There are 7 ways to get from Depew to Manhattan by plane, train (Amtrak), bus (Greyhound), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Laguardia Airport
best- Fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA)plane BUF - LGA
2h 21m$85–453Bus
cheapest- Take the bus from Buffalo to Port Authority Bus Terminalbus Greyhound US0205 / ...
10h 4m$57–252Train (Amtrak)
- Take the train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Stationtrain Empire Service / ...
9h 6m$232–372Drive 351.4 mi
- Drive from Depew to Manhattancar 351.4 mi
7h 11m$61–87Fly to John F. Kennedy International Airport
- Fly from Buffalo Niagara International Airport (BUF) to John F. Kennedy International Airport (JFK)plane BUF - JFK
2h 11m$66–268Fly to Newark Liberty International Airport
- Fly from Buffalo Niagara International Airport (BUF) to Newark Liberty International Airport (EWR)plane BUF - EWR
2h 29m$74–299Train via Penn Station
- Take the train from Buffalo to New York Penn Stationtrain VIA Rail
9h 42m$112–282
Depew to Manhattan by bus and train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Depew to Manhattan is to drive which costs $60 - $90 and takes 7h 11m.
The fastest way to get from Depew to Manhattan is to fly which takes 2h 11m and costs $65 - $270.
No, there is no direct bus from Depew to Manhattan. However, there are services departing from Broadway & Meridian Street and arriving at Port Authority Bus Terminal via Buffalo. The journey, including transfers, takes approximately 10h 4m.
No, there is no direct train from Depew station to Manhattan station. However, there are services departing from Buffalo Depew Station and arriving at Ny Moynihan Train Hall At Penn Station via . The journey, including transfers, takes approximately 9h 6m.
The distance between Depew and Manhattan is 305 miles. The road distance is 353.5 miles.
The best way to get from Depew to Manhattan without a car is to train which takes 9h 6m and costs $230 - $380.
It takes approximately 2h 21m to get from Depew to Manhattan, including transfers.
Depew to Manhattan bus services, operated by Greyhound USA, depart from Buffalo station.
Depew to Manhattan train services, operated by Amtrak, depart from Buffalo Depew Station.
The best way to get from Depew to Manhattan is to fly which takes 2h 21m and costs $85 - $460. Alternatively, you can train, which costs $230 - $380 and takes 9h 6m, you could also bus, which costs $55 - $260 and takes 10h 4m.
What companies run services between Depew, NY, USA and Manhattan, NY, USA?
American Airlines, Delta, and United Airlines fly from Buffalo Niagara International Airport (BUF) to Laguardia Airport (LGA) every 3 hours. Alternatively, Amtrak operates a train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Station 4 times a day. Tickets cost $230–370 and the journey takes 8h.
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $65–430
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $35–230
Flights from Buffalo Niagara International Airport to Newark Liberty International Airport via Detroit
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $55–320
- Website
- united.com
Flights from Buffalo Niagara International Airport to Laguardia Airport via Washington Dulles
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $80–480
Flights from Buffalo Niagara International Airport to Newark Liberty International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- $35–250
Flights from Buffalo Niagara International Airport to Newark Liberty International Airport via Washington Dulles
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $45–280
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Laguardia Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $65–430
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport via Boston
- Ave. Duration
- 3h 50m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $45–270
- Website
- jetblue.com
Flights from Buffalo Niagara International Airport to John F. Kennedy International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $35–230
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Buffalo Depew Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 8h
- Frequency
- 4 times a day
- Estimated price
- $230–370
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Buffalo to New York Penn Station
- Ave. Duration
- 8h 36m
- Frequency
- Once daily
- Estimated price
- $110–280
- Website
- VIA Rail
- Escape
- $110–250
- Business
- $150–270
- Business Plus
- $160–280
- Economy
- $120–260
- Economy Plus
- $140–270
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Buffalo to Port Authority Bus Terminal
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $75–120
- Website
- Greyhound
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo to Port Authority Bus Terminal
- Ave. Duration
- 8h 30m
- Frequency
- 3 times a day
- Estimated price
- $55–250
- Website
- Trailways
- Schedules at
- Trailways
- Saver
- $55–240
- Flexible
- $100–250
Want to know more about travelling around United States
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Booking & Getting There
Depew to Manhattan bus services, operated by Greyhound USA, arrive at Port Authority Bus Terminal station.
Depew to Manhattan train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Depew to Manhattan is 353 miles. It takes approximately 7h 11m to drive from Depew to Manhattan.
There are 3974+ hotels available in Manhattan.