Rome2Rio

How to get fromDes Moines to Baltimoreby plane, train, bus (Greyhound), bus, car, subway or bus (Greyhound, Flixbus)

Find Transport to Baltimore

See all options

There are 10 ways to get from Des Moines to Baltimore by plane, train, bus (Greyhound), bus, car, subway, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ronald Reagan Washington National Airport, train

    best
    1. Fly from Des Moines (DSM) to Ronald Reagan Washington National Airport (DCA)plane plane DSM - DCA
    2. Take the train from Washington Union Station to Baltimore Penn Stationtrain train
    3h 55m
    $224–1,728

  2. Fly to Washington Dulles International Airport, subway, train

    cheapest
    1. Fly from Des Moines (DSM) to Washington Dulles International Airport (IAD)plane plane DSM - IAD
    2. Take the subway from Washington Dulles International Airport, Silver Line Center Platform to New Carrollton, Orange Line Center Platformsubway subway
    3. Take the train from New Carrollton Amtrak Station to Baltimore Penn Stationtrain train
    7h 16m
    $132–832

  3. Bus (Greyhound)

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0164
    25h 50m
    $174–342

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Rockville Amtraktrain train
    3. Take the train from Washington Union Station to Baltimore Penn Stationtrain train
    26h 15m
    $258–1,158

  5. Drive 1,008 mi

    1. Drive from Des Moines to Baltimorecar car 1,008 mi
    17h 6m
    $184–266

  6. Fly to Baltimore-Washington International Airport

    1. Fly from Des Moines (DSM) to Baltimore-Washington International Airport (BWI)plane plane DSM - BWI
    5h 21m
    $140–673

  7. Fly to Philadelphia International Airport, train

    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)plane plane DSM - PHL
    2. Take the train from 30th Street Station to Baltimore Penn Stationtrain train
    4h 41m
    $176–779

  8. Bus via Harrisburg

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus bus
    3. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus bus
    26h 45m
    $166–296

  9. Bus, train via Bloomington

    1. Take the bus from Des Moines to Bloomington-Normalbus bus
    2. Take the train from Bloomington-Normal to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Rockville Amtraktrain train
    4. Take the train from Washington Union Station to Baltimore Penn Stationtrain train
    28h 35m
    $281–1,220

  10. Bus, train #2

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Baltimore Penn Stationtrain train Cardinal
    33h
    $304–702

Des Moines to Baltimore by bus (Greyhound)

Calendar14Weekly Buses
Duration25h 50mAverage Duration
Ticket$174Cheapest Price
See schedules

Questions & Answers

What companies run services between Des Moines, IA, USA and Baltimore, MD, USA?

You can take a bus from Des Moines to Baltimore Downtown Bus Station via Chicago Bus Station in around 25h 50m. Alternatively, Delta, United Airlines, and two other airlines fly from Des Moines (DSM) to Baltimore-Washington International Airport (BWI) hourly.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Where to next?

Trips from Des Moines

Trips to Baltimore

Popular routes