There are 8 ways to get from Cusco to Santa Maria by plane, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Santa Maria
best- Fly from Alejandro Velasco Astete International Airport (CUZ) to Santa Maria (RIA)CUZ - RIA
15h 55mR$1,997–6,234Fly to Salgado Filho International Airport, bus
cheapest- Fly from Alejandro Velasco Astete International Airport (CUZ) to Salgado Filho International Airport (POA)CUZ - POA
- Take the bus from Estação Rodoviária de Porto Alegre to Santa Cruz do Sul
- Take the bus from Santa Cruz do Sul to Estação Rodoviária de Santa Maria
14h 45mR$1,222–3,788Bus
- Take the bus from Cusco to Arequipa
- Take the bus from Arequipa to Tacna
- Take the bus from Tacna to Terminal de Ómnibus Córdoba T1
- Take the bus from Terminal de Ómnibus Córdoba T1 to Pantano Grande
- Take the bus from Terminal Rodoviário de Pântano Grande to Santa Cruz do Sul902
- Take the bus from Santa Cruz do Sul to Estação Rodoviária de Santa Maria151
3d 5hDrive 3,274.1 km
- Drive from Cusco to Santa Maria3,274.1 km
46h 34mR$2,635–3,806Fly to Passo Fundo, bus
- Fly from Alejandro Velasco Astete International Airport (CUZ) to Passo Fundo (PFB)CUZ - PFB
- Take the bus from Terminal Rodoviário de Passo Fundo to Terminal Rodoviário de Santa Maria - RS
16h 55mR$1,894–5,769Fly to Sepé Tiaraju Airport, bus
- Fly from Alejandro Velasco Astete International Airport (CUZ) to Sepé Tiaraju Airport (GEL)CUZ - GEL
- Take the bus from Rodoviária de Santo Ângelo to Estação Rodoviária de Santa Maria
18h 12mR$2,616–8,112Bus via Campo Grande
- Take the bus from Cusco to Campo Grande
- Take the bus from Campo Grande to Frederico Westphalen
- Take the bus from Terminal Rodoviário Frederico Westphalen to Terminal Rodoviário de Santa Maria - RS
3d 21hR$1,645–1,905Bus via Campo Grande #2
- Take the bus from Cusco to Campo Grande
- Take the bus from Terminal Rodoviário de Campo Grande to Rodoviária de Santo Ângelo
- Take the bus from Rodoviária de Santo Ângelo to Estação Rodoviária de Santa Maria
4dR$1,900–2,025
Alejandro Velasco Astete International Airport (CUZ) to Santa Maria (RIA) flights
Questions & Answers
The cheapest way to get from Cusco to Santa Maria is to bus via Campo Grande which costs R$ 1600 - R$ 2000 and takes 3 days 21h.
The fastest way to get from Cusco to Santa Maria is to fly and bus which takes 14h 45m and costs R$ 1200 - R$ 3800.
No, there is no direct bus from Cusco to Santa Maria. However, there are services departing from Cusco and arriving at Estação Rodoviária de Santa Maria via Arequipa, Tacna, Terminal de Ómnibus Córdoba T1, Terminal Rodoviário de Pântano Grande and Santa Cruz do Sul. The journey, including transfers, takes approximately 3 days 5h.
The distance between Cusco and Santa Maria is 2611 km. The road distance is 3274.1 km.
The best way to get from Cusco to Santa Maria without a car is to bus which takes 3 days 5h and costs .
It takes approximately 15h 55m to get from Cusco to Santa Maria, including transfers.
Cusco to Santa Maria bus services, operated by Andoriña Tours, depart from Cusco station.
The best way to get from Cusco to Santa Maria is to fly which takes 15h 55m and costs R$ 2000 - R$ 6500. Alternatively, you can bus, which costs and takes 3 days 5h.
Cusco to Santa Maria bus services, operated by Andoriña Tours, arrive at Arequipa station.
Santa Maria is 2h ahead of Cusco. It is currently 6:17 PM in Cusco and 8:17 PM in Santa Maria.
What companies run services between Cusco, Peru and Santa Maria, Rio Grande do Sul, Brazil?
LATAM Chile, Azul, and JetSMART fly from Alejandro Velasco Astete International Airport (CUZ) to Santa Maria (RIA) once daily. Alternatively, you can take a bus from Cusco to Estação Rodoviária de Santa Maria via Arequipa, Tacna, Terminal de Ómnibus Córdoba T1, Pantano Grande, Terminal Rodoviário de Pântano Grande, and Santa Cruz do Sul in around 3d 5h.
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- Website
- voeazul.com.br
Flights from Alejandro Velasco Astete International Airport to Santa Maria via Lima, Salgado Filho International Airport
- Ave. Duration
- 15h 44m
- When
- Wednesday and Friday
- Estimated price
- R$1,900–6,500
Flights from Alejandro Velasco Astete International Airport to Santa Maria via Arequipa, Lima, Salgado Filho International Airport
- Ave. Duration
- 18h 45m
- When
- Wednesday and Friday
- Estimated price
- R$2,100–7,000
Flights from Alejandro Velasco Astete International Airport to Santa Maria via Puerto Maldonado, Lima, Salgado Filho International Airport
- Ave. Duration
- 22h 10m
- When
- Wednesday and Friday
- Estimated price
- R$2,100–7,000
Flights from Alejandro Velasco Astete International Airport to Sepé Tiaraju Airport via Lima, Salgado Filho International Airport
- Ave. Duration
- 12h 54m
- When
- Sunday
- Estimated price
- R$2,500–8,000
Flights from Alejandro Velasco Astete International Airport to Sepé Tiaraju Airport via Arequipa, Lima, Salgado Filho International Airport
- Ave. Duration
- 15h 55m
- When
- Sunday
- Estimated price
- R$2,700–8,500
Flights from Alejandro Velasco Astete International Airport to Sepé Tiaraju Airport via Puerto Maldonado, Lima, Salgado Filho International Airport
- Ave. Duration
- 19h 20m
- When
- Sunday
- Estimated price
- R$2,700–9,000
- Website
- latam.com
Flights from Alejandro Velasco Astete International Airport to Passo Fundo via Lima, Sao Paulo
- Ave. Duration
- 17h 6m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- R$1,700–5,500
Flights from Alejandro Velasco Astete International Airport to Salgado Filho International Airport via Lima
- Ave. Duration
- 7h 29m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- R$1,100–3,600
Flights from Alejandro Velasco Astete International Airport to Salgado Filho International Airport via Arequipa, Lima
- Ave. Duration
- 10h 30m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- R$1,200–3,900
Flights from Alejandro Velasco Astete International Airport to Salgado Filho International Airport via Puerto Maldonado, Lima
- Ave. Duration
- 13h 55m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- R$1,200–3,900
Flights from Alejandro Velasco Astete International Airport to Salgado Filho International Airport via Lima, Florianopolis
- Ave. Duration
- 14h 40m
- When
- Friday
- Estimated price
- R$1,200–3,800
- Website
- avianca.com
Flights from Alejandro Velasco Astete International Airport to Passo Fundo via Bogota, Sao Paulo
- Ave. Duration
- 20h 10m
- When
- Wednesday and Friday
- Estimated price
- R$2,100–7,000
Flights from Alejandro Velasco Astete International Airport to Passo Fundo via Lima, Sao Paulo
- Ave. Duration
- 10h 21m
- When
- Monday, Wednesday, and Friday
- Estimated price
- R$1,700–5,500
Flights from Alejandro Velasco Astete International Airport to Passo Fundo via Santiago, Sao Paulo
- Ave. Duration
- 17h 55m
- When
- Wednesday and Friday
- Estimated price
- R$1,900–6,000
Flights from Alejandro Velasco Astete International Airport to Passo Fundo via Arequipa, Lima, Sao Paulo
- Ave. Duration
- 14h 35m
- When
- Monday, Wednesday, and Friday
- Estimated price
- R$1,800–6,000
- Website
- voegol.com.br
Flights from Alejandro Velasco Astete International Airport to Passo Fundo via Lima, Sao Paulo
- Ave. Duration
- 10h 21m
- When
- Monday, Wednesday, and Friday
- Estimated price
- R$1,700–5,500
Flights from Alejandro Velasco Astete International Airport to Passo Fundo via Santiago, Sao Paulo
- Ave. Duration
- 17h 55m
- When
- Wednesday and Friday
- Estimated price
- R$1,900–6,000
Flights from Alejandro Velasco Astete International Airport to Passo Fundo via Arequipa, Lima, Sao Paulo
- Ave. Duration
- 14h 35m
- When
- Monday, Wednesday, and Friday
- Estimated price
- R$1,800–6,000
Flights from Alejandro Velasco Astete International Airport to Sepé Tiaraju Airport via Lima, Sao Paulo
- Ave. Duration
- 19h 15m
- When
- Tuesday and Sunday
- Estimated price
- R$2,800–9,000
- Phone
- +51 993 585 217
Bus from Cusco to Arequipa
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Schedules at
- facebook.com
- Book at
- redbus.pe
- Phone
- +51 953 954 708
- informes@transportesmoquegua.com.pe
- Website
- redbus.pe
Bus from Arequipa to Tacna
- Ave. Duration
- 2h 15m
- Frequency
- Every 3 hours
- Estimated price
- R$96
- Schedules at
- redbus.pe
- Phone
- 0800 444 8356
- consultas@gestionbus.com.ar
- Website
- lavelozdelnorte.com.ar
Bus from Tacna to Terminal de Ómnibus Córdoba T1
- Ave. Duration
- 41h 45m
- Frequency
- Twice a week
- Estimated price
- R$430–750
- Schedules at
- lavelozdelnorte.com.ar
- Book at
- lavelozdelnorte.com.ar
- Semicama
- R$430–650
- Cama
- R$500–750
- Phone
- 0810 222-5202
- atencionalcliente@flechabus.com.ar
- Website
- flechabus.com.ar
Bus from Terminal de Ómnibus Córdoba T1 to Pantano Grande
- Ave. Duration
- 20h 22m
- Frequency
- Once a week
- Estimated price
- R$420–700
- Website
- https://www.flechabus.com.ar/home?lang=en_US
- Semi Cama
- R$420–550
- Cama
- R$470–700
- Phone
- 0800 940 5515
- atendimento@santacruzbus.com.br
- Website
- santacruzbus.com.br
Bus from Terminal Rodoviário de Pântano Grande to Santa Cruz do Sul
- Ave. Duration
- 42 min
- Frequency
- Every 3 hours
- Estimated price
- R$28–85
- Schedules at
- santacruzbus.com.br
- Book at
- santacruzbus.com.br
- Convencional
- R$28–40
- Executivo
- R$35–50
- Semi-Leito
- R$75–85
Bus from Santa Cruz do Sul to Estação Rodoviária de Santa Maria
- Ave. Duration
- 2h 25m
- Frequency
- Hourly
- Estimated price
- R$45–115
- Schedules at
- santacruzbus.com.br
- Book at
- santacruzbus.com.br
- Convencional
- R$45–70
- Executivo
- R$60–75
- Semi-Leito
- R$100–115
Bus from Estação Rodoviária de Porto Alegre to Santa Cruz do Sul
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- R$50–120
- Schedules at
- santacruzbus.com.br
- Book at
- santacruzbus.com.br
- Convencional
- R$50–75
- Executivo
- R$65–85
- Semi-Leito
- R$105–120
- Phone
- +55 55 4020-7488
- sac@planalto.com.br
- Website
- planalto.com.br
Bus from Terminal Rodoviário de Passo Fundo to Terminal Rodoviário de Santa Maria - RS
- Ave. Duration
- 5h 37m
- Frequency
- Twice daily
- Estimated price
- R$150–380
- Schedules at
- planalto.com.br
- Book at
- planalto.com.br
Bus from Terminal Rodoviário Frederico Westphalen to Terminal Rodoviário de Santa Maria - RS
- Ave. Duration
- 5h 56m
- Frequency
- Twice daily
- Estimated price
- R$160–390
- Schedules at
- planalto.com.br
- Book at
- planalto.com.br
- Phone
- 08005 518666
- sac@ouroeprata.com
- Website
- viacaoouroeprata.com.br
Bus from Rodoviária de Santo Ângelo to Estação Rodoviária de Santa Maria
- Ave. Duration
- 4h 9m
- Frequency
- 3 times a day
- Estimated price
- R$75–144
- Schedules at
- viacaoouroeprata.com.br
- Book at
- viacaoouroeprata.com.br
- Semi-Direto
- R$75–110
Bus from Terminal Rodoviário de Campo Grande to Rodoviária de Santo Ângelo
- Ave. Duration
- 25h 13m
- Frequency
- Once daily
- Estimated price
- R$550–600
- Schedules at
- viacaoouroeprata.com.br
- Book at
- viacaoouroeprata.com.br
- Phone
- +55 (68) 3221-1660
- Website
- transacreana.com.br
Bus from Cusco to Campo Grande
- Ave. Duration
- 2d 17h
- Frequency
- Once a week
- Estimated price
- R$1,276
- Schedules at
- transacreana.com.br
- Book at
- transacreana.com.br
- Phone
- +55 (54) 3363.1035
- sac@valturturismo.com.br
- Website
- valturturismo.com.br
Bus from Campo Grande to Frederico Westphalen
- Ave. Duration
- 20h 38m
- Frequency
- 3 times a week
- Estimated price
- R$210–240
- Schedules at
- valturturismo.com.br
- Book at
- valturturismo.com.br
- Convencional
- R$210–240
- Executivo
- R$210–240
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More Questions & Answers
Yes, the driving distance between Cusco to Santa Maria is 3274 km. It takes approximately 46h 34m to drive from Cusco to Santa Maria.
There are 79+ hotels available in Santa Maria.

























