There are 9 ways to get from Comiso to Siena by plane, train, bus, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Vincenzo Magliocco Airport to Fiumicino International Airport, train
best- Fly from Vincenzo Magliocco Airport (CIY) to Fiumicino International Airport (FCO)CIY - FCO
- Take the train from Roma Termini to Florence Santa Maria Novella
- Take the train from Firenze S.M.N. to Siena
6h 29m€80–385Bus via Rome
cheapest- Take the bus from Gela Bus Station to Roma, Autostazione TiburtinaAutoservizi Salemi 701
- Take the bus from Roma, Autostazione Tiburtina to Siena - p.zza RosselliLamezia Terme
18h 15m€37–53Bus
- Take the bus from Ragusa Via Scalo Merci to Catania Fontanarossa Airport Bus StopEtna Trasporti ET01
- Take the bus from Catania Airport to SienaN597 / ...
17h 33m€65–101Train, bus
- Take the train from Comiso to SiracusaRe
- Take the train from Siracusa to Firenze S.M.N.
- Take the bus from Firenze Autostazione to Siena-Via Tozzi131
20h 8mDrive, ferry
- Drive from Comiso to Messina Marittima
- Take the ferry from Messina Marittima to Villa San Giovanni
- Drive from Villa San Giovanni to Siena
11h 2m€171–256Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
- Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stop
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)CTA - FLR
- Take the train from Firenze S.M.N. to Siena
8h 15m€53–225Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train
- Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stop
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)CTA - PSA
- Take the train from Pisa Centrale to Empoli
- Take the train from Empoli to Siena
8h 5m€74–231Fly Vincenzo Magliocco Airport to Florence Peretola Airport, train
- Fly from Vincenzo Magliocco Airport (CIY) to Florence Peretola Airport (FLR)CIY - FLR
- Take the train from Firenze S.M.N. to Siena
6h 44m€118–392Bus to Catania–Fontanarossa Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stop
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)CTA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Siena
9h€59–312
Comiso to Siena by bus
Questions & Answers
The cheapest way to get from Comiso to Siena is to bus via Rome which costs €35 - €55 and takes 18h 15m.
The fastest way to get from Comiso to Siena is to fly and train which takes 6h 29m and costs €80 - €390.
No, there is no direct bus from Comiso to Siena. However, there are services departing from Comiso and arriving at Siena via Ragusa Via Scalo Merci and Catania Airport. The journey, including transfers, takes approximately 17h 33m.
The distance between Comiso and Siena is 962 km.
The best way to get from Comiso to Siena without a car is to bus which takes 17h 33m and costs €65 - €110.
It takes approximately 6h 29m to get from Comiso to Siena, including transfers.
Comiso to Siena bus services, operated by Etna Trasporti, depart from Ragusa Via Scalo Merci station.
Comiso to Siena bus services, operated by Etna Trasporti, arrive at Catania Fontanarossa Airport Bus Stop station.
Book your Comiso to Siena bus tickets online with FlixBus.
There are 2196+ hotels available in Siena.
What companies run services between Comiso, Italy and Siena, Italy?
You can take a bus from Comiso to Siena via Ragusa Via Scalo Merci, Catania Fontanarossa Airport Bus Stop, and Catania Airport in around 17h 33m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €45–180
Flights from Catania–Fontanarossa Airport to Pisa International Airport via Malta
- Ave. Duration
- 3h 45m
- When
- Friday
- Estimated price
- €45–180
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €40–210
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €70–160
Flights from Vincenzo Magliocco Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- €100–360
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Fiumicino International Airport
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €50–160
- Website
- aeroitalia.com
Flights from Vincenzo Magliocco Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €30–440
- Website
- flexflight.dk
Flights from Vincenzo Magliocco Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €30–440
- Website
- flyulendo.com
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €23–190
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €27–170
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €30–200
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Florence Santa Maria Novella
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €22–60
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €15–40
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €6–18
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €12–18
Train from Comiso to Siracusa
- Ave. Duration
- 2h 46m
- Frequency
- 3 times a day
- Estimated price
- €9–26
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €18–26
Train from Siracusa to Firenze S.M.N.
- Ave. Duration
- 14h 45m
- Frequency
- 3 times a week
- Estimated price
- €55–200
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €140–200
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–9
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €6–9
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €5–12
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €8–12
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- €6–17
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €12–17
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–13
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 06 164160
- info@etnatrasporti.it
- Website
- etnatrasporti.it
Bus from Ragusa Via Scalo Merci to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
Bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Ragusa Via Scalo Merci to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- €10–15
- Website
- https://www.flixbus.co.uk
Bus from Catania Airport to Siena
- Ave. Duration
- 13h 45m
- Frequency
- Twice daily
- Estimated price
- €55–80
- Website
- https://www.flixbus.co.uk
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Gela Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 12h 15m
- Frequency
- Once a week
- Estimated price
- €27–40
- Schedules at
- autoservizisalemi.it
Bus from Roma, Autostazione Tiburtina to Siena - p.zza Rosselli
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- €10–15
- Schedules at
- autolineefederico.it
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
Want to know more about travelling around Italy
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