There are 8 ways to get from Depew to Manhattan by plane, train (Amtrak), bus (Greyhound), car, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Laguardia Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane BUF - LGA
2h 15m$105–623Bus
cheapest- Take the bus from Buffalo to Port Authority Bus Terminalbus Greyhound US0205 / ...
10h 4m$57–252Train (Amtrak)
- Take the train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Stationtrain Empire Service / ...
9h 6m$122–272Drive 351.4 mi
- Drive from Depew to Manhattancar 351.4 mi
7h 10m$65–93Fly to John F. Kennedy International Airport
- Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)plane BUF - JFK
2h 14m$91–458Fly to Newark Liberty International Airport, train
- Fly from Buffalo Niagara International Airport (BUF) to Newark Liberty International Airport (EWR)plane BUF - EWR
- Take the train from Newark Airport Railroad Station to New York Penn Stationtrain
2h 18m$97–458Bus via New York Midtown (Flixbus)
- Take the bus from Buffalo to New York Midtownbus FlixBus 2686 / ...
10h 24m$57–97Train via 86 St
- Take the train from Buffalo to New York Penn Stationtrain VIA Rail
11h 6m$65–125
Depew to Manhattan by bus and train (Amtrak)
Questions & Answers
The cheapest way to get from Depew to Manhattan is to bus via New York Midtown which costs $55 - $100 and takes 10h 24m.
The fastest way to get from Depew to Manhattan is to fly which takes 2h 14m and costs $90 - $460.
No, there is no direct bus from Depew to Manhattan. However, there are services departing from Broadway & Meridian Street and arriving at Port Authority Bus Terminal via Buffalo. The journey, including transfers, takes approximately 10h 4m.
The distance between Depew and Manhattan is 305 miles. The road distance is 353.5 miles.
The best way to get from Depew to Manhattan without a car is to train which takes 9h 6m and costs $120 - $280.
It takes approximately 2h 15m to get from Depew to Manhattan, including transfers.
Depew to Manhattan bus services, operated by Greyhound USA, depart from Buffalo station.
The best way to get from Depew to Manhattan is to fly which takes 2h 15m and costs $100 - $650. Alternatively, you can train, which costs $120 - $280 and takes 9h 6m, you could also bus, which costs $55 - $260 and takes 10h 4m.
Depew to Manhattan bus services, operated by Greyhound USA, arrive at Port Authority Bus Terminal station.
Yes, the driving distance between Depew to Manhattan is 353 miles. It takes approximately 7h 10m to drive from Depew to Manhattan.
What companies run services between Depew, NY, USA and Manhattan, NY, USA?
American Airlines, Delta, and United Airlines fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA) every 3 hours. Alternatively, Amtrak operates a train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Station 4 times a day. Tickets cost $120–270 and the journey takes 8h.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $85–600
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $60–420
- Website
- united.com
Flights from Buffalo Niagara International Airport to Laguardia Airport via Washington Dulles
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $120–700
Flights from Buffalo Niagara International Airport to Newark Liberty International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $60–410
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $85–600
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $60–420
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h
- Frequency
- 4 times a day
- Estimated price
- $120–270
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 973-275-5555
- Website
- njtransit.com
Train from Newark Airport Railroad Station to New York Penn Station
- Ave. Duration
- 27 min
- Frequency
- Every 20 minutes
- Estimated price
- $15–19
- Website
- https://www.njtransit.com
- Website
- https://njtworldcup.com/
- Adult Airport
- $15–19
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from Buffalo to New York Penn Station
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.viarail.ca/en
- Economy Adult - same day booking
- $75–120
- Economy Adult - Advanced Booking
- $75–100
- Economy Escape Advanced Booking - Adult
- $60–80
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Port Authority Bus Terminal
- Ave. Duration
- 8h 5m
- Frequency
- 4 times a day
- Estimated price
- $60–130
- Website
- https://www.greyhound.com/
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Port Authority Bus Terminal
- Ave. Duration
- 8h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–250
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $55–240
- Flexible
- $100–250
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Buffalo to New York Midtown
- Ave. Duration
- 8h 25m
- Frequency
- Every 3 hours
- Estimated price
- $55–95
- Schedules at
- flixbus.com
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