There are 11 ways to get from Comiso to Siena by plane, train, bus, train (Trenitalia), night train, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Vincenzo Magliocco Airport to Bologna Guglielmo Marconi Airport, train
best- Fly from Vincenzo Magliocco Airport (CIY) to Bologna Guglielmo Marconi Airport (BLQ)plane CIY - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
4h 41m€108–403Bus to Catania–Fontanarossa Airport, fly to Bologna Guglielmo Marconi Airport, train
cheapest- Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stopbus
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)plane CTA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 37m€48–232Bus via Catania Airport (CTA)
- Take the bus from Ragusa Bus Terminal to Aeroporto Vincenzo Bellini/Fontanarossabus Ragusa
- Take the bus from Catania Airport to Sienabus N597 / ...
18h€54–142Train (Trenitalia)
- Take the train from Comiso to Siracusatrain Re
- Take the train from Siracusa to Roma Terminitrain Ic
- Take the train from Roma Termini to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
18h 33m€140–264Train, night train
- Take the train from Comiso to Siracusatrain Re
- Take the nighttrain from Siracusa to Firenze Campo Martenighttrain Ini
- Take the train from Firenze S.M.N. to Sienatrain Re
21h 56m€124–200Fly Vincenzo Magliocco Airport to Fiumicino International Airport, train
- Fly from Vincenzo Magliocco Airport (CIY) to Fiumicino International Airport (FCO)plane CIY - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
5h 40m€89–372Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
- Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stopbus
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane CTA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 57m€49–212Fly Vincenzo Magliocco Airport to Florence Peretola Airport, train
- Fly from Vincenzo Magliocco Airport (CIY) to Florence Peretola Airport (FLR)plane CIY - FLR
- Take the train from Firenze S.M.N. to Sienatrain
5h 56m€136–473Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train
- Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stopbus
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane CTA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 54m€62–240Bus
- Take the bus from Gela Bus Station to Florence Villa Constanza Bus Stationbus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
21h 20m€191–264Drive, car ferry
- Drive from Comiso to Tresmestiericar
- Take the carferry from Tresmestieri to Villa S. Giovannicarferry
- Drive from Villa S. Giovanni to Sienacar
11h 10m€188–287
Comiso to Siena by bus
Comparing Your Travel Options
The cheapest way to get from Comiso to Siena is to bus via Catania Airport (CTA) which costs €50 - €150 and takes 18h.
The fastest way to get from Comiso to Siena is to fly and train which takes 4h 41m and costs €100 - €410.
No, there is no direct bus from Comiso to Siena. However, there are services departing from Comiso and arriving at Siena via Ragusa Bus Terminal and Catania Airport. The journey, including transfers, takes approximately 18h.
No, there is no direct train from Comiso to Siena. However, there are services departing from Comiso and arriving at Siena via Siracusa, Roma Termini and Firenze S.M.N.. The journey, including transfers, takes approximately 18h 33m.
The distance between Comiso and Siena is 1079 km.
The best way to get from Comiso to Siena without a car is to bus via Catania Airport (CTA) which takes 18h and costs €50 - €150.
It takes approximately 4h 41m to get from Comiso to Siena, including transfers.
Comiso to Siena bus services, operated by Interbus, depart from Ragusa Bus Terminal station.
Comiso to Siena train services, operated by Trenitalia, depart from Comiso station.
The best way to get from Comiso to Siena is to bus via Catania Airport (CTA) which takes 18h and costs €50 - €150. Alternatively, you can train, which costs €140 - €270 and takes 18h 33m.
What companies run services between Comiso, Italy and Siena, Italy?
You can take a bus from Comiso to Siena via Ragusa Bus Terminal, Aeroporto Vincenzo Bellini/Fontanarossa, and Catania Airport in around 18h. Alternatively, you can take a train from Comiso to Siena via Siracusa, Roma Termini, and Firenze S.M.N. in around 18h 33m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €30–190
Flights from Catania–Fontanarossa Airport to Pisa International Airport via Bari
- Ave. Duration
- 3h 25m
- When
- Tuesday
- Estimated price
- €30–190
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €40–220
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Bari
- Ave. Duration
- 3h 45m
- When
- Wednesday
- Estimated price
- €40–220
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Malta
- Ave. Duration
- 4h 15m
- When
- Monday
- Estimated price
- €40–220
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 37m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Ragusa Bus Terminal to Aeroporto Vincenzo Bellini/Fontanarossa
- Ave. Duration
- 1h 45m
- Frequency
- Every 3 hours
- Estimated price
- €4–12
- Schedules at
- interbus.it
- Phone
- 090774409
- info@bluferries.it
- Website
- bluferries.it
Car ferry from Tresmestieri to Villa S. Giovanni
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Comiso to Siena bus services, operated by Interbus, arrive at Aeroporto Vincenzo Bellini/Fontanarossa station.
Comiso to Siena train services, operated by Trenitalia, arrive at Siracusa station.
Book your Comiso to Siena train tickets online with Omio.
Book your Comiso to Siena bus tickets online with Omio.
There are 2465+ hotels available in Siena.











