There are 7 ways to get from Des Moines to Madison by plane, bus (Flixbus), car, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Dane County Regional Airport-Truax Field
best- Fly from Des Moines (DSM) to Dane County Regional Airport-Truax Field (MSN)plane DSM - MSN
4h 31m$180–1,123Bus
cheapest- Take the bus from Des Moines to St. Paulbus Jefferson 802
- Take the bus from Saint Paul Union Depot to Madisonbus FlixBus 2548
10h 45m$48–214Drive 274.9 mi
- Drive from Des Moines to Madisoncar 274.9 mi
5h 4m$51–73Fly to General Mitchell International Airport, bus
- Fly from Des Moines (DSM) to General Mitchell International Airport (MKE)plane DSM - MKE
- Take the bus from Mitchell Airport to Madison, WI-Lake St.bus
7h 10m$209–1,176Fly to Chicago O'Hare International Airport, bus
- Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane DSM - ORD
- Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus
5h 51m$153–536Bus via Burnsville
- Take the bus from Des Moines to Burnsvillebus Jefferson 802 / ...
- Take the bus from Mall of America - IKEA - Bloomington to Madison, WI-Lake St.bus Minneapolis
11h 36m$81–184Bus #2
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus Van Galder
11h 50m$63–126
Des Moines to Madison by bus
Questions & Answers
The cheapest way to get from Des Moines to Madison is to drive which costs $50 - $75 and takes 5h 4m.
The fastest way to get from Des Moines to Madison is to fly which takes 4h 31m and costs $180 - $1,200.
No, there is no direct bus from Des Moines to Madison. However, there are services departing from Des Moines and arriving at Madison via Saint Paul Union Depot. The journey, including transfers, takes approximately 10h 45m.
The distance between Des Moines and Madison is 261 miles. The road distance is 276.5 miles.
The best way to get from Des Moines to Madison without a car is to bus which takes 10h 45m and costs $45 - $220.
It takes approximately 4h 31m to get from Des Moines to Madison, including transfers.
Des Moines to Madison bus services, operated by Jefferson Lines, depart from Des Moines station.
The best way to get from Des Moines to Madison is to fly which takes 4h 31m and costs $180 - $1,200. Alternatively, you can bus, which costs $45 - $220 and takes 10h 45m.
Des Moines to Madison bus services, operated by Jefferson Lines, arrive at St. Paul station.
Yes, the driving distance between Des Moines to Madison is 277 miles. It takes approximately 5h 4m to drive from Des Moines to Madison.
What companies run services between Des Moines, IA, USA and Madison, WI, USA?
United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to Dane County Regional Airport-Truax Field (MSN) hourly. Alternatively, you can take a bus from Des Moines to Madison via St. Paul and Saint Paul Union Depot in around 10h 45m.
- Website
- united.com
Flights from Des Moines to Dane County Regional Airport-Truax Field via Chicago O'Hare International Airport
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $160–1,100
Flights from Des Moines to Dane County Regional Airport-Truax Field via Denver
- Ave. Duration
- 7h 45m
- When
- Every day
- Estimated price
- $330–1,600
Flights from Des Moines to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $170–1,100
Flights from Des Moines to General Mitchell International Airport via Denver
- Ave. Duration
- 7h 53m
- When
- Every day
- Estimated price
- $380–1,800
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $60–420
- Website
- delta.com
Flights from Des Moines to Dane County Regional Airport-Truax Field via Minneapolis
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $170–1,100
Flights from Des Moines to Dane County Regional Airport-Truax Field via Detroit
- Ave. Duration
- 5h 49m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $230–1,300
Flights from Des Moines to Dane County Regional Airport-Truax Field via Atlanta
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $340–1,600
Flights from Des Moines to General Mitchell International Airport via Minneapolis
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $200–1,200
Flights from Des Moines to General Mitchell International Airport via Atlanta
- Ave. Duration
- 5h 51m
- When
- Every day
- Estimated price
- $370–1,800
Flights from Des Moines to General Mitchell International Airport via Detroit
- Ave. Duration
- 6h 49m
- When
- Every day
- Estimated price
- $240–1,400
- Website
- aa.com
Flights from Des Moines to Dane County Regional Airport-Truax Field via Chicago O'Hare International Airport
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $160–1,100
Flights from Des Moines to Dane County Regional Airport-Truax Field via Dallas/Ft.Worth
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $340–1,600
Flights from Des Moines to Dane County Regional Airport-Truax Field via Charlotte
- Ave. Duration
- 6h 40m
- When
- Saturday
- Estimated price
- $350–1,700
Flights from Des Moines to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $170–1,100
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $60–420
- Website
- southwest.com
Flights from Des Moines to General Mitchell International Airport via St. Louis
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $210–1,300
Flights from Des Moines to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 6h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $170–1,100
Flights from Des Moines to General Mitchell International Airport via Denver
- Ave. Duration
- 7h 45m
- When
- Every day
- Estimated price
- $380–1,800
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $23–110
- Book at
- https://www.jeffersonlines.com
Bus from Saint Paul Union Depot to Madison
- Ave. Duration
- 5h 45m
- Frequency
- Once daily
- Estimated price
- $24–110
- Book at
- https://www.jeffersonlines.com
Bus from Des Moines to Burnsville
- Ave. Duration
- 4h 10m
- Frequency
- Twice daily
- Estimated price
- $21–100
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Saint Paul Union Depot to Madison
- Ave. Duration
- 4h 55m
- Frequency
- Twice daily
- Estimated price
- $40–70
- Schedules at
- flixbus.com
Bus from Mitchell Airport to Madison, WI-Lake St.
- Ave. Duration
- 2h 10m
- Frequency
- Twice daily
- Estimated price
- $21–30
- Schedules at
- flixbus.com
- Phone
- +1 414-266-4409
- ticketinfo@badgerbus.com
- Website
- badgerbus.com
Bus from Mitchell Airport to Madison, WI-Lake St.
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- $24–35
- Website
- https://badgerbus.com
Bus from Mall of America - IKEA - Bloomington to Madison, WI-Lake St.
- Ave. Duration
- 5h 40m
- Frequency
- Twice a week
- Estimated price
- $55–80
- Website
- https://badgerbus.com
- Phone
- +1 800-236-1240
- Website
- golamers.com
Bus from Mitchell Airport to Madison, WI-Lake St.
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $22–55
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
- Phone
- +1 608-752-5407
- vangalder@coachusa.com
- Website
- coachusa.com
Bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 2h 50m
- Frequency
- Hourly
- Estimated price
- $20–40
- Website
- https://www.coachusa.com/van-galder-bus-company
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 50m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- https://www.coachusa.com/van-galder-bus-company
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
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