There are 8 ways to get from Denver to Siena by plane, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Denver (DEN) to Florence Peretola Airport (FLR)plane DEN - FLR
- Take the train from Firenze S.M.N. to Sienatrain
17h 8m€352–880Fly to Pisa International Airport, train
cheapest- Fly from Denver (DEN) to Pisa International Airport (PSA)plane DEN - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
17h 46m€336–1,139Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Denver (DEN) to Bologna Guglielmo Marconi Airport (BLQ)plane DEN - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
17h 38m€420–1,055Fly to Fiumicino International Airport, train
- Fly from Denver (DEN) to Fiumicino International Airport (FCO)plane DEN - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
17h 32m€381–1,015Fly to Venice Marco Polo Airport, train
- Fly from Denver (DEN) to Venice Marco Polo Airport (VCE)plane DEN - VCE
- Take the train from Venezia Mestre to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
19h 30m€471–860Fly to Verona Villafranca Airport, train
- Fly from Denver (DEN) to Verona Villafranca Airport (VRN)plane DEN - VRN
- Take the train from Verona Porta Nuova to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
19h 47m€406–1,395Fly to Perugia Sant'Egidio Airport, bus
- Fly from Denver (DEN) to Perugia Sant'Egidio Airport (PEG)plane DEN - PEG
- Take the bus from Perugia to Sienabus
37h 19m€428–1,526Fly to Raffaello Sanzio Airport, train
- Fly from Denver (DEN) to Raffaello Sanzio Airport (AOI)plane DEN - AOI
- Take the train from Ancona to Bologna Centraletrain
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
20h 13m€483–1,718
Denver (DEN) to Florence Peretola Airport (FLR) flights
Questions & Answers
The cheapest way to get from Denver to Siena is to fly and train which costs €350 - €900 and takes 17h 8m.
The fastest way to get from Denver to Siena is to fly and train which takes 17h 8m and costs €350 - €900.
The distance between Denver and Siena is 8849 km.
It takes approximately 17h 8m to get from Denver to Siena, including transfers.
Siena is 8h ahead of Denver. It is currently 4:10 AM in Denver and 12:10 PM in Siena.
There are 2516+ hotels available in Siena.
What companies run services between Denver, CO, USA and Siena, Italy?
There is no direct connection from Denver to Siena. However, you can take the train to Denver Airport Station, walk to Denver (DEN) airport, fly to Florence Peretola Airport (FLR), walk to Florence Airport (FLR), take the vehicle to Alamanni - Stazione Smn, walk to Firenze S.M.N., then take the train to Siena. Alternatively, you can take the train to Denver Airport Station, walk to Denver (DEN) airport, fly to Pisa International Airport (PSA), walk to Pisa Aeroporto, take the train to Pisa Centrale, take the train to Empoli, then take the train to Siena.
- Website
- lufthansa.com
Flights from Denver to Florence Peretola Airport via Munich
- Ave. Duration
- 12h 17m
- When
- Every day
- Estimated price
- €360–1,400
Flights from Denver to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 14h 52m
- When
- Every day
- Estimated price
- €350–1,400
Flights from Denver to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 12h 55m
- When
- Every day
- Estimated price
- €370–1,300
Flights from Denver to Pisa International Airport via Frankfurt
- Ave. Duration
- 17h 2m
- When
- Every day
- Estimated price
- €310–1,300
Flights from Denver to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 12h 20m
- When
- Every day
- Estimated price
- €300–1,200
Flights from Denver to Bologna Guglielmo Marconi Airport via Frankfurt
- Ave. Duration
- 12h 20m
- When
- Every day
- Estimated price
- €330–1,200
Flights from Denver to Bologna Guglielmo Marconi Airport via Fiumicino International Airport
- Ave. Duration
- 12h 55m
- When
- Every day
- Estimated price
- €320–1,200
Flights from Denver to Fiumicino International Airport
- Ave. Duration
- 10h 30m
- When
- Every day
- Estimated price
- €260–950
Flights from Denver to Fiumicino International Airport via Frankfurt
- Ave. Duration
- 12h 30m
- When
- Every day
- Estimated price
- €260–1,100
Flights from Denver to Fiumicino International Airport via Munich
- Ave. Duration
- 14h 50m
- When
- Every day
- Estimated price
- €290–1,100
Flights from Denver to Venice Marco Polo Airport via Frankfurt
- Ave. Duration
- 12h
- When
- Every day
- Estimated price
- €310–1,100
Flights from Denver to Venice Marco Polo Airport via Munich
- Ave. Duration
- 12h 20m
- When
- Every day
- Estimated price
- €290–1,100
Flights from Denver to Venice Marco Polo Airport via Fiumicino International Airport
- Ave. Duration
- 12h 40m
- When
- Every day
- Estimated price
- €310–1,100
Flights from Denver to Verona Villafranca Airport via Frankfurt
- Ave. Duration
- 13h 7m
- When
- Every day
- Estimated price
- €350–1,400
Flights from Denver to Verona Villafranca Airport via Munich
- Ave. Duration
- 16h 10m
- When
- Every day
- Estimated price
- €360–1,400
Flights from Denver to Raffaello Sanzio Airport via Munich
- Ave. Duration
- 12h 5m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €430–1,500
Flights from Denver to Raffaello Sanzio Airport via Frankfurt, Munich
- Ave. Duration
- 14h 50m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €470–1,700
Flights from Denver to Raffaello Sanzio Airport via London Heathrow, Munich
- Ave. Duration
- 14h 55m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €430–1,500
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–10
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–13
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- Every 3 hours
- Estimated price
- €30–55
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
Train from Ancona to Bologna Centrale
- Ave. Duration
- 2h 41m
- Frequency
- Every 3 hours
- Estimated price
- €25–40
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- 4 times a day
- Estimated price
- €11–18
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- Trenitalia
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Perugia to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- €7–13
- Website
- Flixbus
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Getting to Rome from the airport
Read the travel guide





