There are 6 ways to get from Depew to Poughkeepsie by plane, train, train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Buffalo Niagara International Airport to Laguardia Airport, train
best- Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)BUF - LGA
- Take the train from 125th Street - Harlem to Poughkeepsie
4h 21m$96–463Train
cheapest- Take the train from Buffalo Depew Station to Poughkeepsie Amtrak StationEmpire Service / ...
7h 41m$52–192Drive 322.1 mi
- Drive from Depew to Poughkeepsie322.1 mi
6h 26m$59–85Fly Buffalo Niagara International Airport to John F. Kennedy International Airport, train
- Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)BUF - JFK
- Take the train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Station
4h 34m$120–524Fly Buffalo Niagara International Airport to Newark Liberty International Airport, train
- Fly from Buffalo Niagara International Airport (BUF) to Newark Liberty International Airport (EWR)BUF - EWR
- Take the train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Station
4h 58m$123–500Bus to Rochester, fly to Laguardia Airport, train
- Take the bus from Buffalo, NY to Rochester, NY
- Fly from Rochester (ROC) to Laguardia Airport (LGA)ROC - LGA
- Take the train from 125th Street - Harlem to Poughkeepsie
6h 24m$196–538
Depew to Poughkeepsie by bus and train
Questions & Answers
The cheapest way to get from Depew to Poughkeepsie is to drive which costs $55 - $85 and takes 6h 26m.
The fastest way to get from Depew to Poughkeepsie is to fly and train which takes 4h 21m and costs $95 - $470.
The distance between Depew and Poughkeepsie is 373 miles. The road distance is 324 miles.
The best way to get from Depew to Poughkeepsie without a car is to train which takes 7h 41m and costs $50 - $200.
It takes approximately 4h 21m to get from Depew to Poughkeepsie, including transfers.
Yes, the driving distance between Depew to Poughkeepsie is 324 miles. It takes approximately 6h 26m to drive from Depew to Poughkeepsie.
There are 122+ hotels available in Poughkeepsie.
What companies run services between Depew, NY, USA and Poughkeepsie, NY, USA?
Amtrak operates a train from Buffalo Depew Station to Poughkeepsie Amtrak Station 4 times a day. Tickets cost $80–190 and the journey takes 6h 35m. VIA Rail also services this route once daily.
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- Website
- delta.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $60–410
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $60–410
Flights from Rochester to Laguardia Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $50–340
- Website
- united.com
Flights from Buffalo Niagara International Airport to Newark Liberty International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $55–380
Flights from Buffalo Niagara International Airport to Newark Liberty International Airport via Washington Dulles
- Ave. Duration
- 3h 54m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $70–430
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 26m
- When
- Every day
- Estimated price
- $60–410
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport via Boston
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $85–480
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $60–410
Flights from Buffalo Niagara International Airport to Laguardia Airport via Reagan Washington
- Ave. Duration
- 3h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–470
- Phone
- 877.690.5114
- Website
- mta.info
Train from 125th Street - Harlem to Poughkeepsie
- Ave. Duration
- 1h 39m
- Frequency
- Hourly
- Estimated price
- $17–26
- Website
- https://www.mta.info/agency/metro-north-railroad
- Schedules at
- https://www.mta.info/schedules
- Off-Peak
- $17–19
- Peak
- $23–26
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Poughkeepsie Amtrak Station
- Ave. Duration
- 6h 35m
- Frequency
- 4 times a day
- Estimated price
- $80–190
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Poughkeepsie Amtrak Station
- Ave. Duration
- 1h 25m
- Frequency
- Every 2 hours
- Estimated price
- $30–75
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from Buffalo Depew Station to Poughkeepsie Amtrak Station
- Ave. Duration
- 8h 9m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- https://www.viarail.ca/en
- Economy Adult - same day booking
- $60–110
- Economy Adult - Advanced Booking
- $60–95
- Economy Escape Advanced Booking - Adult
- $50–70
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Buffalo, NY to Rochester, NY
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $20–55
- Website
- https://www.ourbus.com
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