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How to get fromDes Moines to Frederickby plane, bus, bus (Greyhound), train or car

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There are 7 ways to get from Des Moines to Frederick by plane, bus, bus (Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ronald Reagan Washington National Airport, bus

    best
    1. Fly from Des Moines (DSM) to Ronald Reagan Washington National Airport (DCA)plane plane DSM - DCA
    2. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus
    5h 23m
    $304–1,534

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the bus from Chicago Bus Station to Frederick Bus Stationbus bus Greyhound US0164
    23h 20m
    $141–237

  3. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Rockville Amtraktrain train
    3. Take the train from ROCKVILLE MARC wb to FREDERICK MARC wbtrain train
    27h 2m
    $173–377

  4. Drive 961.7 mi

    1. Drive from Des Moines to Frederickcar car 961.7 mi
    16h 19m
    $176–254

  5. Fly to Baltimore-Washington International Airport, bus

    1. Fly from Des Moines (DSM) to Baltimore-Washington International Airport (BWI)plane plane DSM - BWI
    2. Take the bus from Baltimore Airport to Frederick Bus Stationbus bus
    6h 53m
    $228–861

  6. Fly to Washington Dulles International Airport, bus

    1. Fly from Des Moines (DSM) to Washington Dulles International Airport (IAD)plane plane DSM - IAD
    2. Take the bus from Market St & Harrison St to Frederick Transit Stationbus bus
    7h 42m
    $182–847

  7. Fly to Philadelphia International Airport, train, bus

    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane plane DSM - PHL
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Take the bus from BWI Amtrak Station to Frederick Transit Centerbus bus
    7h 8m
    $254–1,611

Des Moines to Frederick by bus (Greyhound)

Calendar14Weekly Buses
Duration23h 20mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Frederick, MD, USA?

You can take a bus from Des Moines to Frederick Bus Station via Chicago Bus Station in around 23h 20m.

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