There are 4 ways to get from Cusco to Santiago by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  4h 3m

  1. Fly from Cuzco (CUZ) to Santiago (SCL) CUZ - SCL

$109 - $362

Cheapest option

Bus  •  46h 6m

  1. Take the bus from Cusco to Tacna
  2. Take the bus from Tacna to Arica
  3. Take the bus from Arica to Santiago - Terminal San Borja

$62 - $112

2 alternative options

Train, bus  •  47h 53m

  1. Take the train from Cusco - Wanchaq to Puno
  2. Take the bus from Puno to Tacna
  3. Take the bus from Tacna to Arica
  4. Take the bus from Arica to Santiago - Terminal San Borja

$332 - $382

Drive  •  36h 36m

  1. Drive from Cusco to Santiago 2894.5 km

$300 - $440

Questions & Answers

There is ongoing community transmission in Chile.
Last Updated: 3/11/2020 | Source: CDC.

Travel restrictions may apply and transportation services are subject to change. Please check before you travel.

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The cheapest way to get from Cusco to Santiago is to bus which costs $60 - $120 and takes 46h 6m.

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The quickest way to get from Cusco to Santiago is to fly which costs $100 - $370 and takes 4h 3m.

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No, there is no direct bus from Cusco to Santiago. However, there are services departing from Cusco and arriving at Santiago - Terminal San Borja via Tacna and Arica. The journey, including transfers, takes approximately 46h 6m.

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The distance between Cusco and Santiago is 2221 km. The road distance is 2894.5 km.

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The best way to get from Cusco to Santiago without a car is to bus which takes 46h 6m and costs $60 - $120.

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It takes approximately 4h 3m to get from Cusco to Santiago, including transfers.

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Cusco to Santiago bus services, operated by Cromotex, depart from Cusco station.

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The best way to get from Cusco to Santiago is to fly which takes 4h 3m and costs $100 - $370. Alternatively, you can bus, which costs $60 - $120 and takes 46h 6m.

Mode details

The quickest flight from Cuzco Airport to Santiago Airport is the direct flight which takes 3h 25m.

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Map of how to get from Cusco to Santiago.
Launch map view
  • Distance: 2220.6 km
  • Duration: 4h 3m

What companies run services between Cusco, Peru and Santiago, Chile?

LATAM Chile and Avianca - Aerovías del Continente Americano S.A. fly from Cusco to Santiago hourly. Alternatively, you can take a bus from Cusco to Santiago via Tacna and Arica in around 46h 6m.

Airlines
LATAM Chile
Website
latam.com
Flights from Cuzco to Santiago
Ave. Duration
3h 25m
When
Tuesday, Wednesday and Friday
Estimated price
$180 - $700
Flights from Cuzco to Santiago via Lima
Ave. Duration
6h 10m
When
Every day
Estimated price
$180 - $700
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Cuzco to Santiago via Lima
Ave. Duration
5h 55m
When
Every day
Estimated price
$240 - $1,100
Train operators
PeruRail
Phone
51-84-581414
Email
reservas@perurail.com
Website
perurail.com
Train from Cusco - Wanchaq to Puno
Ave. Duration
10h 28m
Frequency
4 times a week
Estimated price
$285
Schedules at
perurail.com
Book at
pax1.perurail.com
Bus operators
Cromotex
Phone
+51 (01) 424-75-75
Email
informes@cromotex.com.pe
Website
cromotex.com.pe
Bus from Cusco to Tacna
Ave. Duration
17h
Frequency
Once daily
Estimated price
$24
Schedules at
cromotex.com.pe
Book at
cromotex.com.pe
Buses Norte Grande
Phone
+56 58 222 8603
Email
reservas@busesng.cl
Website
busesng.cl
Bus from Tacna to Arica
Ave. Duration
1h
Frequency
Every 30 minutes
Estimated price
$3
Schedules at
busesng.cl
Chasquitur
Phone
+56 58 231967
Website
terminaldebuses.com
Bus from Tacna to Arica
Ave. Duration
1h
Frequency
Hourly
Estimated price
$3
Schedules at
terminaldebuses.com
Adsubliata
Phone
+56 58 262 495
Website
terminaldebuses.com
Bus from Tacna to Arica
Ave. Duration
1h
Frequency
Hourly
Estimated price
$3
Schedules at
terminaldebuses.com
Pullman Bus
Phone
+56 600 600 0018
Website
pullmanbus.com
Bus from Arica to Santiago - Terminal San Borja
Ave. Duration
27h
Frequency
4 times a day
Estimated price
$35 - $85
Schedules at
pullmanbus.com
Semi Cama
$35 - $55
Salón Cama
$55 - $85
Expreso Norte
Website
expresonorte.cl
Bus from Arica to Santiago
Ave. Duration
29h 40m
Frequency
4 times a day
Estimated price
$40 - $70
Website
Expreso Norte
Semi Cama
$40 - $55
Cama
$60 - $70
Fichtur VIP
Phone
+56 (02) 7205232
Bus from Arica to Santiago
Ave. Duration
28h 10m
Frequency
Once daily
Estimated price
$41
Schedules at
viajaenbus.cl

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More Questions & Answers

Cusco to Santiago bus services, operated by Pullman Bus, arrive at Santiago - Terminal San Borja station.

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Santiago is 2h ahead of Cusco. It is currently 3:48 PM in Cusco and 5:48 PM in Santiago.

Yes, the driving distance between Cusco to Santiago is 2894 km. It takes approximately 36h 36m to drive from Cusco to Santiago.

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Avianca - Aerovías del Continente Americano S.A. and LATAM Chile offer flights from Cuzco Airport to Santiago Airport.

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There are 1408+ hotels available in Santiago. Prices start at $100 USD per night.

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The best way to get from Cusco to Cuzco Airport is to taxi which takes 5 min and costs $6 - $8.

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