Travel from Des-Moines to East-St-Louis

Bus or fly from Des Moines to East St. Louis?

Southwest Airlines flies from Des Moines to East St. Louis twice daily. Alternatively, Jefferson Lines operates a bus from Des Moines to East St. Louis hourly. Tickets cost $40 - $55 and the journey takes 3 h 10 min. 2 other operators also service this route.

Travel Guides

Need to know: GreyhoundRome2rio’s guide on the bus operator has all the information you need
Want to know more about US trains?Rome2rio has everything you need to know about travelling with Amtrak

How to get from Des Moines to East St. Louis

From Platform L line 8 bus to Des Moines airport, fly to St. Louis airport, then train to East St. Louis. 3 h 3 min $553. From Des Moines, IA bus to Kansas City, MO, bus to CIVIC CENTER station, then train to 5TH & MISSOURI station. 9 h 5 min $78. From Des Moines, IA bus to On Troost Between 11Th & 12Th Northbound Midblock, line 71 bus to Metro Center On Main At 12Th St Sb, tram to Kansas City Amtrak, train to CIVIC CENTER station, then train to 5TH & MISSOURI station. 10 h 28 min $141. From Des Moines, IA bus to Burlington, IA, bus to CIVIC CENTER station, then train to 5TH & MISSOURI station. 17 h $146. From Des Moines drive to East St. Louis. 6 h 29 min $42.

Operators from Des Moines to East St. Louis

Close Print Itinerary
  1. Here are 5 options to get from
    Des Moines to East St. Louis:

    1. Trip:
      1 Fly
      • One-Way approx: USD $194 - $904
      • Duration: 3 h 3 min
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      • Trip:
        1 Fly
        • One-Way approx: USD $194 - $904
        • Duration: 3 h 3 min
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    2. Trip:
      2 Bus Greyhound USA
      • One-Way approx: USD $72 - $127
      • Duration: 9 h 5 min
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      • Trip:
        2 Bus Greyhound USA
        • One-Way approx: USD $72 - $127
        • Duration: 9 h 5 min
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    3. Trip:
      3 Bus, train
      • One-Way approx: USD $95 - $189
      • Duration: 10 h 28 min
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      • Trip:
        3 Bus, train
        • One-Way approx: USD $95 - $189
        • Duration: 10 h 28 min
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    4. Trip:
      4 Bus Burlington Trailways
      • One-Way approx: USD $84 - $154
      • Duration: 17 h
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      • Trip:
        4 Bus Burlington Trailways
        • One-Way approx: USD $84 - $154
        • Duration: 17 h
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    5. Trip:
      5 Drive
      • One-Way approx: USD $30 - $50
      • Duration: 6 h 29 min
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      • Trip:
        5 Drive
        • One-Way approx: USD $30 - $50
        • Duration: 6 h 29 min
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