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How to get fromComiso to Sienaby plane, train, bus, train (Trenitalia), car, or car ferry

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There are 9 ways to get from Comiso to Siena by plane, train, bus, train (Trenitalia), car, or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Pisa International Airport, train

    best
    1. Fly from Vincenzo Magliocco Airport (CIY) to Pisa International Airport (PSA)plane plane CIY - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    4h 1m
    €100–275

  2. Bus

    cheapest
    1. Take the bus from Licata Piazzale Martiri Delle Foibe to Florence Villa Constanza Bus Stationbus bus Autoservizi Salemi 700
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    20h 54m
    €60–86

  3. Bus via Catania Airport (CTA)

    1. Take the bus from Ragusa Bus Terminal to Aeroporto Vincenzo Bellini/Fontanarossabus bus Ragusa
    2. Take the bus from Catania Airport to Sienabus bus N597 / ...
    18h
    €66–142

  4. Train via Rome (Trenitalia)

    1. Take the train from Comiso to Siracusatrain train Re
    2. Take the train from Siracusa to Roma Terminitrain train Ic
    3. Take the train from Roma Termini to Firenze S.M.N.train train Fr
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    18h 24m
    €140–312

  5. Drive, car ferry

    1. Drive from Comiso to Tresmestiericar car
    2. Take the car ferry from Tresmestieri to Villa S. Giovannicarferry car ferry
    3. Drive from Villa S. Giovanni to Sienacar car
    11h 10m
    €188–287

  6. Fly to Florence Peretola Airport, train

    1. Fly from Vincenzo Magliocco Airport (CIY) to Florence Peretola Airport (FLR)plane plane CIY - FLR
    2. Take the train from Firenze Rifredi to Sienatrain train
    5h 40m
    €95–285

  7. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Vincenzo Magliocco Airport (CIY) to Bologna Guglielmo Marconi Airport (BLQ)plane plane CIY - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    4h 31m
    €108–304

  8. Fly to Fiumicino International Airport, train

    1. Fly from Vincenzo Magliocco Airport (CIY) to Fiumicino International Airport (FCO)plane plane CIY - FCO
    2. Take the train from Roma Termini to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    5h 31m
    €89–236

  9. Train (Trenitalia)

    1. Take the train from Comiso to Siracusatrain train Re
    2. Take the train from Siracusa to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    22h 7m
    €158–267

Comiso to Siena by bus

Calendar22Weekly Buses
Duration18hAverage Duration
Ticket€66Cheapest Price
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Questions & Answers

Map of how to get from Comiso to Siena.ExpandLaunch map view
  • Distance: 943.9 km
  • Duration: 4h 1m

What companies run services between Comiso, Italy and Siena, Italy?

You can take a bus from Comiso to Siena via Ragusa Bus Terminal, Aeroporto Vincenzo Bellini/Fontanarossa, and Catania Airport in around 18h. Alternatively, you can take a train from Comiso to Siena via Siracusa, Roma Termini, and Firenze S.M.N. in around 18h 24m.

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