There are 7 ways to get from Des Moines to Appleton by plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Appleton International Airport
best- Fly from Des Moines (DSM) to Appleton International Airport (ATW)plane DSM - ATW
3h 58m$127–644Drive 380.2 mi
cheapest- Drive from Des Moines to Appletoncar 380.2 mi
7h 4m$70–101Bus
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0123 / ...
- Take the bus from Chicago Bus Station to Appleton Transit Centerbus FlixBus 2550
12h 35m$76–139Fly to Green Bay
- Fly from Des Moines (DSM) to Green Bay (GRB)plane DSM - GRB
5h 33m$143–664Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to Appleton Amtrak Stationbus
13h 7m$85–194Bus via Saint Paul
- Take the bus from Des Moines to St. Paulbus
- Take the bus from St. Paul-Minneapolis to Wausau Amtrak Bus Stopbus
- Take the bus from Wausau Transit Center to Appletonbus
13h 30m$97–220Bus, train via Saint Paul
- Take the bus from Des Moines to St. Paulbus
- Take the train from St. Paul-Minneapolis to Milwaukeetrain
- Take the bus from Milwaukee to Appleton Amtrak Stationbus
15h 4m$106–324
Des Moines to Appleton by bus
Questions & Answers
The cheapest way to get from Des Moines to Appleton is to drive which costs $65 - $100 and takes 7h 4m.
The fastest way to get from Des Moines to Appleton is to fly which takes 3h 58m and costs $120 - $650.
No, there is no direct bus from Des Moines to Appleton. However, there are services departing from Des Moines and arriving at Appleton Transit Center via Chicago Bus Station. The journey, including transfers, takes approximately 12h 35m.
The distance between Des Moines and Appleton is 335 miles. The road distance is 382.4 miles.
The best way to get from Des Moines to Appleton without a car is to bus which takes 12h 35m and costs $75 - $140.
It takes approximately 3h 58m to get from Des Moines to Appleton, including transfers.
Des Moines to Appleton bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from Des Moines to Appleton is to fly which takes 3h 58m and costs $120 - $650. Alternatively, you can bus, which costs $75 - $140 and takes 12h 35m.
Des Moines to Appleton bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Des Moines to Appleton is 382 miles. It takes approximately 7h 4m to drive from Des Moines to Appleton.
What companies run services between Des Moines, IA, USA and Appleton, WI, USA?
American Airlines, United Airlines, and Delta fly from Des Moines (DSM) to Appleton International Airport (ATW) every 2 hours. Alternatively, you can take a bus from Des Moines to Appleton Transit Center via Chicago Bus Station in around 12h 35m.
- Website
- delta.com
Flights from Des Moines to Appleton International Airport via Detroit
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $120–700
Flights from Des Moines to Appleton International Airport via Minneapolis
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $90–600
Flights from Des Moines to Green Bay via Detroit
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $120–700
Flights from Des Moines to Green Bay via Minneapolis
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $90–600
Flights from Des Moines to Green Bay via Atlanta
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $190–900
- Website
- united.com
Flights from Des Moines to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $90–600
Flights from Des Moines to Appleton International Airport via Denver
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $180–900
Flights from Des Moines to Green Bay via Chicago O'Hare
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $90–600
- Website
- aa.com
Flights from Des Moines to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $90–600
Flights from Des Moines to Appleton International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $190–900
Flights from Des Moines to Green Bay via Chicago O'Hare
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $90–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $19–45
- Website
- https://www.amtrak.com/home.html
Train from St. Paul-Minneapolis to Milwaukee
- Ave. Duration
- 5h 50m
- Frequency
- 3 times a day
- Estimated price
- $70–170
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 7h 5m
- Frequency
- 3 times a day
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Appleton Transit Center
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $22–40
- Schedules at
- flixbus.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- $12–21
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 24m
- Frequency
- Twice daily
- Estimated price
- $29–50
- Website
- https://www.amtrak.com/home.html
Bus from St. Paul-Minneapolis to Wausau Amtrak Bus Stop
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $50–90
- Website
- https://www.amtrak.com/home.html
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $23–26
- Schedules at
- golamers.com
Bus from Wausau Transit Center to Appleton
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $23–26
- Schedules at
- golamers.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to St. Paul
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $23–110
- Book at
- https://www.jeffersonlines.com
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More Questions & Answers
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