• Our partners include:

  • Greyhound USA
  • VIA Rail
  • Amtrak
  • Acela Express
  • Megabus
  • SuperShuttle
  • Booking.com
  • Skyscanner
  • Airbnb
  • Expedia

There are 8 ways to get from Delaware to South Carolina by train, plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Philadelphia, fly to Greenville/Spartanburg  •  4h 8m

  1. Take the train from Wilmington Amtrak Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Greenville/Spartanburg (GSP) PHL - GSP

$204 - $743

Cheapest option

Bus  •  12h 50m

  1. Take the bus from Wilmington, De to Richmond, Va
  2. Take the bus from Richmond, Va to Fayetteville, Nc
  3. Take the bus from Fayetteville, Nc to Florence, Sc

$66 - $161

6 alternative options

Train to Philadelphia, fly to Charleston  •  5h 5m

  1. Take the train from Wilmington Amtrak Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Charleston (CHS) PHL - CHS

$176 - $851

Train to Philadelphia, fly to Columbia  •  5h 20m

  1. Take the train from Wilmington Amtrak Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Columbia (CAE) PHL - CAE

$226 - $1,000

Train to Philadelphia, fly to Charlotte, bus  •  6h 34m

  1. Take the train from Wilmington Amtrak Station to Philadelphia 30th Street Station
  2. Fly from Philadelphia (PHL) to Charlotte (CLT) PHL - CLT
  3. Take the bus from Transit Center- Bay X to White Street Park and Ride

$105 - $456

Train to Baltimore, fly to Charleston  •  6h 40m

  1. Take the train from Wilmington Amtrak Station to BWI Marshall Airport Amtrak Station
  2. Fly from Baltimore (BWI) to Charleston (CHS) BWI - CHS

$216 - $816

Train  •  9h 47m

  1. Take the train from Wilmington Amtrak Station to Florence Amtrak Station Palmetto / ...

$75 - $220

Drive  •  8h 39m

  1. Drive from Wilmington to Florence 516.4 miles

$50 - $75

Questions & Answers

The cheapest way to get from Delaware to South Carolina is to drive which costs $50 - $75 and takes 8h 39m.

More details

The quickest way to get from Delaware to South Carolina is to train and fly which costs $200 - $750 and takes 4h 8m.

More details

No, there is no direct bus from Delaware to South Carolina. However, there are services departing from Wilmington, De and arriving at Florence, Sc via Richmond, Va and Fayetteville, Nc. The journey, including transfers, takes approximately 12h 50m.

More details

Yes, there is a direct train departing from Wilmington Amtrak Station station and arriving at Florence Amtrak Station station. Services depart twice daily, and operate every day. The journey takes approximately 9h 47m.

More details

The distance between Delaware and South Carolina is 448 miles. The road distance is 516.4 miles.

Get driving directions

The best way to get from Delaware to South Carolina without a car is to train which takes 9h 47m and costs $75 - $220.

More details

It takes approximately 4h 8m to get from Delaware to South Carolina, including transfers.

More details

Delaware to South Carolina bus services, operated by Greyhound USA, depart from Wilmington, De station.

More details

Delaware to South Carolina train services, operated by Amtrak, arrive at Wilmington Amtrak Station.

More details

The best way to get from Delaware to South Carolina is to train which takes 9h 47m and costs $75 - $220. Alternatively, you can bus, which costs $65 - $170 and takes 12h 50m.

Mode details

Map of how to get from Delaware to South Carolina.
Launch map view
  • Distance: 447.9 miles
  • Duration: 4h 8m

What companies run services between Delaware, USA and South Carolina, USA?

Amtrak operates a train from Wilmington to Florence twice daily. Tickets cost $75 - $220 and the journey takes 9h 47m. Alternatively, you can take a bus from Wilmington to Florence via Richmond, Va and Fayetteville, Nc in around 12h 50m.

Airlines
American Airlines
Website
aa.com
Flights from Philadelphia to Greenville/Spartanburg
Ave. Duration
1h 51m
When
Every day
Estimated price
$200 - $950
Flights from Philadelphia to Greenville/Spartanburg via Reagan Washington
Ave. Duration
3h 41m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $950
Flights from Philadelphia to Greenville/Spartanburg via Charlotte
Ave. Duration
3h 58m
When
Every day
Estimated price
$200 - $950
Flights from Philadelphia to Charleston
Ave. Duration
2h 6m
When
Every day
Estimated price
$250 - $1,300
Flights from Philadelphia to Charleston via Reagan Washington
Ave. Duration
4h 14m
When
Every day
Estimated price
$250 - $1,300
Flights from Philadelphia to Charleston via Charlotte
Ave. Duration
4h 12m
When
Every day
Estimated price
$250 - $1,300
Flights from Philadelphia to Columbia
Ave. Duration
1h 56m
When
Every day
Estimated price
$420 - $1,600
Flights from Philadelphia to Columbia via Charlotte
Ave. Duration
4h 2m
When
Every day
Estimated price
$420 - $1,600
Flights from Philadelphia to Charlotte
Ave. Duration
1h 52m
When
Every day
Estimated price
$190 - $650
Flights from Philadelphia to Charlotte via Newport News
Ave. Duration
3h 8m
When
Every day
Estimated price
$190 - $650
Flights from Philadelphia to Charlotte via Charleston
Ave. Duration
3h 20m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $650
Flights from Philadelphia to Charlotte via Charlottesville
Ave. Duration
3h 27m
When
Every day
Estimated price
$190 - $650
Flights from Philadelphia to Charlotte via Greensboro/High Point
Ave. Duration
3h 30m
When
Every day
Estimated price
$190 - $650
Flights from Philadelphia to Charlotte via Raleigh/Durham
Ave. Duration
3h 31m
When
Monday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $650
Flights from Philadelphia to Charlotte via Harrisburg
Ave. Duration
3h 37m
When
Every day
Estimated price
$190 - $650
Flights from Baltimore to Charleston via Charlotte
Ave. Duration
3h 42m
When
Every day
Estimated price
$190 - $1,100
Flights from Baltimore to Charleston via Philadelphia
Ave. Duration
4h 1m
When
Monday, Thursday, Friday and Sunday
Estimated price
$190 - $1,100
Delta
Website
delta.com
Flights from Philadelphia to Greenville/Spartanburg via Atlanta
Ave. Duration
4h 27m
When
Every day
Estimated price
$200 - $750
Flights from Philadelphia to Charleston via Atlanta
Ave. Duration
4h 24m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,300
Flights from Philadelphia to Columbia via Atlanta
Ave. Duration
4h 25m
When
Every day
Estimated price
$440 - $1,700
Flights from Baltimore to Charleston via Atlanta
Ave. Duration
4h 8m
When
Every day
Estimated price
$190 - $1,000
Southwest Airlines
Website
southwest.com
Flights from Baltimore to Charleston
Ave. Duration
1h 40m
When
Every day
Estimated price
$190 - $1,100
Frontier Airlines
Website
flyfrontier.com
Flights from Philadelphia to Charleston
Ave. Duration
2h 12m
When
Wednesday and Saturday
Estimated price
$120 - $600
Flights from Philadelphia to Charlotte
Ave. Duration
1h 59m
When
Monday, Wednesday, Friday and Sunday
Estimated price
$110 - $800
Train operators
Amtrak Acela Express

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Acela Express
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Wilmington Amtrak Station to Philadelphia 30th Street Station
Ave. Duration
19m
Frequency
Hourly
Estimated price
$50 - $150
Website
amtrak.com
Business Seat
$50 - $140
First Class Seat
$110 - $150
Train from Wilmington Amtrak Station to BWI Marshall Airport Amtrak Station
Ave. Duration
1h 2m
Frequency
Hourly
Estimated price
$70 - $200
Website
amtrak.com
Business Seat
$70 - $170
First Class Seat
$140 - $200
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Wilmington Amtrak Station to Florence Amtrak Station
Ave. Duration
9h 47m
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$130 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Bus operators
Charlotte Area Transit System
Phone
+1 704-336-7433
Email
telltransit@charlottenc.gov
Website
charlottenc.gov
Bus from Transit Center- Bay X to White Street Park and Ride
Ave. Duration
1h 12m
Frequency
3 times a day
Estimated price
$3 - $5
Schedules at
charlottenc.gov
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Wilmington, De to Richmond, Va
Ave. Duration
4h 55m
Frequency
Twice daily
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $40
Flexible
$45 - $65
Bus from Richmond, Va to Fayetteville, Nc
Ave. Duration
4h 20m
Frequency
Every 2 hours
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $45
Flexible
$45 - $65
Bus from Fayetteville, Nc to Florence, Sc
Ave. Duration
1h 35m
Frequency
5 times a day
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $22
Flexible
$26 - $35

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

The quickest flight from Philadelphia Airport to Greenville/Spartanburg Airport is the direct flight which takes 1h 51m.

Search flights

Delaware to South Carolina bus services, operated by Greyhound USA, arrive at Florence, Sc station.

More details

Delaware to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak Station.

More details

Yes, the driving distance between Delaware to South Carolina is 516 miles. It takes approximately 8h 39m to drive from Delaware to South Carolina.

Get driving directions

Delta and American Airlines offer flights from Philadelphia Airport to Greenville/Spartanburg Airport.

Search flights

Book your Delaware to South Carolina train tickets online with Rome2rio.

Search and book

Book your Delaware to South Carolina bus tickets online with Greyhound, Greyhound and Greyhound.

Search and book

There are 19+ hotels available in South Carolina. Prices start at $49 USD per night.

More details