There are 10 ways to get from Des Moines to Florida by plane, bus (Greyhound, Flixbus), bus, train, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Tallahassee
best- Fly from Des Moines (DSM) to Tallahassee (TLH)plane DSM - TLH
5h 42m$260–1,248Fly to Fort Lauderdale–Hollywood International Airport
cheapest- Fly from Des Moines (DSM) to Fort Lauderdale–Hollywood International Airport (FLL)plane DSM - FLL
4h 17m$150–674Bus
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Jacksonvillebus
30h 24m$160–420Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
- Take the train from Chicago Union Station to Jacksonvilletrain Floridian
43h 49m$245–700Drive 1,188.7 mi
- Drive from Des Moines to Jacksonvillecar 1,188.7 mi
21h 47m$217–314Fly to Miami International Airport
- Fly from Des Moines (DSM) to Miami International Airport (MIA)plane DSM - MIA
4h 15m$188–871Fly to Punta Gorda Airport, taxi
- Fly from Des Moines (DSM) to Punta Gorda Airport (PGD)plane DSM - PGD
- Take the taxi from Punta Gorda Airport (PGD) to Cape Coraltaxi
3h 59m$238–946Fly to Orlando Sanford
- Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane DSM - SFB
3h 38m$233–891Fly to Saint Petersburg–Clearwater International Airport
- Fly from Des Moines (DSM) to Saint Petersburg–Clearwater International Airport (PIE)plane DSM - PIE
4h 58m$181–824Bus, train via Saint Paul
- Take the bus from Des Moines to St. Paulbus
- Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Jacksonvilletrain
2d 1h$285–917
Des Moines to Florida by bus
Questions & Answers
The cheapest way to get from Des Moines to Florida is to drive which costs $210 - $320 and takes 21h 47m.
The fastest way to get from Des Moines to Florida is to fly which takes 3h 38m and costs $230 - $900.
No, there is no direct bus from Des Moines to Florida. However, there are services departing from Des Moines and arriving at Newnan St + Ashley St via Chicago Bus Station, Atlanta Bus Station and JRTC Bay J. The journey, including transfers, takes approximately 30h 24m.
The distance between Des Moines and Florida is 946 miles. The road distance is 1195.6 miles.
The best way to get from Des Moines to Florida without a car is to bus which takes 30h 24m and costs $160 - $420.
It takes approximately 5h 42m to get from Des Moines to Florida, including transfers.
Des Moines to Florida bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Florida is to fly which takes 5h 42m and costs $260 - $1,300. Alternatively, you can bus, which costs $160 - $420 and takes 30h 24m.
Des Moines to Florida bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Florida is 1h ahead of Des Moines. It is currently 3:25 AM in Des Moines and 4:25 AM in Florida.
What companies run services between Des Moines, IA, USA and Florida, USA?
American Airlines and Delta fly from Des Moines (DSM) to Tallahassee (TLH) every 4 hours. Alternatively, you can take a bus from Des Moines to Newnan St + Ashley St via Chicago Bus Station, Atlanta Bus Station, Jacksonville, and JRTC Bay J in around 30h 24m.
- Website
- aa.com
Flights from Des Moines to Tallahassee via Dallas/Ft.Worth
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $290–1,400
Flights from Des Moines to Tallahassee via Charlotte
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $260–1,300
Flights from Des Moines to Tallahassee via Reagan Washington
- Ave. Duration
- 8h 10m
- When
- Every day
- Estimated price
- $320–1,500
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Miami International Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $170–850
- Website
- delta.com
Flights from Des Moines to Tallahassee via Atlanta
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $130–650
Flights from Des Moines to Miami International Airport via Atlanta
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $170–850
- Website
- allegiantair.com
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 18m
- When
- Thursday and Sunday
- Estimated price
- $130–650
Flights from Des Moines to Punta Gorda Airport
- Ave. Duration
- 3h 5m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–850
Flights from Des Moines to Orlando Sanford
- Ave. Duration
- 2h 51m
- When
- Monday, Friday, and Saturday
- Estimated price
- $160–800
Flights from Des Moines to Saint Petersburg–Clearwater International Airport
- Ave. Duration
- 2h 49m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $160–800
- Website
- southwest.com
Flights from Des Moines to Fort Lauderdale–Hollywood International Airport via St. Louis
- Ave. Duration
- 5h 10m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $130–650
Flights from Des Moines to Miami International Airport via St. Louis
- Ave. Duration
- 5h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $170–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Jacksonville
- Ave. Duration
- 34h 45m
- Frequency
- Once daily
- Estimated price
- $200–600
- Website
- https://www.amtrak.com/home.html
Train from St. Paul-Minneapolis to Chicago Union Station
- Ave. Duration
- 7h 24m
- Frequency
- 3 times a day
- Estimated price
- $60–210
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $40–100
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 15m
- Frequency
- 4 times a day
- Estimated price
- $70–190
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Jacksonville
- Ave. Duration
- 9h 15m
- Frequency
- Once daily
- Estimated price
- $45–110
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 14h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–180
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Jacksonville
- Ave. Duration
- 6h 35m
- Frequency
- 3 times a day
- Estimated price
- $50–130
- Schedules at
- flixbus.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $23–110
- Book at
- https://www.jeffersonlines.com
- Ave. Duration
- 41 min
- Estimated price
- $60–75
Gulf Coast Car Service
- Phone
- +1 941-391-8800
- Website
- gulfcoastcarservice.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Yes, the driving distance between Des Moines to Florida is 1196 miles. It takes approximately 21h 47m to drive from Des Moines to Florida.
There are 326+ hotels available in Florida.










