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How to get fromDes Moines to Chamberlainby bus, car or plane

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There are 6 ways to get from Des Moines to Chamberlain by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive

    best
    1. Take the bus from Des Moines to Omaha, NEbus bus
    2. Take the bus from Omaha to Sioux Fallsbus bus
    3. Take the bus from Sioux Falls to Vivianbus bus
    4. Drive from Vivian to Chamberlaincar car
    11h 56m
    $68–226

  2. Drive 419.3 mi

    1. Drive from Des Moines to Chamberlaincar car 419.3 mi
    6h 24m
    $77–111

  3. Fly to Pierre Municipal Airport, drive

    1. Fly from Des Moines (DSM) to Pierre Municipal Airport (PIR)plane plane DSM - PIR
    2. Drive from Pierre Municipal Airport (PIR) to Chamberlaincar car
    7h 57m
    $184–845

  4. Fly to Rapid City, drive

    1. Fly from Des Moines (DSM) to Rapid City (RAP)plane plane DSM - RAP
    2. Drive from Rapid-City-Airport-RAP to Chamberlaincar car
    7h 36m
    $173–826

  5. Fly to Aberdeen Regional Airport, drive

    1. Fly from Des Moines (DSM) to Aberdeen Regional Airport (ABR)plane plane DSM - ABR
    2. Drive from Aberdeen Regional Airport (ABR) to Chamberlaincar car
    7h 42m
    $147–716

  6. Fly to Sioux Falls, bus, drive

    1. Fly from Des Moines (DSM) to Sioux Falls (FSD)plane plane DSM - FSD
    2. Take the bus from Sioux Falls to Vivianbus bus
    3. Drive from Vivian to Chamberlaincar car
    8h 32m
    $149–783

Des Moines (DSM) to Pierre Municipal Airport (PIR) flights

Calendar24Weekly Planes
Duration7h 23mAverage Duration
Ticket$154Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Chamberlain, SD, USA?

There is no direct connection from Des Moines to Chamberlain. However, you can take the bus to Omaha, NE, take the bus to Sioux Falls, take the bus to Vivian, then drive to Chamberlain. Alternatively, you can drive from Des Moines to Chamberlain in around 6h 24m.

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