There are 7 ways to get from Des Moines to Appleton by plane, bus (Amtrak), car, bus (Greyhound, Flixbus), bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Appleton International Airport
best- Fly from Des Moines (DSM) to Appleton International Airport (ATW)plane DSM - ATW
3h 58m$122–594Drive 380.2 mi
cheapest- Drive from Des Moines to Appletoncar 380.2 mi
7h 4m$70–101Bus via Saint Paul
- Take the bus from Des Moines to St. Paulbus
- Take the bus from St. Paul-Minneapolis to Wausau Amtrak Bus Stopbus
- Take the bus from Wausau Transit Center to Appletonbus
13h 30m$102–230Fly to Green Bay
- Fly from Des Moines (DSM) to Green Bay (GRB)plane DSM - GRB
5h 22m$138–614Bus
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0155S
- Take the bus from Chicago Bus Station to Appleton Transit Centerbus FlixBus 2550
13h 35m$81–146Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to Appleton Amtrak Stationbus
14h 7m$91–211Bus, train via Saint Paul
- Take the bus from Des Moines to St. Paulbus
- Take the train from St. Paul-Minneapolis to Milwaukeetrain
- Take the bus from Milwaukee to Appleton Amtrak Stationbus
15h 4m$116–349
Des Moines to Appleton by bus
Questions & Answers
The cheapest way to get from Des Moines to Appleton is to drive which costs $65 - $100 and takes 7h 4m.
The fastest way to get from Des Moines to Appleton is to fly which takes 3h 58m and costs $120 - $600.
No, there is no direct bus from Des Moines to Appleton. However, there are services departing from Des Moines and arriving at Appleton via St. Paul-Minneapolis and Wausau Transit Center. The journey, including transfers, takes approximately 13h 30m.
The distance between Des Moines and Appleton is 335 miles. The road distance is 382.4 miles.
The best way to get from Des Moines to Appleton without a car is to bus via Saint Paul which takes 13h 30m and costs $100 - $230.
It takes approximately 3h 58m to get from Des Moines to Appleton, including transfers.
Des Moines to Appleton bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Appleton is to fly which takes 3h 58m and costs $120 - $600. Alternatively, you can bus via Saint Paul, which costs $100 - $230 and takes 13h 30m.
Des Moines to Appleton bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Des Moines to Appleton is 382 miles. It takes approximately 7h 4m to drive from Des Moines to Appleton.
What companies run services between Des Moines, IA, USA and Appleton, WI, USA?
American Airlines, United Airlines, and two other airlines fly from Des Moines (DSM) to Appleton International Airport (ATW) every 2 hours. Alternatively, you can take a bus from Des Moines to Appleton via St. Paul, St. Paul-Minneapolis, Wausau Amtrak Bus Stop, and Wausau Transit Center in around 13h 30m.
- Website
- united.com
Flights from Des Moines to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 9m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $85–550
Flights from Des Moines to Appleton International Airport via Denver
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $180–900
Flights from Des Moines to Green Bay via Chicago O'Hare
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $85–550
- Website
- delta.com
Flights from Des Moines to Appleton International Airport via Detroit
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $120–700
Flights from Des Moines to Appleton International Airport via Minneapolis
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $85–550
Flights from Des Moines to Green Bay via Detroit
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $120–650
Flights from Des Moines to Green Bay via Minneapolis
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $85–550
Flights from Des Moines to Green Bay via Atlanta
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $180–900
- Website
- aa.com
Flights from Des Moines to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $85–550
Flights from Des Moines to Appleton International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $190–900
Flights from Des Moines to Appleton International Airport via Charlotte
- Ave. Duration
- 7h 29m
- When
- Tuesday
- Estimated price
- $190–900
Flights from Des Moines to Green Bay via Chicago O'Hare
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $85–550
- Website
- allegiantair.com
Flights from Des Moines to Appleton International Airport via Nashville
- Ave. Duration
- 4h 19m
- When
- Monday and Friday
- Estimated price
- $140–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $21–50
- Website
- https://www.amtrak.com/home.html
Train from St. Paul-Minneapolis to Milwaukee
- Ave. Duration
- 5h 50m
- Frequency
- 3 times a day
- Estimated price
- $80–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $23–110
- Book at
- https://www.jeffersonlines.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from St. Paul-Minneapolis to Wausau Amtrak Bus Stop
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $55–100
- Website
- https://www.amtrak.com/home.html
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 24m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Website
- https://www.amtrak.com/home.html
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from Wausau Transit Center to Appleton
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $23–26
- Schedules at
- golamers.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $23–26
- Schedules at
- golamers.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Appleton Transit Center
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $23–40
- Schedules at
- flixbus.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- $12–22
- Schedules at
- flixbus.com
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More Questions & Answers
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