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How to get fromDes Moines to Bostonby plane, bus, train, bus (Greyhound, Flixbus) or car

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There are 5 ways to get from Des Moines to Boston by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Des Moines (DSM) to Boston Logan Airport (BOS)plane plane DSM - BOS
    3h 1m
    $158–721

  2. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Bostontrain train Lake Shore Limited
    30h 16m
    $324–704

  3. Bus

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis to New York Midtownbus bus
    3. Take the bus from New York Midtown to Bostonbus bus
    32h 14m
    $202–373

  4. Drive 1,296.5 mi

    1. Drive from Des Moines to Bostoncar car 1,296.5 mi
    22h 5m
    $237–342

  5. Bus, train via Bloomington

    1. Take the bus from Des Moines to Bloomington-Normalbus bus
    2. Take the train from Bloomington-Normal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bostontrain train
    32h 36m
    $347–765

Des Moines to Boston by bus, foot, and train

Calendar7Weekly Services
Duration30h 16mAverage Duration
Ticket$324Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Boston, MA, USA?

Allegiant Air, Southwest Airlines, and three other airlines fly from Des Moines (DSM) to Boston Logan Airport (BOS) every 2 hours. Alternatively, you can take a bus from Des Moines to Boston via Indianapolis, Illinois St (Greyhound Bus Station), Indianapolis, and New York Midtown in around 32h 14m.

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