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How to get fromDenver to Port Isabelby plane, bus (Greyhound), car, bus or bus (Greyhound, Flixbus)

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There are 9 ways to get from Denver to Port Isabel by plane, bus (Greyhound), car, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Denver to Brownsville-South Padre Island International Airport

    best
    1. Fly from Denver (DEN) to Brownsville-South Padre Island International Airport (BRO)planeDEN - BRO
    8h 7m
    $132–612

  2. Bus via Dallas

    1. Take the bus from Denver Union Station to Dallas Bus StationbusGreyhound US1144
    2. Take the bus from Dallas to BrownsvillebusDallas
    33h 14m
    $215–369

  3. Drive 1,213.9 mi

    1. Drive from Denver to Port Isabelcar1,213.9 mi
    19h 49m
    $222–320

  4. Bus to Colorado Springs Airport, fly to Brownsville-South Padre Island International Airport

    1. Take the bus from Denver to Colorado Springsbus
    2. Fly from Colorado Springs Airport (COS) to Brownsville-South Padre Island International Airport (BRO)planeCOS - BRO
    10h 7m
    $160–611

  5. Fly Denver to Mcallen Miller International Airport, bus

    1. Fly from Denver (DEN) to Mcallen Miller International Airport (MFE)planeDEN - MFE
    2. Take the bus from McAllen Central Station to Brownsvillebus
    10h 9m
    $207–824

  6. Fly Denver to Rio Grande Valley International Airport, bus

    1. Fly from Denver (DEN) to Rio Grande Valley International Airport (HRL)planeDEN - HRL
    2. Take the bus from Harlingen Bus Station to Brownsvillebus
    10h 49m
    $144–544

  7. Fly Denver to Corpus Christi International Airport, bus

    1. Fly from Denver (DEN) to Corpus Christi International Airport (CRP)planeDEN - CRP
    2. Take the bus from Robstown Station to Brownsville Bus Stationbus
    9h 45m
    $182–567

  8. Bus

    1. Take the bus from Denver Union Station to Dallas Bus StationbusGreyhound US1144
    2. Take the bus from Dallas Bus Station to La Plaza at BrownsvillebusFlixBus US1164 / ...
    37h 25m
    $190–359

  9. Bus via Ciudad Juárez

    1. Take the bus from Denver to El Paso, TXbusDenver to El Paso
    2. Take the bus from Ciudad Juárez to Matamorosbus
    42h 49m
    $234–382

Denver (DEN) to Brownsville-South Padre Island International Airport (BRO) flights

Calendar52Weekly Planes
Duration5h 30mAverage Duration
Ticket$127Cheapest Price
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Questions & Answers

What companies run services between Denver, CO, USA and Port Isabel, TX, USA?

United Airlines and American Airlines fly from Denver (DEN) to Brownsville-South Padre Island International Airport (BRO) every 4 hours. Alternatively, you can take a bus from Denver Union Station to Las Palmas Port Isabel via Dallas Bus Station, Union Streetcar Station, Bishop Arts Station, Dallas, and La Plaza at Brownsville in around 33h 14m.

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