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How to get fromDes Moines to Floridaby plane, bus (Greyhound, Flixbus), bus, train, car, or taxi

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There are 8 ways to get from Des Moines to Florida by plane, bus (Greyhound, Flixbus), bus, train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Tallahassee

    best
    1. Fly from Des Moines (DSM) to Tallahassee (TLH)plane plane DSM - TLH
    4h 56m
    $191–850

  2. Fly to Jacksonville

    cheapest
    1. Fly from Des Moines (DSM) to Jacksonville (JAX)plane plane DSM - JAX
    6h 2m
    $160–726

  3. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Jacksonvillebus bus
    30h
    $208–351

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Jacksonvilletrain train Floridian
    43h 55m
    $453–985

  5. Drive  1,177.5 mi

    1. Drive from Des Moines to Jacksonvillecar car 1,177.5 mi
    22h 13m
    $215–311

  6. Fly to Fort Lauderdale–Hollywood International Airport

    1. Fly from Des Moines (DSM) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane DSM - FLL
    3h 55m
    $181–826

  7. Fly to Orlando Sanford

    1. Fly from Des Moines (DSM) to Orlando Sanford (SFB)plane plane DSM - SFB
    3h 27m
    $209–748

  8. Fly to Punta Gorda Airport, taxi

    1. Fly from Des Moines (DSM) to Punta Gorda Airport (PGD)plane plane DSM - PGD
    2. Take the taxi from Punta Gorda Airport (PGD) to Cape Coraltaxi taxi
    3h 50m
    $229–823

Des Moines to Florida by bus

Calendar7Weekly Buses
Duration30hAverage Duration
Ticket$208Cheapest Price
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Comparing Your Travel Options

Map of how to get from Des Moines to Florida.ExpandLaunch map view
  • Distance: 940.5 mi
  • Duration: 4h 56m

What companies run services between Des Moines, IA, USA and Florida, USA?

Delta and American Airlines fly from Des Moines (DSM) to Tallahassee (TLH) every 3 hours. Alternatively, you can take a bus from Des Moines to Newnan St + Ashley St via Indianapolis Union Station, Atlanta Bus Station, Jacksonville, and JRTC Bay J in around 30h.

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