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How to get fromDepew to Clevelandby train (Amtrak), bus (Greyhound), car or plane

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There are 4 ways to get from Depew to Cleveland by train (Amtrak), bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Buffalo Depew Station to Cleveland AmtraktrainLake Shore Limited
    4h 20m
    $32–82

  2. Line 2 bus, bus

    cheapest
    1. Take the bus from Broadway & Meridian Street to Ellicott Street & MTC Staticbus2
    2. Take the bus from Buffalo to Cleveland Bus StationbusGreyhound US0170
    5h 39m
    $29–67

  3. Drive 193.5 mi

    1. Drive from Depew to Clevelandcar193.5 mi
    3h 25m
    $36–51

  4. Fly

    1. Fly from Buffalo Niagara International Airport (BUF) to Cleveland-Hopkins International Airport (CLE)planeBUF - CLE
    4h 20m
    $130–723

Depew to Cleveland by bus and train (Amtrak)

Calendar14Weekly Services
Duration4h 20mAverage Duration
Ticket$32Cheapest Price
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Questions & Answers

What companies run services between Depew, NY, USA and Cleveland, OH, USA?

Amtrak operates a train from Buffalo Depew Station to Cleveland Amtrak twice daily. Tickets cost $30–80 and the journey takes 3h 14m. Alternatively, you can take a bus from Broadway & Meridian Street to Cleveland Bus Station via Buffalo in around 5h 39m.

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