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How to get fromDes Moines to Frederickby plane, bus, bus (Greyhound), train or car

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There are 10 ways to get from Des Moines to Frederick by plane, bus, bus (Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ronald Reagan Washington National Airport, bus

    best
    1. Fly from Des Moines (DSM) to Ronald Reagan Washington National Airport (DCA)planeDSM - DCA
    2. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus
    5h 16m
    $294–1,434

  2. Bus via Des Moines

    cheapest
    1. Take the bus from Des Moines to ChicagobusDes Moines
    2. Take the bus from Chicago Bus Station to Frederick Bus StationbusGreyhound US0164
    23h 30m
    $146–294

  3. Bus

    1. Take the bus from Des Moines to ChicagobusOmaha
    2. Take the bus from Chicago Bus Station to Frederick Bus StationbusGreyhound US0164
    22h 25m
    $158–283

  4. Bus, train

    1. Take the bus from Des Moines to Chicagobus
    2. Take the train from Chicago Union Station to Rockville Amtraktrain
    3. Take the train from ROCKVILLE MARC wb to FREDERICK MARC wbtrain
    26h 7m
    $180–423

  5. Drive 961.7 mi

    1. Drive from Des Moines to Frederickcar961.7 mi
    16h 8m
    $176–254

  6. Fly to Baltimore-Washington International Airport, bus

    1. Fly from Des Moines (DSM) to Baltimore-Washington International Airport (BWI)planeDSM - BWI
    2. Take the bus from Baltimore Airport to Frederick Bus Stationbus
    6h 22m
    $228–861

  7. Fly to Washington Dulles International Airport, bus

    1. Fly from Des Moines (DSM) to Washington Dulles International Airport (IAD)planeDSM - IAD
    2. Take the bus from Market St & Harrison St to Frederick Transit Stationbus
    7h 44m
    $172–847

  8. Fly to Philadelphia International Airport, train, bus

    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)planeDSM - PHL
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain
    3. Take the bus from BWI Amtrak Station to Frederick Transit Centerbus
    7h 8m
    $254–1,561

  9. Bus, train via Des Moines

    1. Take the bus from Des Moines to Chicagobus
    2. Take the train from Chicago Union Station to Rockville Amtraktrain
    3. Take the train from ROCKVILLE MARC wb to FREDERICK MARC wbtrain
    27h 12m
    $168–434

  10. Bus, train via Galesburg

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to Galesburgbus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
    4. Take the train from Chicago Union Station to Rockville Amtraktrain
    5. Take the train from ROCKVILLE MARC wb to FREDERICK MARC wbtrain
    28h 43m
    $202–487

Des Moines to Frederick by bus

Calendar7Weekly Buses
Duration22h 25mAverage Duration
Ticket$158Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Frederick, MD, USA?

You can take a bus from Des Moines to Frederick Bus Station via Chicago Bus Station in around 22h 25m.

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