There are 6 ways to get from Des Moines to Madison by plane, bus (Greyhound, Flixbus), car, bus, bus (Greyhound), or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Dane County Regional Airport-Truax Field
best- Fly from Des Moines (DSM) to Dane County Regional Airport-Truax Field (MSN)plane DSM - MSN
4h 36m$120–673Drive 274.9 mi
cheapest- Drive from Des Moines to Madisoncar 274.9 mi
5h 5m$51–73Bus
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123S / ...
- Take the bus from Chicago Bus Station to Madisonbus FlixBus 2514 / ...
11h 25m$73–138Fly to General Mitchell International Airport, bus
- Fly from Des Moines (DSM) to General Mitchell International Airport (MKE)plane DSM - MKE
- Take the bus from Mitchell Airport to Madison, WI-Lake St.bus
6h 34m$149–840Bus via Chicago
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123S / ...
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus Van Galder
11h 50m$75–148Bus via Saint Paul
- Take the bus from Des Moines to St. Paulbus Jefferson 802
- Take the bus from St. Paul to UW-Madisonbus Minneapolis / ...
12h 5m$100–155
Des Moines to Madison by bus
Questions & Answers
The cheapest way to get from Des Moines to Madison is to drive which costs $50 - $75 and takes 5h 5m.
The fastest way to get from Des Moines to Madison is to fly which takes 4h 36m and costs $120 - $700.
No, there is no direct bus from Des Moines to Madison. However, there are services departing from Des Moines and arriving at Madison via Chicago Bus Station. The journey, including transfers, takes approximately 11h 25m.
The distance between Des Moines and Madison is 261 miles. The road distance is 276.5 miles.
The best way to get from Des Moines to Madison without a car is to bus which takes 11h 25m and costs $70 - $140.
It takes approximately 4h 36m to get from Des Moines to Madison, including transfers.
Des Moines to Madison bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Madison is to fly which takes 4h 36m and costs $120 - $700. Alternatively, you can bus, which costs $70 - $140 and takes 11h 25m.
Des Moines to Madison bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Des Moines to Madison is 277 miles. It takes approximately 5h 5m to drive from Des Moines to Madison.
What companies run services between Des Moines, IA, USA and Madison, WI, USA?
United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to Dane County Regional Airport-Truax Field (MSN) hourly. Alternatively, you can take a bus from Des Moines to Madison via Chicago Bus Station in around 11h 25m.
- Website
- delta.com
Flights from Des Moines to Dane County Regional Airport-Truax Field via Minneapolis
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $100–650
Flights from Des Moines to Dane County Regional Airport-Truax Field via Detroit
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $150–800
Flights from Des Moines to Dane County Regional Airport-Truax Field via Atlanta
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Des Moines to General Mitchell International Airport via Minneapolis
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $140–900
Flights from Des Moines to General Mitchell International Airport via Atlanta
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $290–1,400
Flights from Des Moines to General Mitchell International Airport via Detroit
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $180–1,000
- Website
- aa.com
Flights from Des Moines to Dane County Regional Airport-Truax Field via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $100–650
Flights from Des Moines to Dane County Regional Airport-Truax Field via Dallas/Ft.Worth
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Des Moines to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $120–800
Flights from Des Moines to General Mitchell International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 59m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $300–1,400
- Website
- united.com
Flights from Des Moines to Dane County Regional Airport-Truax Field via Chicago O'Hare
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $100–650
Flights from Des Moines to Dane County Regional Airport-Truax Field via Denver
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Des Moines to General Mitchell International Airport via Chicago O'Hare
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $120–800
- Website
- southwest.com
Flights from Des Moines to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 4h 32m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–800
Flights from Des Moines to General Mitchell International Airport via Denver
- Ave. Duration
- 7h
- When
- Saturday
- Estimated price
- $300–1,400
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Chicago Bus Station to Madison
- Ave. Duration
- 3h 20m
- Frequency
- 3 times a day
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Bus from Mitchell Airport to Madison, WI-Lake St.
- Ave. Duration
- 2h 5m
- Frequency
- Twice daily
- Estimated price
- $11–19
- Schedules at
- flixbus.com
Bus from St. Paul to UW-Madison
- Ave. Duration
- 4h 55m
- Frequency
- Twice daily
- Estimated price
- $35–65
- Schedules at
- flixbus.com
- Phone
- +1 414-266-4409
- ticketinfo@badgerbus.com
- Website
- badgerbus.com
Bus from Mitchell Airport to Madison, WI-Lake St.
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- $24–35
- Website
- https://badgerbus.com
- Phone
- +1 608-752-5407
- vangalder@coachusa.com
- Website
- coachusa.com
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 50m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- https://www.coachusa.com/van-galder-bus-company
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $65–90
- Book at
- https://www.jeffersonlines.com
- Adult
- $65–90
Bus from St. Paul to UW-Madison
- Ave. Duration
- 6h 15m
- Frequency
- 3 times a day
- Estimated price
- $70–110
- Book at
- https://www.jeffersonlines.com
- Adult
- $70–110
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