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There are 5 ways to get from Cusco to Guayaquil by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  5h 1m

  1. Fly from Cuzco (CUZ) to Guayaquil (GYE) CUZ - GYE

$202 - $677

Cheapest option

Bus Skybus  •  45h 42m

  1. Take the bus from Cusco to Lima Via Lima
  2. Take the bus from Lima to Guayaquil Via Cucuta / ...

$123 - $252

3 alternative options

Bus Cruz del Sur  •  2 days 1h

  1. Take the bus from Cusco to Lima Javier Prado Cusco
  2. Take the bus from Lima Javier Prado to Guayaquil Via Guayaquil / ...

$146 - $259

Bus Expreso Internacional Ormeño  •  2 days 15h

  1. Take the bus from Cusco to Puerto Maldonado Via Puerto Maldonado / ...
  2. Take the bus from Puerto Maldonado to Guayaquil Via Bogota

$153 - $406

Drive  •  37h 44m

  1. Drive from Cusco to Guayaquil 1639.1 miles

$230 - $350

Questions & Answers

The cheapest way to get from Cusco to Guayaquil is to bus which costs $120 - $260 and takes 45h 42m.

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The quickest way to get from Cusco to Guayaquil is to fly which costs $200 - $700 and takes 5h 1m.

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The distance between Cusco and Guayaquil is 1532 km. The road distance is 2622.5 km.

Get driving directions

The best way to get from Cusco to Guayaquil without a car is to bus which takes 45h 42m and costs $120 - $260.

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It takes approximately 5h 1m to get from Cusco to Guayaquil, including transfers.

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The best way to get from Cusco to Guayaquil is to fly which takes 5h 1m and costs $200 - $700. Alternatively, you can bus, which costs $120 - $260 and takes 45h 42m.

Mode details

There is no direct flight from Cuzco Airport to Guayaquil Airport. The quickest flight takes 4h 45m and has one stopover.

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Yes, the driving distance between Cusco to Guayaquil is 2623 km. It takes approximately 37h 44m to drive from Cusco to Guayaquil.

Get driving directions

LATAM Chile and Avianca - Aerovías del Continente Americano S.A. offer flights from Cuzco Airport to Guayaquil Airport.

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There are 300+ hotels available in Guayaquil. Prices start at $25 USD per night.

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Map of how to get from Cusco to Guayaquil.
Launch map view
  • Distance: 957.3 miles
  • Duration: 5h 1m

What companies run services between Cusco, Peru and Guayaquil, Ecuador?

LATAM Chile, Avianca - Aerovías del Continente Americano S.A. and four other airlines fly from Cusco to Guayaquil hourly. Alternatively, you can take a bus from Cusco to Guayaquil via Lima and Guayaquil in around 45h 42m.

Airlines
LATAM Chile
Website
latam.com
Flights from Cuzco to Guayaquil via Lima
Ave. Duration
4h 46m
When
Every day
Estimated price
$380 - $1,000
Flights from Cuzco to Guayaquil via Arequipa, Lima
Ave. Duration
8h 3m
When
Monday, Wednesday, Friday and Sunday
Estimated price
$380 - $1,000
Flights from Cuzco to Guayaquil via Juliaca, Lima
Ave. Duration
8h 9m
When
Tuesday, Thursday and Saturday
Estimated price
$380 - $1,000
Avianca - Aerovías del Continente Americano S.A.
Website
avianca.com
Flights from Cuzco to Guayaquil via Lima
Ave. Duration
5h 5m
When
Every day
Estimated price
$240 - $700
Flights from Cuzco to Guayaquil via Bogota
Ave. Duration
7h 15m
When
Every day
Estimated price
$240 - $700
Flights from Cuzco to Guayaquil via Lima, Bogota
Ave. Duration
9h
When
Every day
Estimated price
$240 - $700
Flights from Cuzco to Guayaquil via Lima, Quito
Ave. Duration
9h 40m
When
Every day
Estimated price
$240 - $700
Bus operators
Expreso Los Chankas
Skybus
Phone
+58 414 8448807
Website
facebook.com
Bus from Lima to Guayaquil
Ave. Duration
25h 30m
Frequency
4 times a day
Schedules at
facebook.com
Cruz del Sur
Phone
+51 1 311-5050
Website
cruzdelsur.com.pe
Bus from Lima to Guayaquil
Ave. Duration
24h
Frequency
Once a week
Estimated price
$100 - $170
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe
Bus from Cusco to Lima Javier Prado
Ave. Duration
20h 30m
Frequency
Twice daily
Estimated price
$24 - $65
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe
Regular in Advance
$24 - $35
Regular
$35 - $50
VIP
$45 - $65
Bus from Lima Javier Prado to Guayaquil
Ave. Duration
27h 30m
Frequency
Once daily
Estimated price
$100 - $170
Schedules at
cruzdelsur.com.pe
Book at
cruzdelsur.com.pe
CIVA
Phone
+51 (1) 418-1111
Email
callcenter@turismociva.com
Website
civa.com.pe
Bus from Cusco to Puerto Maldonado
Ave. Duration
10h
Frequency
4 times a day
Estimated price
$12 - $23
Schedules at
civa.com.pe
Book at
civa.com.pe
Economy
$13 - $18
Semi Bed
$17 - $23
Bed Regular
$26 - $35
Bed Premium
$27 - $33
Suite
$29 - $40
Movil Tours
Phone
+51 1 716-8000
Email
info@moviltours.com.pe
Website
moviltours.com.pe
Bus from Cusco to Puerto Maldonado
Ave. Duration
11h
Frequency
3 times a day
Estimated price
$15 - $40
Schedules at
moviltours.com.pe
Economy
$20 - $25
Semi bed
$21 - $30
Bed
$28 - $40
Tepsa
Phone
+51 1 6179000
Website
tepsa.com.pe
Bus from Cusco to Puerto Maldonado
Ave. Duration
10h
Frequency
Once daily
Estimated price
$15 - $45
Schedules at
tepsa.com.pe
Bed
$30 - $45
Semi Bed
$26 - $31
Transzela

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More Questions & Answers

The best way to get from Cusco to Cuzco Airport is to taxi which takes 5m and costs $2 - $4.

More details