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How to get fromDeWitt to Chicagoby bus, plane, train (Amtrak) or car

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There are 8 ways to get from DeWitt to Chicago by bus, plane, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Syracuse Hancock International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from E Genesee St & The Jewish Home to A1bus bus
    2. Fly from Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD)plane plane SYR - ORD
    6h 8m
    $79–481

  2. Train (Amtrak)

    1. Take the train from Syracuse Regional Transportation Center to Chicago Union Stationtrain train Lake Shore Limited
    13h 20m
    $121–279

  3. Drive 681 mi

    1. Drive from DeWitt to Chicagocar car 681 mi
    11h 37m
    $125–180

  4. Fly Syracuse Hancock International Airport to Chicago Midway International Airport

    1. Fly from Syracuse Hancock International Airport (SYR) to Chicago Midway International Airport (MDW)plane plane SYR - MDW
    7h 42m
    $114–721

  5. Bus to Rochester, fly to Chicago O'Hare International Airport

    1. Take the bus from Syracuse, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Chicago O'Hare International Airport (ORD)plane plane ROC - ORD
    6h 56m
    $133–543

  6. Bus to Rochester, fly to Chicago Midway International Airport

    1. Take the bus from Syracuse, NY to Rochester, NYbus bus
    2. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane plane ROC - MDW
    6h 56m
    $113–623

  7. Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Syracuse, NY to Buffalo, NYbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    7h 51m
    $103–568

  8. Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Syracuse, NY to Buffalo, NYbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    7h 45m
    $133–828

Syracuse Hancock International Airport (SYR) to Chicago O'Hare International Airport (ORD) flights

Calendar73Weekly Planes
Duration2h 59mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

What companies run services between DeWitt, NY, USA and Chicago, IL, USA?

Amtrak operates a train from Syracuse Regional Transportation Center to Chicago Union Station twice daily. Tickets cost $80–230 and the journey takes 13h 7m. Alternatively, Delta, American Airlines, and Southwest Airlines fly from Syracuse Hancock International Airport (SYR) to Chicago Midway International Airport (MDW) 3 times a day.

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