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How to get fromComiso to Sienaby plane, train, bus, train (Trenitalia), car or ferry

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There are 10 ways to get from Comiso to Siena by plane, train, bus, train (Trenitalia), car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Vincenzo Magliocco Airport to Fiumicino International Airport, train

    best
    1. Fly from Vincenzo Magliocco Airport (CIY) to Fiumicino International Airport (FCO)plane plane CIY - FCO
    2. Take the train from Roma Termini to Florence Santa Maria Novellatrain train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    6h 23m
    €82–268
  2. Bus via Catania Airport (CTA)

    cheapest
    1. Take the bus from Ragusa Bus Terminal to Aeroporto Vincenzo Bellini/Fontanarossabus bus Ragusa
    2. Take the bus from Catania Airport to Sienabus bus N597 / ...
    18h
    €36–89
  3. Train

    1. Take the train from Comiso to Siracusatrain train Re
    2. Take the train from Siracusa to Roma Terminitrain train Ic
    3. Take the train from Roma Termini to Florence Santa Maria Novellatrain train
    4. Take the train from Firenze S.M.N. to Sienatrain train Re
    19h 11m
    €73–183
  4. Drive, ferry

    1. Drive from Comiso to Messina Marittimacar car
    2. Take the ferry from Messina Marittima to Villa San Giovanniferry ferry
    3. Drive from Villa San Giovanni to Sienacar car
    11h 2m
    €161–245
  5. Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train

    1. Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stopbus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane plane CTA - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 10m
    €49–196
  6. Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train

    1. Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stopbus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane plane CTA - PSA
    3. Take the train from Pisa Centrale to Empolitrain train
    4. Take the train from Empoli to Sienatrain train
    8h 2m
    €74–214
  7. Fly Vincenzo Magliocco Airport to Florence Peretola Airport, train

    1. Fly from Vincenzo Magliocco Airport (CIY) to Florence Peretola Airport (FLR)plane plane CIY - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    6h 37m
    €104–324
  8. Bus to Catania–Fontanarossa Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stopbus bus
    2. Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)plane plane CTA - BLQ
    3. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    9h 6m
    €67–238
  9. Bus

    1. Take the bus from Licata Piazzale Martiri Delle Foibe to Florence Villa Constanza Bus Stationbus bus Autoservizi Salemi 700
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    21h 20m
  10. Train, bus

    1. Take the train from Comiso to Siracusatrain train Re
    2. Take the train from Siracusa to Firenze S.M.N.train train
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    21h 59m

Comiso to Siena by bus

Calendar22Weekly Buses
Duration18hAverage Duration
Ticket€36Cheapest Price
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Questions & Answers

What companies run services between Comiso, Italy and Siena, Italy?

You can take a bus from Comiso to Siena via Ragusa Bus Terminal, Aeroporto Vincenzo Bellini/Fontanarossa, and Catania Airport in around 18h. Alternatively, you can take a train from Comiso to Siena via Siracusa, Roma Termini, and Firenze S.M.N. in around 19h 11m.

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