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How to get fromDes Moines to Manhattanby plane, bus (Greyhound, Flixbus), bus, train or car

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There are 7 ways to get from Des Moines to Manhattan by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Laguardia Airport

    best
    1. Fly from Des Moines (DSM) to Laguardia Airport (LGA)plane plane DSM - LGA
    3h 36m
    $151–724
  2. Bus

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the bus from Chicago Bus Station to New York Midtownbus bus FlixBus N2640
    28h 15m
    $136–315
  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train Lake Shore Limited / ...
    28h 26m
    $151–425
  4. Drive 1,108.7 mi

    1. Drive from Des Moines to Manhattancar car 1,108.7 mi
    18h 30m
    $203–293
  5. Fly to Newark Liberty International Airport

    1. Fly from Des Moines (DSM) to Newark Liberty International Airport (EWR)plane plane DSM - EWR
    3h 28m
    $158–699
  6. Fly to John F. Kennedy International Airport

    1. Fly from Des Moines (DSM) to John F. Kennedy International Airport (JFK)plane plane DSM - JFK
    5h 48m
    $171–789
  7. Fly to Philadelphia International Airport, train

    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane plane DSM - PHL
    2. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4h 51m
    $190–1,471

Des Moines to Manhattan by bus

Calendar7Weekly Buses
Duration28h 15mAverage Duration
Ticket$136Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Manhattan, NY, USA?

American Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Laguardia Airport (LGA) every 2 hours. Alternatively, you can take a bus from Des Moines to New York Midtown via Chicago Bus Station in around 28h 15m.

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