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How to get fromDes Moines to Independenceby bus (Greyhound), car, plane, or bus

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There are 4 ways to get from Des Moines to Independence by bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Des Moines to Kansas City Bus Stationbus bus Greyhound US0156
    4h 58m
    $29–55
  2. Drive 189.5 mi

    1. Drive from Des Moines to Independencecar car 189.5 mi
    3h 18m
    $35–50
  3. Fly

    1. Fly from Des Moines (DSM) to Kansas City (MCI)plane plane DSM - MCI
    7h 16m
    $178–921
  4. Bus via Des Moines

    1. Take the bus from Des Moines to Kansas Citybus bus Jefferson Lines 803 / ...
    5h 12m
    $53–72

Des Moines to Independence by bus and foot (Greyhound)

Calendar12Weekly Services
Duration4h 58mAverage Duration
Ticket$29Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Independence, MO, USA?

Greyhound USA operates a bus from Des Moines to Kansas City Bus Station twice daily. Tickets cost $29–60 and the journey takes 3h 15m. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Kansas City (MCI) hourly.

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