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How to get fromDes Moines to Floridaby plane, bus (Greyhound, Flixbus), bus, train, car or taxi

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There are 10 ways to get from Des Moines to Florida by plane, bus (Greyhound, Flixbus), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tallahassee

    best
    1. Fly from Des Moines (DSM) to Tallahassee (TLH)plane plane DSM - TLH
    5h 42m
    $260–1,248
  2. Fly to Fort Lauderdale–Hollywood International Airport

    cheapest
    1. Fly from Des Moines (DSM) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane DSM - FLL
    4h 17m
    $150–674
  3. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    30h 24m
    $160–420
  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123 / ...
    2. Take the train from Chicago Union Station to Jacksonvilletrain train Floridian
    43h 49m
    $245–700
  5. Drive 1,188.7 mi

    1. Drive from Des Moines to Jacksonvillecar car 1,188.7 mi
    21h 47m
    $217–314
  6. Fly to Miami International Airport

    1. Fly from Des Moines (DSM) to Miami International Airport (MIA)plane plane DSM - MIA
    4h 15m
    $188–871
  7. Fly to Punta Gorda Airport, taxi

    1. Fly from Des Moines (DSM) to Punta Gorda Airport (PGD)plane plane DSM - PGD
    2. Take the taxi from Punta Gorda Airport (PGD) to Cape Coraltaxi taxi
    3h 59m
    $238–946
  8. Fly to Orlando Sanford

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    3h 38m
    $233–891
  9. Fly to Saint Petersburg–Clearwater International Airport

    1. Fly from Des Moines (DSM) to Saint Petersburg–Clearwater International Airport (PIE)plane plane DSM - PIE
    4h 58m
    $181–824
  10. Bus, train via Saint Paul

    1. Take the bus from Des Moines to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Jacksonvilletrain train
    2d 1h
    $285–917

Des Moines to Florida by bus

Calendar19Weekly Buses
Duration30h 24mAverage Duration
Ticket$160Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Florida, USA?

American Airlines and Delta fly from Des Moines (DSM) to Tallahassee (TLH) every 4 hours. Alternatively, you can take a bus from Des Moines to Newnan St + Ashley St via Chicago Bus Station, Atlanta Bus Station, Jacksonville, and JRTC Bay J in around 30h 24m.

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