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How to get fromDefiance to St. Louisby taxi, plane, bus, train (Amtrak), car or train

Find Transport to St. Louis

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There are 5 ways to get from Defiance to St. Louis by taxi, plane, bus, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly

    best
    1. Take the taxi from Defiance to Fort Wayne International Airport (FWA)taxi taxi
    2. Fly from Fort Wayne International Airport (FWA) to Lambert–St. Louis International Airport (STL)plane plane FWA - STL
    5h 21m
    $252–830
  2. Drive 408.8 mi

    cheapest
    1. Drive from Defiance to St. Louiscar car 408.8 mi
    6h 57m
    $75–108
  3. Taxi, bus

    1. Take the taxi from Defiance to Van Werttaxi taxi
    2. Take the bus from Van Wert to Fort Wayne, INbus bus
    3. Take the bus from Fort Wayne, IN to Indianapolis, INbus bus
    4. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    9h 42m
    $149–277
  4. Train (Amtrak)

    1. Take the train from Bryan Amtrak Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    10h 5m
    $176–346
  5. Train, bus

    1. Take the train from Bryan Amtrak Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus N2521 / ...
    11h 38m
    $136–246

Fort Wayne International Airport (FWA) to Lambert–St. Louis International Airport (STL) flights

Calendar118Weekly Planes
Duration5h 15mAverage Duration
Ticket$102Cheapest Price
See schedules

Questions & Answers

What companies run services between Defiance, OH, USA and St. Louis, MO, USA?

You can take a vehicle from Defiance to St. Louis via Bryan Amtrak Station and Chicago Union Station in around 10h 5m.

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