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How to get fromDenver to Port Isabelby plane, bus (Greyhound), car, bus or bus (Greyhound, Flixbus)

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There are 9 ways to get from Denver to Port Isabel by plane, bus (Greyhound), car, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Denver to Brownsville-South Padre Island International Airport

    best
    1. Fly from Denver (DEN) to Brownsville-South Padre Island International Airport (BRO)plane plane DEN - BRO
    8h 11m
    $142–662

  2. Bus via Dallas

    1. Take the bus from Denver Union Station to Dallas Bus Stationbus bus Greyhound US1144
    2. Take the bus from Dallas to Brownsvillebus bus Dallas
    33h 31m
    $185–320

  3. Drive 1,213.9 mi

    1. Drive from Denver to Port Isabelcar car 1,213.9 mi
    19h 52m
    $222–320

  4. Bus to Colorado Springs Airport, fly to Brownsville-South Padre Island International Airport

    1. Take the bus from Denver to Colorado Springsbus bus
    2. Fly from Colorado Springs Airport (COS) to Brownsville-South Padre Island International Airport (BRO)plane plane COS - BRO
    9h 55m
    $220–911

  5. Fly Denver to Mcallen Miller International Airport, bus

    1. Fly from Denver (DEN) to Mcallen Miller International Airport (MFE)plane plane DEN - MFE
    2. Take the bus from McAllen Central Station to Brownsvillebus bus
    10h 33m
    $157–574

  6. Fly Denver to Rio Grande Valley International Airport, bus

    1. Fly from Denver (DEN) to Rio Grande Valley International Airport (HRL)plane plane DEN - HRL
    2. Take the bus from Harlingen Bus Station to Brownsvillebus bus
    10h 39m
    $149–564

  7. Fly Denver to Corpus Christi International Airport, bus

    1. Fly from Denver (DEN) to Corpus Christi International Airport (CRP)plane plane DEN - CRP
    2. Take the bus from Robstown Station to Brownsville Bus Stationbus bus
    9h 42m
    $182–597

  8. Bus

    1. Take the bus from Denver Union Station to Dallas Bus Stationbus bus Greyhound US1144
    2. Take the bus from Dallas Bus Station to La Plaza at Brownsvillebus bus FlixBus US1164 / ...
    37h 30m
    $154–314

  9. Bus via Ciudad Juárez

    1. Take the bus from Denver to El Paso, TXbus bus Denver to El Paso
    2. Take the bus from Ciudad Juárez to Matamorosbus bus
    42h 49m
    $244–392

Denver (DEN) to Brownsville-South Padre Island International Airport (BRO) flights

Calendar48Weekly Planes
Duration5h 25mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

What companies run services between Denver, CO, USA and Port Isabel, TX, USA?

United Airlines and American Airlines fly from Denver (DEN) to Brownsville-South Padre Island International Airport (BRO) every 4 hours. Alternatively, you can take a bus from Denver Union Station to Las Palmas Port Isabel via Dallas Bus Station, Bachman Station, St Paul Station, Elm @ Ervay - W - Ns, Jefferson @ Marsalis - W - Ns, Dallas, and La Plaza at Brownsville in around 33h 31m.

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