There are 5 ways to get from Cusco to Guayaquil by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  4 h 49 min

  1. Fly from Cuzco (CUZ) to Guayaquil (GYE) CUZ - GYE

$202 - $677

Cheapest option

Bus Cruz del Sur  •  2 days 2 h

  1. Take the bus from Cusco to Lima Javier Prado
  2. Take the bus from Lima Javier Prado to Guayaquil Via Guayaquil / ...

$140 - $260

3 alternative options

Bus Linea de Los Andes  •  37 h 43 min

  1. Take the bus from Cusco to Lima
  2. Take the bus from Lima to Guayaquil Via Guayaquil / ...

$145 - $272

Bus Expreso Internacional Ormeño  •  2 days 16 h

  1. Take the bus from Cusco to Puerto Maldonado
  2. Take the bus from Puerto Maldonado to Guayaquil Via Bogota

$153 - $445

Drive  •  37 h 44 min

  1. Drive from Cusco to Guayaquil 1639.1 miles

$230 - $350

Questions & Answers

The cheapest way to get from Cusco to Guayaquil is to bus which costs $140 - $280 and takes 37 h 43 min.

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The quickest way to get from Cusco to Guayaquil is to fly which costs $200 - $700 and takes 4 h 49 min.

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The distance between Cusco and Guayaquil is 1532 km. The road distance is 2622.5 km.

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The best way to get from Cusco to Guayaquil without a car is to bus which takes 37 h 43 min and costs $140 - $280.

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It takes approximately 4 h 49 min to get from Cusco to Guayaquil, including transfers.

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The best way to get from Cusco to Guayaquil is to fly which takes 4 h 49 min and costs $200 - $700. Alternatively, you can bus, which costs $140 - $280 and takes 37 h 43 min.

Mode details

There is no direct flight from Cuzco Airport to Guayaquil Airport. The quickest flight takes 4 h 33 min and has one stopover.

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Yes, the driving distance between Cusco to Guayaquil is 2623 km. It takes approximately 37 h 44 min to drive from Cusco to Guayaquil.

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Avianca - Aerovías del Continente Americano S.A. and LATAM Chile offer flights from Cuzco Airport to Guayaquil Airport.

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There are 291+ hotels available in Guayaquil. Prices start at $25 USD per night.

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The best way to get from Cusco to Cuzco Airport is to taxi which takes 5 min and costs $2 - $4.

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Map of how to get from Cusco to Guayaquil.
Launch map view
  • Distance: 957.3 miles
  • Duration: 4 h 49 min

What companies run services between Cusco, Peru and Guayaquil, Ecuador?

LATAM Chile, Avianca - Aerovías del Continente Americano S.A. and three other airlines fly from Cusco to Guayaquil hourly. Alternatively, you can take a bus from Cusco to Guayaquil via Lima and Guayaquil in around 37 h 43 min.

Airlines
LATAM Chile
Website
latam.com
Flights from Cuzco to Guayaquil via Lima
Ave. Duration
4 h 34 min
When
Every day
Estimated price
$380 - $1,000
Flights from Cuzco to Guayaquil via Juliaca, Lima
Ave. Duration
7 h 47 min
When
Tuesday, Wednesday, Thursday and Saturday
Estimated price
$380 - $1,000
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Cuzco to Guayaquil via Lima
Ave. Duration
5 h 6 min
When
Every day
Estimated price
$240 - $700
Flights from Cuzco to Guayaquil via Bogota
Ave. Duration
8 h 32 min
When
Every day
Estimated price
$240 - $700
Flights from Cuzco to Guayaquil via Lima, Quito
Ave. Duration
9 h 41 min
When
Every day
Estimated price
$240 - $700
Bus operators
Tepsa
Website
tepsa.com.pe
Bus from Cusco to Lima Plaza Norte
Ave. Duration
22 h 35 min
Frequency
Twice daily
Estimated price
$30 - $50
Schedules at
tepsa.com.pe
Suite
$40 - $50
Regular
$30 - $50
Bus from Cusco to Puerto Maldonado
Ave. Duration
10 h
Frequency
Once daily
Estimated price
$15 - $50
Schedules at
tepsa.com.pe
Suite
$40 - $50
Regular
$26 - $40
Cruz del Sur
Phone
+51 1 311-5050
Website
cruzdelsur.com.pe
Bus from Lima to Guayaquil
Ave. Duration
24 h
Frequency
Once a week
Estimated price
$100 - $170
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe
Bus from Cusco to Lima Javier Prado
Ave. Duration
21 h 30 min
Frequency
Twice daily
Estimated price
$24 - $65
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe
Regular in Advance
$24 - $35
Regular
$35 - $55
VIP
$45 - $65
Bus from Lima Javier Prado to Guayaquil
Ave. Duration
27 h 30 min
Frequency
6 times a week
Estimated price
$95 - $170
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe
Movil Tours
Phone
716-8000
Email
info@moviltours.com.pe
Website
moviltours.com.pe
Bus from Cusco to Puerto Maldonado
Ave. Duration
11 h
Frequency
3 times a day
Estimated price
$15 - $70
Schedules at
moviltours.com.pe
Economy
$27 - $40
Regular
$35 - $50
Suite
$50 - $70
CIVA
Website
civa.com.pe
Bus from Cusco to Puerto Maldonado
Ave. Duration
10 h
Frequency
Twice daily
Estimated price
$12 - $50
Schedules at
civa.com.pe
Regular Semi Bed
$21 - $29
Regular Bed
$26 - $40
Economy
$13 - $18
Premium Semi Bed
$29 - $40
Premium Bed
$35 - $50
Transzela

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