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How to get fromDes Moines to Irontonby plane, bus, train, car, or bus (Greyhound)

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There are 7 ways to get from Des Moines to Ironton by plane, bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tri-State Airport

    best
    1. Fly from Des Moines (DSM) to Tri-State Airport (HTS)plane plane DSM - HTS
    5h 28m
    $183–716

  2. Bus

    cheapest
    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Columbusbus bus
    3. Take the bus from Columbus to Ashland Bus Stationbus bus
    19h 26m
    $122–246

  3. Bus, train

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus Greyhound US0157S
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train Cardinal
    17h 16m
    $169–326

  4. Drive 700.1 mi

    1. Drive from Des Moines to Irontoncar car 700.1 mi
    12h 28m
    $128–185

  5. Fly to Blue Grass Airport, drive

    1. Fly from Des Moines (DSM) to Blue Grass Airport (LEX)plane plane DSM - LEX
    2. Drive from Lexington-Airport-LEX to Irontoncar car
    6h 38m
    $221–1,056

  6. Fly to Yeager Airport, train

    1. Fly from Des Moines (DSM) to Yeager Airport (CRW)plane plane DSM - CRW
    2. Take the train from Charleston Station to Ashland Amtrak Stationtrain train
    7h 34m
    $178–702

  7. Fly to John Glenn Columbus International Airport, bus

    1. Fly from Des Moines (DSM) to John Glenn Columbus International Airport (CMH)plane plane DSM - CMH
    2. Take the bus from Columbus to Ashland Bus Stationbus bus
    8h 29m
    $175–870

Des Moines (DSM) to Tri-State Airport (HTS) flights

Calendar13Weekly Planes
Duration6h 24mAverage Duration
Ticket$131Cheapest Price
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Questions & Answers

Map of how to get from Des Moines to Ironton.ExpandLaunch map view
  • Distance: 649 mi
  • Duration: 5h 28m

What companies run services between Des Moines, IA, USA and Ironton, OH, USA?

American Airlines and Allegiant Air fly from Des Moines (DSM) to Tri-State Airport (HTS) twice daily. Alternatively, you can take a bus from Des Moines to Ironton via Indianapolis Union Station, Columbus, and Ashland Bus Station in around 19h 26m.

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Train operators
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