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How to get fromDefiance to Buffaloby taxi, bus, train (Amtrak), car, train or plane

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There are 4 ways to get from Defiance to Buffalo by taxi, bus, train (Amtrak), car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus

    best
    1. Take the taxi from Defiance to Bowling Greentaxi
    2. Take the bus from Toledo Bus Stop to Cleveland Bus Stationbus
    3. Take the bus from Cleveland, OH to Buffalo, NYbus
    8h 28m
    $142–271

  2. Drive 347.9 mi

    cheapest
    1. Drive from Defiance to Buffalocar347.9 mi
    5h 57m
    $64–92

  3. Train (Amtrak)

    1. Take the train from Bryan Amtrak Station to Buffalo Depew StationtrainLake Shore Limited
    8h 59m
    $100–271

  4. Train, bus, fly

    1. Take the train from Bryan Amtrak Station to Toledotrain
    2. Take the bus from Toledo to Dearbornbus
    3. Fly from Detroit (DTW) to Buffalo Niagara International Airport (BUF)planeDTW - BUF
    8h 15m

Detroit (DTW) to Buffalo Niagara International Airport (BUF) flights

Calendar27Weekly Planes
Duration1h 16mAverage Duration
Ticket$129Cheapest Price
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Questions & Answers

What companies run services between Defiance, OH, USA and Buffalo, NY, USA?

Amtrak operates a train from Bryan Amtrak Station to Buffalo Depew Station twice daily. Tickets cost $35–130 and the journey takes 7h 8m.

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