, taxi, bus (Flixbus, Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Gainesville Regional Airport, taxi
best- Fly from Des Moines (DSM) to Gainesville Regional Airport (GNV)DSM - GNV
- Take the taxi from Gainesville-Airport-GNV to Middleburg
5h 53m$388–1,401Bus
cheapest- Take the bus from Des Moines to Burlington
- Take the bus from Burlington to St Louis
- Take the bus from St Louis Bus Station to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Jacksonville
30h 31m$193–503Bus, train, taxi
- Take the bus from Des Moines to Burlington
- Take the bus from Burlington to Galesburg
- Take the train from Galesburg Amtrak Station to Chicago Union Station
- Take the train from Chicago Union Station to Jacksonville
- Take the taxi from Jacksonville to Middleburg
45h 19m$415–1,607Drive 1,221.2 mi
- Drive from Des Moines to Middleburg1,221.2 mi
21h 20m$223–322Fly to Jacksonville, bus, line 900 bus
- Fly from Des Moines (DSM) to Jacksonville (JAX)DSM - JAX
- Take the bus from JRTC Bay P to Blanding Blvd + Orange Park Northway
- Take the bus from Blanding Blvd + Orange Park Northway to Circle K
7h 11m$221–1,030Fly to Orlando Sanford, drive
- Fly from Des Moines (DSM) to Orlando Sanford (SFB)DSM - SFB
- Drive from Orlando-Sanford-Airport-SFB to Middleburg
5h 41m$199–806Bus, train
- Take the bus from Des Moines to ChicagoDes Moines
- Take the train from Chicago Union Station to JacksonvilleFloridian
47h$309–1,463
Des Moines to Middleburg by bus
Questions & Answers
The cheapest way to get from Des Moines to Middleburg is to drive which costs $220 - $330 and takes 21h 20m.
The fastest way to get from Des Moines to Middleburg is to fly and drive which takes 5h 41m and costs $190 - $850.
No, there is no direct bus from Des Moines to Middleburg. However, there are services departing from Des Moines and arriving at Circle K via Burlington, St Louis Bus Station, Atlanta Bus Station, JRTC Bay P and Blanding Blvd + Orange Park Northway. The journey, including transfers, takes approximately 30h 31m.
The distance between Des Moines and Middleburg is 1091 miles. The road distance is 1228.4 miles.
The best way to get from Des Moines to Middleburg without a car is to bus which takes 30h 31m and costs $190 - $550.
It takes approximately 5h 53m to get from Des Moines to Middleburg, including transfers.
Des Moines to Middleburg bus services, operated by Burlington Trailways, depart from Des Moines station.
Des Moines to Middleburg bus services, operated by Burlington Trailways, arrive at Burlington station.
Middleburg is 1h ahead of Des Moines. It is currently 1:10 AM in Des Moines and 2:10 AM in Middleburg.
Yes, the driving distance between Des Moines to Middleburg is 1228 miles. It takes approximately 21h 20m to drive from Des Moines to Middleburg.
What companies run services between Des Moines, IA, USA and Middleburg, FL, USA?
You can take a bus from Des Moines to Circle K via Burlington, St Louis Bus Station, Atlanta Bus Station, Jacksonville, JRTC Bay P, and Blanding Blvd + Orange Park Northway in around 30h 31m.
- Website
- allegiantair.com
Flights from Des Moines to Jacksonville
- Ave. Duration
- 2h 29m
- When
- Thursday
- Estimated price
- $200–1,000
Flights from Des Moines to Orlando Sanford
- Ave. Duration
- 2h 49m
- When
- Every day
- Estimated price
- $160–750
- Website
- aa.com
Flights from Des Moines to Gainesville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 46m
- When
- Every day
- Estimated price
- $300–1,400
Flights from Des Moines to Gainesville Regional Airport via Charlotte
- Ave. Duration
- 7h 31m
- When
- Every day
- Estimated price
- $260–1,200
Flights from Des Moines to Jacksonville via Chicago O'Hare
- Ave. Duration
- 5h 31m
- When
- Monday, Tuesday, Wednesday, and Friday
- Estimated price
- $220–1,100
- Website
- delta.com
Flights from Des Moines to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Des Moines to Jacksonville via Atlanta
- Ave. Duration
- 4h 47m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $200–1,000
- Website
- southwest.com
Flights from Des Moines to Jacksonville via St. Louis
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,000
- Website
- united.com
Flights from Des Moines to Jacksonville via Chicago O'Hare
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $220–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $24–85
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Jacksonville
- Ave. Duration
- 34h 45m
- Frequency
- Once daily
- Estimated price
- $250–1,300
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Des Moines to Burlington
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
Bus from Burlington to St Louis
- Ave. Duration
- 4h 30m
- Frequency
- Once daily
- Estimated price
- $50–128
- Website
- https://burlingtontrailways.com
- Saver Fares
- $50–75
- Flexible Fares
- $70–100
- Saver Fare
- $92
- Flex Fare
- $128
Bus from Burlington to Galesburg
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- $25–50
- Website
- https://burlingtontrailways.com
- Saver Fares
- $25–40
- Flexible Fares
- $30–50
Bus from Des Moines to Chicago
- Ave. Duration
- 7h 15m
- Frequency
- Twice daily
- Estimated price
- $55–160
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–100
- Flexible Fares
- $90–140
- Saver Fare
- $55–110
- Flex Fare
- $75–160
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 30m
- Frequency
- Once daily
- Estimated price
- $55–150
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Jacksonville
- Ave. Duration
- 6h 35m
- Frequency
- 3 times a day
- Estimated price
- $50–140
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Atlanta Bus Station to Jacksonville
- Ave. Duration
- 9h 15m
- Frequency
- Once daily
- Estimated price
- $45–120
- Website
- https://www.greyhound.com/
- Phone
- +1 904-630-3100
- Website
- jtafla.com
Bus from JRTC Bay P to Blanding Blvd + Orange Park Northway
- Ave. Duration
- 48 min
- Frequency
- Every 20 minutes
- Estimated price
- $1–3
- Website
- https://www.jtafla.com
Bus from Blanding Blvd + Orange Park Northway to Circle K
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $1–3
- Website
- https://www.jtafla.com
- Ave. Duration
- 47 min
- Estimated price
- $75–180
Gainesville Cab Co.
- Phone
- +1 352-371-1515
- Website
- gainesvillemarooncab.com
Cabs 24HR
- Phone
- +1 855-374-8484
- Website
- cab24hr.com
zTrip
- Phone
- +1 904-222-2222
- Website
- ztrip.com
ABC Taxi
- Phone
- +1 904-554-5564
- Website
- abctaxijax.com
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