There are 5 ways to get from Des Moines to Appleton by plane, bus (Greyhound, Flixbus), car, taxi, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Appleton International Airport
best- Fly from Des Moines (DSM) to Appleton International Airport (ATW)plane DSM - ATW
4h 16m$88–391Drive 380.3 mi
cheapest- Drive from Des Moines to Appletoncar 380.3 mi
7h 7m$65–94Bus
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to Oshkoshbus
13h 45m$144–203Fly to Green Bay, taxi
- Fly from Des Moines (DSM) to Green Bay (GRB)plane DSM - GRB
- Take the taxi from Green Bay (GRB) to Appletontaxi
4h 41m$174–493Bus, train
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to Oshkoshbus
13h 59m$233–354
Des Moines (DSM) to Appleton International Airport (ATW) flights
Comparing Your Travel Options
The cheapest way to get from Des Moines to Appleton is to drive which costs $65 - $95 and takes 7h 7m.
The fastest way to get from Des Moines to Appleton is to fly which takes 4h 16m and costs $85 - $400.
No, there is no direct bus from Des Moines to Appleton. However, there are services departing from Des Moines and arriving at Oshkosh via Chicago Bus Station and Milwaukee. The journey, including transfers, takes approximately 13h 45m.
The distance between Des Moines and Appleton is 335 miles. The road distance is 382.5 miles.
The best way to get from Des Moines to Appleton without a car is to bus which takes 13h 45m and costs $140 - $210.
It takes approximately 4h 16m to get from Des Moines to Appleton, including transfers.
Des Moines to Appleton bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Appleton is to fly which takes 4h 16m and costs $85 - $400. Alternatively, you can bus, which costs $140 - $210 and takes 13h 45m.
Des Moines to Appleton bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Des Moines to Appleton is 383 miles. It takes approximately 7h 7m to drive from Des Moines to Appleton.
What companies run services between Des Moines, IA, USA and Appleton, WI, USA?
United Airlines, Delta, and two other airlines fly from Des Moines (DSM) to Appleton International Airport (ATW) every 2 hours. Alternatively, you can take a bus from Des Moines to Appleton via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Oshkosh in around 13h 45m.
- Website
- delta.com
Flights from Des Moines to Appleton International Airport via Detroit
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $80–420
Flights from Des Moines to Appleton International Airport via Minneapolis
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $55–350
Flights from Des Moines to Appleton International Airport via Atlanta
- Ave. Duration
- 7h 17m
- When
- Every day
- Estimated price
- $120–550
Flights from Des Moines to Green Bay via Detroit
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $80–420
Flights from Des Moines to Green Bay via Minneapolis
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $60–360
Flights from Des Moines to Green Bay via Atlanta
- Ave. Duration
- 7h 26m
- When
- Every day
- Estimated price
- $120–550
- Website
- united.com
Flights from Des Moines to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $55–350
Flights from Des Moines to Appleton International Airport via Denver
- Ave. Duration
- 7h 21m
- When
- Every day
- Estimated price
- $110–550
Flights from Des Moines to Green Bay via Chicago O'Hare
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $60–350
- Website
- aa.com
Flights from Des Moines to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $55–350
Flights from Des Moines to Appleton International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $120–550
Flights from Des Moines to Green Bay via Chicago O'Hare
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $60–350
- Website
- allegiantair.com
Flights from Des Moines to Appleton International Airport via Nashville
- Ave. Duration
- 5h 3m
- When
- Friday
- Estimated price
- $95–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- Every 4 hours
- Estimated price
- $16–25
- Website
- Greyhound
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
- Phone
- 920 496 3600
- Website
- example.com
Bus from Milwaukee to Oshkosh
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $20–23
- Schedules at
- golamers.com
Bus from Milwaukee to Oshkosh
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $20–23
- Schedules at
- golamers.com
- Ave. Duration
- 41 min
- Estimated price
- $95–120
Yellow Cab Green Bay
- Phone
- +1-920-435-1111
- Website
- yellowcabgreenbay.com
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Booking & Getting There
There are 65+ hotels available in Appleton.










