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How to get fromDeWitt to Chicagoby bus, plane, train (Amtrak), car or train

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There are 7 ways to get from DeWitt to Chicago by bus, plane, train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Syracuse Hancock International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from E Genesee St & Terrace Dr to C22bus bus
    2. Fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD)plane plane SYR - ORD
    6h 9m
    $69–401

  2. Train (Amtrak)

    1. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train Lake Shore Limited
    13h 20m
    $191–389

  3. Drive 681 mi

    1. Drive from DeWitt to Chicagocar car 681 mi
    11h 37m
    $125–180

  4. Fly Syracuse Hancock International Airport to Chicago Midway International Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to Chicago Midway International Airport (MDW)plane plane SYR - MDW
    7h 32m
    $114–671

  5. Train to Rochester, fly to Chicago Midway International Airport

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane plane ROC - MDW
    6h 59m
    $142–779

  6. Train to Rochester, fly to Chicago O'Hare International Airport

    1. Take the train from Syracuse Regional Transportation Center to Rochestertrain train
    2. Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)plane plane ROC - ORD
    7h 19m
    $242–589

  7. Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Syracuse Bus Station to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    8h 4m
    $151–911

Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD) flights

Calendar75Weekly Planes
Duration3h 14mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

What companies run services between DeWitt, NY, USA and Chicago, IL, USA?

Amtrak operates a train from Syracuse Regional Transportation Center to Chicago Union Station twice daily. Tickets cost $150–340 and the journey takes 13h 7m. Alternatively, Delta, American Airlines, and Southwest Airlines fly from Syracuse Hancock International Airport (SYR) to Chicago Midway International Airport (MDW) 5 times a day.

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