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There are 9 ways to get from Delaware to South Carolina by train, plane, night bus, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Philadelphia, fly to Greenville/Spartanburg  •  4 h 1 min

  1. Take the train from Wilmington Amtrak to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Greenville/Spartanburg (GSP) PHL - GSP

$251 - $743

Cheapest option

Bus  •  12 h 50 min

  1. Take the bus from Wilmington, De to Richmond, Va
  2. Take the bus from Richmond, Va to Fayetteville, Nc
  3. Take the bus from Fayetteville, Nc to Florence, Sc

$66 - $161

7 alternative options

Train to Philadelphia, fly to Columbia  •  4 h 5 min

  1. Take the train from Wilmington Amtrak to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Columbia (CAE) PHL - CAE

$295 - $1,028

Train to Philadelphia, fly to Charlotte  •  4 h 11 min

  1. Take the train from Wilmington Amtrak to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Charlotte (CLT) PHL - CLT

$221 - $538

Train to Philadelphia, fly to Charleston  •  4 h 54 min

  1. Take the train from Wilmington Amtrak to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Charleston (CHS) PHL - CHS

$223 - $851

Night bus to Salisbury, fly to Charlotte  •  6 h 10 min

  1. Take the night bus from Dover to Salisbury, Md
  2. Fly from Salisbury (SBY) to Charlotte (CLT) SBY - CLT

$227 - $793

Train to Baltimore, fly to Charleston  •  6 h 29 min

  1. Take the train from Wilmington Amtrak to BWI Airport Amtrak
  2. Fly from Baltimore (BWI) to Charleston (CHS) BWI - CHS

$216 - $816

Train  •  9 h 47 min

  1. Take the train from Wilmington Amtrak to Florence Amtrak Palmetto / ...

$75 - $220

Drive  •  8 h 39 min

  1. Drive from Wilmington to Florence 516.4 miles

$50 - $75

Questions & Answers

The cheapest way to get from Delaware to South Carolina is to drive which costs $50 - $75 and takes 8 h 39 min.

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The quickest way to get from Delaware to South Carolina is to train and fly which costs $250 - $750 and takes 4 h 1 min.

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No, there is no direct bus from Delaware to South Carolina. However, there are services departing from Wilmington, De and arriving at Florence, Sc via Richmond, Va and Fayetteville, Nc. The journey, including transfers, takes approximately 12 h 50 min.

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Yes, there is a direct train departing from Wilmington Amtrak and arriving at Florence Amtrak. Services depart twice daily, and operate every day. The journey takes approximately 9 h 47 min.

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The distance between Delaware and South Carolina is 448 miles. The road distance is 516.4 miles.

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The best way to get from Delaware to South Carolina without a car is to train which takes 9 h 47 min and costs $75 - $220.

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It takes approximately 4 h 1 min to get from Delaware to South Carolina, including transfers.

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Delaware to South Carolina bus services, operated by Greyhound USA, depart from Wilmington, De station.

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Delaware to South Carolina train services, operated by Amtrak, depart from Wilmington Amtrak station.

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The best way to get from Delaware to South Carolina is to train which takes 9 h 47 min and costs $75 - $220. Alternatively, you can bus, which costs $65 - $170 and takes 12 h 50 min.

Mode details

Map of how to get from Delaware to South Carolina.
Launch map view
  • Distance: 447.9 miles
  • Duration: 4 h 1 min

What companies run services between Delaware, USA and South Carolina, USA?

Amtrak operates a train from Wilmington to Florence twice daily. Tickets cost $75 - $220 and the journey takes 9 h 47 min. Alternatively, you can take a bus from Wilmington to Florence via Richmond, Va and Fayetteville, Nc in around 12 h 50 min.

Airlines
American Airlines
Website
aa.com
Flights from Philadelphia to Greenville/Spartanburg
Ave. Duration
1 h 49 min
When
Every day
Estimated price
$200 - $950
Flights from Philadelphia to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$200 - $950
Flights from Philadelphia to Columbia
Ave. Duration
1 h 57 min
When
Every day
Estimated price
$420 - $1,600
Flights from Philadelphia to Columbia via Charlotte
Ave. Duration
3 h 49 min
When
Every day
Estimated price
$420 - $1,600
Flights from Philadelphia to Charlotte
Ave. Duration
1 h 48 min
When
Every day
Estimated price
$190 - $650
Flights from Philadelphia to Charlotte via Charlottesville
Ave. Duration
3 h 14 min
When
Every day
Estimated price
$190 - $650
Flights from Philadelphia to Charlotte via Newport News
Ave. Duration
3 h 15 min
When
Every day
Estimated price
$190 - $650
Flights from Philadelphia to Charlotte via Charleston
Ave. Duration
3 h 26 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $650
Flights from Philadelphia to Charlotte via Harrisburg
Ave. Duration
3 h 32 min
When
Every day
Estimated price
$190 - $650
Flights from Philadelphia to Charleston
Ave. Duration
2 h 1 min
When
Every day
Estimated price
$250 - $1,300
Flights from Philadelphia to Charleston via Charlotte
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$250 - $1,300
Flights from Philadelphia to Charleston via Reagan Washington
Ave. Duration
4 h 2 min
When
Monday to Saturday
Estimated price
$250 - $1,300
Flights from Salisbury to Charlotte
Ave. Duration
1 h 43 min
When
Every day
Estimated price
$120 - $650
Flights from Salisbury to Charlotte via Philadelphia
Ave. Duration
4 h 16 min
When
Every day
Estimated price
$140 - $700
Flights from Baltimore to Charleston via Charlotte
Ave. Duration
3 h 38 min
When
Every day
Estimated price
$190 - $1,100
United Airlines
Website
united.com
Flights from Philadelphia to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3 h 52 min
When
Every day
Estimated price
$290 - $1,000
Flights from Philadelphia to Columbia via Washington Dulles
Ave. Duration
3 h 47 min
When
Every day
Estimated price
$420 - $1,800
Flights from Philadelphia to Charlotte via Washington Dulles
Ave. Duration
3 h 34 min
When
Every day
Estimated price
$190 - $1,000
Flights from Philadelphia to Charleston via Washington Dulles
Ave. Duration
3 h 52 min
When
Every day
Estimated price
$260 - $1,800
Southwest Airlines
Website
southwest.com
Flights from Philadelphia to Greenville/Spartanburg via Atlanta
Ave. Duration
4 h
When
Monday to Friday
Estimated price
$250 - $800
Flights from Baltimore to Charleston
Ave. Duration
1 h 37 min
When
Every day
Estimated price
$190 - $1,100
Delta
Website
delta.com
Flights from Philadelphia to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$200 - $750
Flights from Philadelphia to Columbia via Atlanta
Ave. Duration
4 h 7 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$440 - $1,700
Flights from Philadelphia to Charleston via Atlanta
Ave. Duration
4 h 14 min
When
Every day
Estimated price
$260 - $1,300
Flights from Baltimore to Charleston via Atlanta
Ave. Duration
3 h 46 min
When
Every day
Estimated price
$190 - $1,000
Frontier Airlines
Website
flyfrontier.com
Flights from Philadelphia to Charlotte
Ave. Duration
1 h 48 min
When
Monday, Wednesday, Friday and Saturday
Estimated price
$110 - $800
Flights from Philadelphia to Charleston
Ave. Duration
2 h 7 min
When
Monday, Wednesday, Friday and Saturday
Estimated price
$120 - $600
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Wilmington Amtrak to Philadelphia 30th Street Station
Ave. Duration
19 min
Frequency
Hourly
Estimated price
$50 - $150
Website
amtrak.com
Business Seat
$50 - $140
First Class Seat
$110 - $150
Train from Wilmington Amtrak to BWI Airport Amtrak
Ave. Duration
55 min
Frequency
Hourly
Estimated price
$70 - $200
Website
amtrak.com
Business Seat
$70 - $170
First Class Seat
$140 - $200
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Wilmington Amtrak to Florence Amtrak
Ave. Duration
9 h 47 min
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$130 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Night bus from Dover to Salisbury, Md
Ave. Duration
1 h 35 min
Frequency
Once daily
Estimated price
$12 - $28
Website
greyhound.com
Economy
$12 - $18
Flexible
$22 - $28
Bus from Wilmington, De to Richmond, Va
Ave. Duration
4 h 55 min
Frequency
Twice daily
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $40
Flexible
$45 - $65
Bus from Richmond, Va to Fayetteville, Nc
Ave. Duration
4 h 20 min
Frequency
Every 2 hours
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $45
Flexible
$45 - $65
Bus from Fayetteville, Nc to Florence, Sc
Ave. Duration
1 h 35 min
Frequency
5 times a day
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $22
Flexible
$26 - $35

Want to know more about travelling around United States

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More Questions & Answers

The quickest flight from Philadelphia Airport to Greenville/Spartanburg Airport is the direct flight which takes 1 h 44 min.

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Delaware to South Carolina bus services, operated by Greyhound USA, arrive at Florence, Sc station.

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Delaware to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak station.

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Yes, the driving distance between Delaware to South Carolina is 516 miles. It takes approximately 8 h 39 min to drive from Delaware to South Carolina.

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Southwest Airlines, United Airlines, Delta and American Airlines offer flights from Philadelphia Airport to Greenville/Spartanburg Airport.

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Book your Delaware to South Carolina train tickets online with Rome2rio.

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Book your Delaware to South Carolina bus tickets online with Greyhound, Greyhound and Greyhound.

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There are 16+ hotels available in South Carolina. Prices start at $52 USD per night.

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