There are 6 ways to get from Des Moines to Chicago Loop by plane, bus, car, subway, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago O'Hare International Airport
best- Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane DSM - ORD
2h 30m$85–446Bus via Des Moines #2
cheapest- Take the bus from Des Moines to Chicagobus Des Moines
7h 29m$59–157Bus
- Take the bus from Des Moines to Chicagobus Omaha
6h 10m$65–143Drive 330.9 mi
- Drive from Des Moines to Chicago Loopcar 330.9 mi
5h 31m$61–88Fly to Chicago Midway International Airport, subway
- Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane DSM - MDW
- Take the subway from Midway to Washington/Wellssubway
2h 18m$110–626Bus via Des Moines (Greyhound)
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
7h 19m$60–103
Des Moines to Chicago Loop by bus
Questions & Answers
The cheapest way to get from Des Moines to Chicago Loop is to drive which costs $60 - $90 and takes 5h 31m.
The fastest way to get from Des Moines to Chicago Loop is to fly and subway which takes 2h 18m and costs $110 - $650.
Yes, there is a direct bus departing from Des Moines and arriving at Chicago. Services depart once daily, and operate every day. The journey takes approximately 6h 10m.
The distance between Des Moines and Chicago Loop is 324 miles. The road distance is 332.9 miles.
The best way to get from Des Moines to Chicago Loop without a car is to bus which takes 6h 10m and costs $65 - $150.
It takes approximately 2h 30m to get from Des Moines to Chicago Loop, including transfers.
Des Moines to Chicago Loop bus services, operated by Burlington Trailways, depart from Des Moines station.
The best way to get from Des Moines to Chicago Loop is to fly which takes 2h 30m and costs $85 - $450. Alternatively, you can bus, which costs $65 - $150 and takes 6h 10m.
Des Moines to Chicago Loop bus services, operated by Burlington Trailways, arrive at Chicago station.
Yes, the driving distance between Des Moines to Chicago Loop is 333 miles. It takes approximately 5h 31m to drive from Des Moines to Chicago Loop.
What companies run services between Des Moines, IA, USA and Chicago Loop, IL, USA?
American Airlines and United Airlines fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, Burlington Trailways operates a bus from Des Moines to Chicago once daily. Tickets cost $65–143 and the journey takes 6h 10m.
- Website
- aa.com
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $65–420
- Website
- united.com
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $65–420
- Website
- southwest.com
Flights from Des Moines to Chicago Midway International Airport
- Ave. Duration
- 1h 20m
- When
- Monday, Thursday, and Friday
- Estimated price
- $90–600
Flights from Des Moines to Chicago Midway International Airport via St. Louis
- Ave. Duration
- 3h 21m
- When
- Every day
- Estimated price
- $110–650
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Midway to Washington/Wells
- Ave. Duration
- 29 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from Des Moines to Chicago
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $65–143
- Website
- https://burlingtontrailways.com
- Saver Fares
- $65–100
- Flexible Fares
- $90–140
- Saver Fare
- $104
- Flex Fare
- $143
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $55–100
- Website
- https://www.greyhound.com/
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