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How to get fromDes Moines to Madisonby plane, bus (Greyhound, Flixbus), car, bus, bus (Greyhound) or bus (Flixbus)

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There are 6 ways to get from Des Moines to Madison by plane, bus (Greyhound, Flixbus), car, bus, bus (Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Dane County Regional Airport-Truax Field

    best
    1. Fly from Des Moines (DSM) to Dane County Regional Airport-Truax Field (MSN)plane plane DSM - MSN
    4h 36m
    $120–673
  2. Drive 274.9 mi

    cheapest
    1. Drive from Des Moines to Madisoncar car 274.9 mi
    5h 5m
    $51–73
  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago Bus Station to Madisonbus bus FlixBus 2514 / ...
    11h 25m
    $73–138
  4. Fly to General Mitchell International Airport, bus

    1. Fly from Des Moines (DSM) to General Mitchell International Airport (MKE)plane plane DSM - MKE
    2. Take the bus from Mitchell Airport to Madison, WI-Lake St.bus bus
    6h 34m
    $149–840
  5. Bus via Chicago

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus Van Galder
    11h 50m
    $75–148
  6. Bus via Saint Paul

    1. Take the bus from Des Moines to St. Paulbus bus Jefferson 802
    2. Take the bus from St. Paul to UW-Madisonbus bus Minneapolis / ...
    12h 5m
    $100–155

Des Moines to Madison by bus

Calendar19Weekly Buses
Duration11h 25mAverage Duration
Ticket$73Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Madison, WI, USA?

United Airlines, Delta, and American Airlines fly from Des Moines (DSM) to Dane County Regional Airport-Truax Field (MSN) hourly. Alternatively, you can take a bus from Des Moines to Madison via Chicago Bus Station in around 11h 25m.

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