There are 7 ways to get from Des Moines to Manhattan by plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Laguardia Airport
best- Fly from Des Moines (DSM) to Laguardia Airport (LGA)plane DSM - LGA
3h 36m$151–724Bus
cheapest- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
- Take the bus from Chicago Bus Station to New York Midtownbus FlixBus N2640
28h 15m$136–315Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
- Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain Lake Shore Limited / ...
28h 26m$151–425Drive 1,108.7 mi
- Drive from Des Moines to Manhattancar 1,108.7 mi
18h 30m$203–293Fly to Newark Liberty International Airport
- Fly from Des Moines (DSM) to Newark Liberty International Airport (EWR)plane DSM - EWR
3h 28m$158–699Fly to John F. Kennedy International Airport
- Fly from Des Moines (DSM) to John F. Kennedy International Airport (JFK)plane DSM - JFK
5h 48m$171–789Fly to Philadelphia International Airport, train
- Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane DSM - PHL
- Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain
4h 51m$190–1,471
Des Moines to Manhattan by bus
Questions & Answers
The cheapest way to get from Des Moines to Manhattan is to bus which costs $130 - $320 and takes 28h 15m.
The fastest way to get from Des Moines to Manhattan is to fly which takes 3h 28m and costs $150 - $700.
No, there is no direct bus from Des Moines to Manhattan. However, there are services departing from Des Moines and arriving at New York Midtown via Chicago Bus Station. The journey, including transfers, takes approximately 28h 15m.
The distance between Des Moines and Manhattan is 1049 miles. The road distance is 1115.2 miles.
The best way to get from Des Moines to Manhattan without a car is to bus which takes 28h 15m and costs $130 - $320.
It takes approximately 3h 36m to get from Des Moines to Manhattan, including transfers.
Des Moines to Manhattan bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Manhattan is to fly which takes 3h 36m and costs $150 - $750. Alternatively, you can bus, which costs $130 - $320 and takes 28h 15m.
Des Moines to Manhattan bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Manhattan is 1h ahead of Des Moines. It is currently 8:52 AM in Des Moines and 9:52 AM in Manhattan.
What companies run services between Des Moines, IA, USA and Manhattan, NY, USA?
American Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Laguardia Airport (LGA) every 2 hours. Alternatively, you can take a bus from Des Moines to New York Midtown via Chicago Bus Station in around 28h 15m.
- Website
- aa.com
Flights from Des Moines to Laguardia Airport
- Ave. Duration
- 2h 47m
- When
- Monday to Friday
- Estimated price
- $130–700
Flights from Des Moines to Laguardia Airport via Reagan Washington
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $140–750
Flights from Des Moines to Laguardia Airport via Chicago O'Hare
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $130–700
Flights from Des Moines to Newark Liberty International Airport via Chicago O'Hare
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to John F. Kennedy International Airport via Reagan Washington
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $140–750
Flights from Des Moines to John F. Kennedy International Airport via Charlotte
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $160–800
Flights from Des Moines to John F. Kennedy International Airport via Chicago O'Hare
- Ave. Duration
- 6h 53m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Des Moines to Philadelphia International Airport
- Ave. Duration
- 2h 41m
- When
- Every day
- Estimated price
- $160–850
Flights from Des Moines to Philadelphia International Airport via Chicago O'Hare
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $160–850
- Website
- delta.com
Flights from Des Moines to Laguardia Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- $130–700
Flights from Des Moines to Laguardia Airport via Detroit
- Ave. Duration
- 4h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–700
Flights from Des Moines to Laguardia Airport via Minneapolis
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $150–750
Flights from Des Moines to Newark Liberty International Airport via Detroit
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to John F. Kennedy International Airport via Minneapolis
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $160–800
Flights from Des Moines to John F. Kennedy International Airport via Detroit
- Ave. Duration
- 5h 20m
- When
- Tuesday and Wednesday
- Estimated price
- $140–750
Flights from Des Moines to Philadelphia International Airport via Detroit
- Ave. Duration
- 4h 46m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
- Website
- united.com
Flights from Des Moines to Laguardia Airport via Chicago O'Hare
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $130–700
Flights from Des Moines to Newark Liberty International Airport via Chicago O'Hare
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to Philadelphia International Airport via Chicago O'Hare
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $160–850
- Website
- southwest.com
Flights from Des Moines to Laguardia Airport via Chicago Midway
- Ave. Duration
- 5h
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–700
Flights from Des Moines to Laguardia Airport via St. Louis
- Ave. Duration
- 5h 35m
- When
- Sunday
- Estimated price
- $140–750
Flights from Des Moines to Philadelphia International Airport via St. Louis
- Ave. Duration
- 4h 40m
- When
- Sunday
- Estimated price
- $170–900
- Website
- allegiantair.com
Flights from Des Moines to Newark Liberty International Airport
- Ave. Duration
- 2h 30m
- When
- Monday and Friday
- Estimated price
- $120–650
Flights from Des Moines to Philadelphia International Airport
- Ave. Duration
- 2h 16m
- When
- Thursday
- Estimated price
- $160–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 20h 12m
- Frequency
- Once daily
- Estimated price
- $110–340
- Website
- https://www.amtrak.com/home.html
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $18–250
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 26m
- Frequency
- Hourly
- Estimated price
- $12–230
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $12–230
- Business Class
- $60–270
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from 30th Street Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 1h 20m
- Frequency
- Every 2 hours
- Estimated price
- $20–600
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $20–460
- First Class
- $130–600
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to New York Midtown
- Ave. Duration
- 20h 10m
- Frequency
- Once daily
- Estimated price
- $95–230
- Schedules at
- flixbus.com
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More Questions & Answers
Yes, the driving distance between Des Moines to Manhattan is 1115 miles. It takes approximately 18h 30m to drive from Des Moines to Manhattan.
Book your Des Moines to Manhattan bus tickets online with Omio and FlixBus.
There are 1050+ hotels available in Manhattan.







