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How to get fromDenver to Buffaloby plane, train (Amtrak), bus (Greyhound), car or bus (Flixbus)

Find Transport to Buffalo

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There are 5 ways to get from Denver to Buffalo by plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Denver (DEN) to Buffalo Niagara International Airport (BUF)planeDEN - BUF
    5h 59m
    $364–1,690

  2. Bus

    cheapest
    1. Take the bus from Denver Union Station to Chicago Bus Stationbus
    2. Take the bus from Chicago Bus Station to Cleveland Bus Stationbus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus
    32h 55m
    $139–449

  3. Train (Amtrak)

    1. Take the train from Denver to Chicago Union StationtrainCalifornia Zephyr
    2. Take the train from Chicago Union Station to Buffalo Depew StationtrainLake Shore Limited
    31h 24m
    $205–615

  4. Drive 1,517.8 mi

    1. Drive from Denver to Buffalocar1,517.8 mi
    24h 26m
    $277–401

  5. Bus via Indianapolis

    1. Take the bus from Denver to Indianapolis Union Stationbus
    2. Take the bus from Indianapolis to Pittsburgh Intermodal Stationbus
    3. Take the bus from Pittsburgh to Buffalobus
    38h 29m
    $258–613

Denver to Buffalo by train (Amtrak)

Calendar7Weekly Trains
Duration31h 24mAverage Duration
Ticket$205Cheapest Price
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Questions & Answers

What companies run services between Denver, CO, USA and Buffalo, NY, USA?

United Airlines, Southwest Airlines, and Delta fly from Denver (DEN) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a train from Denver to Buffalo via Chicago Union Station and Buffalo Depew Station in around 31h 24m.

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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