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How to get fromDes Moines to Appletonby plane, bus (Amtrak), car, bus (Greyhound, Flixbus), bus or train

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There are 7 ways to get from Des Moines to Appleton by plane, bus (Amtrak), car, bus (Greyhound, Flixbus), bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Appleton International Airport

    best
    1. Fly from Des Moines (DSM) to Appleton International Airport (ATW)plane plane DSM - ATW
    3h 58m
    $122–594
  2. Drive 380.2 mi

    cheapest
    1. Drive from Des Moines to Appletoncar car 380.2 mi
    7h 4m
    $70–101
  3. Bus via Saint Paul

    1. Take the bus from Des Moines to St. Paulbus bus
    2. Take the bus from St. Paul-Minneapolis to Wausau Amtrak Bus Stopbus bus
    3. Take the bus from Wausau Transit Center to Appletonbus bus
    13h 30m
    $102–230
  4. Fly to Green Bay

    1. Fly from Des Moines (DSM) to Green Bay (GRB)plane plane DSM - GRB
    5h 22m
    $138–614
  5. Bus

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0155S
    2. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus FlixBus 2550
    13h 35m
    $81–146
  6. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee to Appleton Amtrak Stationbus bus
    14h 7m
    $91–211
  7. Bus, train via Saint Paul

    1. Take the bus from Des Moines to St. Paulbus bus
    2. Take the train from St. Paul-Minneapolis to Milwaukeetrain train
    3. Take the bus from Milwaukee to Appleton Amtrak Stationbus bus
    15h 4m
    $116–349

Des Moines to Appleton by bus

Calendar7Weekly Buses
Duration13h 30mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

What companies run services between Des Moines, IA, USA and Appleton, WI, USA?

American Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to Appleton International Airport (ATW) every 2 hours. Alternatively, you can take a bus from Des Moines to Appleton via St. Paul, St. Paul-Minneapolis, Wausau Amtrak Bus Stop, and Wausau Transit Center in around 13h 30m.

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