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How to get fromDes Moines to Middleburgby plane, taxi, bus (Flixbus, Greyhound), bus, train or car

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There are 7 ways to get from Des Moines to Middleburg by plane, taxi, bus (Flixbus, Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gainesville Regional Airport, taxi

    best
    1. Fly from Des Moines (DSM) to Gainesville Regional Airport (GNV)planeDSM - GNV
    2. Take the taxi from Gainesville-Airport-GNV to Middleburgtaxi
    5h 53m
    $388–1,401
  2. Bus

    cheapest
    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to St Louisbus
    3. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
    4. Take the bus from Atlanta Bus Station to Jacksonvillebus
    30h 31m
    $193–503
  3. Bus, train, taxi

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to Galesburgbus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
    4. Take the train from Chicago Union Station to Jacksonvilletrain
    5. Take the taxi from Jacksonville to Middleburgtaxi
    45h 19m
    $415–1,607
  4. Drive 1,221.2 mi

    1. Drive from Des Moines to Middleburgcar1,221.2 mi
    21h 20m
    $223–322
  5. Fly to Jacksonville, bus, line 900 bus

    1. Fly from Des Moines (DSM) to Jacksonville (JAX)planeDSM - JAX
    2. Take the bus from JRTC Bay P to Blanding Blvd + Orange Park Northwaybus
    3. Take the bus from Blanding Blvd + Orange Park Northway to Circle Kbus
    7h 11m
    $221–1,030
  6. Fly to Orlando Sanford, drive

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)planeDSM - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Middleburgcar
    5h 41m
    $199–806
  7. Bus, train

    1. Take the bus from Des Moines to ChicagobusDes Moines
    2. Take the train from Chicago Union Station to JacksonvilletrainFloridian
    47h
    $309–1,463

Des Moines to Middleburg by bus

Calendar7Weekly Buses
Duration30h 31mAverage Duration
Ticket$193Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Middleburg, FL, USA?

You can take a bus from Des Moines to Circle K via Burlington, St Louis Bus Station, Atlanta Bus Station, Jacksonville, JRTC Bay P, and Blanding Blvd + Orange Park Northway in around 30h 31m.

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