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How to get fromDes Moines to Irontonby plane, bus, train, car, or bus (Greyhound)

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There are 6 ways to get from Des Moines to Ironton by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tri-State Airport

    best
    1. Fly from Des Moines (DSM) to Tri-State Airport (HTS)plane plane DSM - HTS
    5h 21m
    $203–766

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Columbusbus bus
    3. Take the bus from Columbus to Ashland Bus Stationbus bus
    18h 36m
    $125–256

  3. Bus, train

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train Cardinal
    17h 16m
    $171–331

  4. Drive 700.1 mi

    1. Drive from Des Moines to Irontoncar car 700.1 mi
    12h 28m
    $128–185

  5. Fly to Blue Grass Airport, drive

    1. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    2. Drive from Lexington-Airport-LEX to Irontoncar car
    6h 38m
    $251–1,256

  6. Fly to Yeager Airport, train

    1. Fly from Des Moines (DSM) to Yeager Airport (CRW)plane plane DSM - CRW
    2. Take the train from Charleston Station to Ashland Amtrak Stationtrain train
    7h 34m
    $198–802

Des Moines (DSM) to Tri-State Airport (HTS) flights

Calendar17Weekly Planes
Duration5h 46mAverage Duration
Ticket$149Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Ironton.ExpandLaunch map view
  • Distance: 649 mi
  • Duration: 5h 21m

What companies run services between Des Moines, IA, USA and Ironton, OH, USA?

American Airlines and Allegiant Air fly from Des Moines (DSM) to Tri-State Airport (HTS) twice daily. Alternatively, you can take a bus from Des Moines to Ironton via Indianapolis Union Station, Columbus, and Ashland Bus Station in around 18h 36m.

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