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How to get fromDes Moines to Middleburgby plane, taxi, bus (Greyhound, Flixbus), bus, train or car

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There are 5 ways to get from Des Moines to Middleburg by plane, taxi, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gainesville Regional Airport, taxi

    best
    1. Fly from Des Moines (DSM) to Gainesville Regional Airport (GNV)plane plane DSM - GNV
    2. Take the taxi from Gainesville-Airport-GNV to Middleburgtaxi taxi
    5h 27m
    $318–1,001
  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    33h 1m
    $164–328
  3. Bus, train, taxi

    1. Take the bus from Des Moines to Iowa Citybus bus
    2. Take the bus from Iowa City to Chicago Bus Stationbus bus
    3. Take the train from Chicago Union Station to Jacksonvilletrain train
    4. Take the taxi from Jacksonville to Middleburgtaxi taxi
    44h 24m
    $339–602
  4. Drive 1,221.2 mi

    1. Drive from Des Moines to Middleburgcar car 1,221.2 mi
    21h 30m
    $223–322
  5. Fly to Jacksonville, bus, line 900 bus

    1. Fly from Des Moines (DSM) to Jacksonville (JAX)plane plane DSM - JAX
    2. Take the bus from JRTC Bay P to Blanding Blvd + Orange Park Northwaybus bus
    3. Take the bus from Blanding Blvd + Orange Park Northway to Circle Kbus bus
    7h 11m
    $231–1,130

Des Moines to Middleburg by bus

Calendar15Weekly Buses
Duration33h 1mAverage Duration
Ticket$164Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Middleburg, FL, USA?

You can take a bus from Des Moines to Circle K via Chicago Bus Station, Atlanta Bus Station, Jacksonville, JRTC Bay P, and Blanding Blvd + Orange Park Northway in around 33h 1m.

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