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How to get fromDes Moines to Baltimoreby plane, train, bus (Greyhound), bus, car, subway or bus (Flixbus, Greyhound)

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There are 10 ways to get from Des Moines to Baltimore by plane, train, bus (Greyhound), bus, car, subway, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Ronald Reagan Washington National Airport, train

    best
    1. Fly from Des Moines (DSM) to Ronald Reagan Washington National Airport (DCA)planeDSM - DCA
    2. Take the train from Washington Union Station to Baltimore Penn Stationtrain
    3h 46m
    $294–2,028

  2. Bus

    cheapest
    1. Take the bus from Des Moines to ChicagobusOmaha
    2. Take the bus from Chicago Bus Station to Baltimore Downtown Bus StationbusGreyhound US0164
    24h 50m
    $148–363

  3. Bus, train

    1. Take the bus from Des Moines to Chicagobus
    2. Take the train from Chicago Union Station to Rockville Amtraktrain
    3. Take the train from Washington Union Station to Baltimore Penn Stationtrain
    25h 20m
    $202–1,019

  4. Drive 1,008 mi

    1. Drive from Des Moines to Baltimorecar1,008 mi
    16h 56m
    $184–266

  5. Fly to Baltimore-Washington International Airport

    1. Fly from Des Moines (DSM) to Baltimore-Washington International Airport (BWI)planeDSM - BWI
    4h 50m
    $160–723

  6. Fly to Philadelphia International Airport, train

    1. Fly from Des Moines (DSM) to Philadelphia International Airport (PHL)planeDSM - PHL
    2. Take the train from 30th Street Station to Baltimore Penn Stationtrain
    4h 41m
    $181–1,421

  7. Fly to Washington Dulles International Airport, subway, train

    1. Fly from Des Moines (DSM) to Washington Dulles International Airport (IAD)planeDSM - IAD
    2. Take the subway from Washington Dulles International Airport, Silver Line Center Platform to New Carrollton, Orange Line Center Platformsubway
    3. Take the train from New Carrollton Amtrak Station to Baltimore Penn Stationtrain
    6h 58m
    $172–1,032

  8. Bus via Harrisburg

    1. Take the bus from Des Moines to Chicagobus
    2. Take the bus from Chicago Bus Station to Harrisburg Bus Stationbus
    3. Take the bus from Harrisburg Bus Station to Baltimore Downtown Bus Stationbus
    26h 55m
    $163–394

  9. Bus, train via Galesburg

    1. Take the bus from Des Moines to Burlingtonbus
    2. Take the bus from Burlington to Galesburgbus
    3. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
    4. Take the train from Chicago Union Station to Rockville Amtraktrain
    5. Take the train from Washington Union Station to Baltimore Penn Stationtrain
    27h 56m
    $224–1,088

  10. Bus, train #2

    1. Take the bus from Des Moines to ChicagobusDes Moines
    2. Take the train from Chicago Union Station to Baltimore Penn StationtrainCardinal
    33h 10m
    $176–534

Des Moines to Baltimore by bus

Calendar7Weekly Buses
Duration24h 50mAverage Duration
Ticket$148Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Baltimore, MD, USA?

You can take a bus from Des Moines to Baltimore Downtown Bus Station via Chicago Bus Station in around 24h 50m. Alternatively, Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Baltimore-Washington International Airport (BWI) every 2 hours.

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