There are 11 ways to get from Comiso to Siena by plane, train, bus, night train, train (Trenitalia), car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Vincenzo Magliocco Airport to Fiumicino International Airport, train
best- Fly from Vincenzo Magliocco Airport (CIY) to Fiumicino International Airport (FCO)plane CIY - FCO
- Take the train from Roma Termini to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
5h 46m€90–412Bus to Catania–Fontanarossa Airport, fly to Florence Peretola Airport, train
cheapest- Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stopbus
- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)plane CTA - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 52m€46–212Bus, train
- Take the bus from Gela Bus Station to Catania Central Bus Stationbus
- Take the bus from Catania to Villa San Giovannibus 582 / ...
- Take the train from Villa S.Giovanni to Napoli Afragolatrain Fr
- Take the train from Napoli Afragola to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
16h 16m€126–254Bus via Catania Airport (CTA)
- Take the bus from Ragusa Bus Terminal to Aeroporto Vincenzo Bellini/Fontanarossabus Ragusa
- Take the bus from Catania Airport to Sienabus N597 / ...
18h€54–152Bus, night train, train
- Take the bus from Comiso to Cataniabus
- Take the nighttrain from Catania Centrale to Firenze Campo Martenighttrain Ini
- Take the train from Firenze S.M.N. to Sienatrain Re
22h 4m€113–190Fly Vincenzo Magliocco Airport to Florence Peretola Airport, train
- Fly from Vincenzo Magliocco Airport (CIY) to Florence Peretola Airport (FLR)plane CIY - FLR
- Take the train from Firenze S.M.N. to Sienatrain
5h 56m€146–523Bus to Catania–Fontanarossa Airport, fly to Pisa International Airport, train
- Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stopbus
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)plane CTA - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 49m€62–240Bus to Catania–Fontanarossa Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stopbus
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)plane CTA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 32m€47–232Train (Trenitalia)
- Take the train from Comiso to Caltanissetta Xirbitrain
- Take the train from Caltanissetta Xirbi to Termini Imeresetrain
- Take the train from Termini Imerese to Roma Terminitrain Ic
- Take the train from Roma Termini to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
19h 48m€158–291Bus
- Take the bus from Gela Bus Station to Florence Villa Constanza Bus Stationbus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131R / ...
21h 19m€191–264Drive, car ferry
- Drive from Comiso to Tresmestiericar
- Take the carferry from Tresmestieri to Villa S. Giovannicarferry
- Drive from Villa S. Giovanni to Sienacar
11h 10m€188–288
Comiso to Siena by train and bus
Comparing Your Travel Options
The cheapest way to get from Comiso to Siena is to bus via Catania Airport (CTA) which costs €50 - €160 and takes 18h.
The fastest way to get from Comiso to Siena is to fly and train which takes 5h 46m and costs €90 - €420.
No, there is no direct bus from Comiso to Siena. However, there are services departing from Comiso and arriving at Siena via Ragusa Bus Terminal and Catania Airport. The journey, including transfers, takes approximately 18h.
No, there is no direct train from Comiso to Siena. However, there are services departing from Comiso and arriving at Siena via Caltanissetta Xirbi, Termini Imerese, Roma Termini and Firenze S.M.N.. The journey, including transfers, takes approximately 19h 48m.
The distance between Comiso and Siena is 962 km.
The best way to get from Comiso to Siena without a car is to bus and train which takes 16h 16m and costs €120 - €260.
It takes approximately 5h 46m to get from Comiso to Siena, including transfers.
Comiso to Siena bus services, operated by Interbus, depart from Ragusa Bus Terminal station.
Comiso to Siena train services, operated by Trenitalia, depart from Comiso station.
The best way to get from Comiso to Siena is to bus via Catania Airport (CTA) which takes 18h and costs €50 - €160. Alternatively, you can train, which costs €150 - €300 and takes 19h 48m.
What companies run services between Comiso, Italy and Siena, Italy?
You can take a bus from Comiso to Siena via Ragusa Bus Terminal, Aeroporto Vincenzo Bellini/Fontanarossa, and Catania Airport in around 18h. Alternatively, you can take a train from Comiso to Siena via Caltanissetta Xirbi, Termini Imerese, Roma Termini, and Firenze S.M.N. in around 19h 48m.
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €35–190
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €35–210
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Bari
- Ave. Duration
- 3h 50m
- When
- Monday, Wednesday, Thursday, and Saturday
- Estimated price
- €35–210
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Malta
- Ave. Duration
- 3h 50m
- When
- Tuesday
- Estimated price
- €35–210
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €90–190
Flights from Vincenzo Magliocco Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- €120–490
Flights from Vincenzo Magliocco Airport to Florence Peretola Airport via Milan Linate, Fiumicino International Airport
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- €200–850
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Fiumicino International Airport
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- €85–210
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €16–110
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €90–190
Flights from Vincenzo Magliocco Airport to Florence Peretola Airport via Fiumicino International Airport
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- €120–490
Flights from Vincenzo Magliocco Airport to Florence Peretola Airport via Milan Linate, Fiumicino International Airport
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- €200–850
- Website
- aeroitalia.com
Flights from Vincenzo Magliocco Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–270
- Website
- flyulendo.com
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- €15–95
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €35–190
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 42m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 5m
- Frequency
- Hourly
- Estimated price
- €55–100
- Website
- Trenitalia Frecce
Train from Napoli Afragola to Firenze S.M.N.
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €65–110
- Website
- Trenitalia Frecce
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 20 minutes
- Estimated price
- €12–22
- Website
- Trenitalia Frecce
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 1h 42m
- Frequency
- Every 20 minutes
- Estimated price
- €35–65
- Website
- Trenitalia Frecce
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- Every 3 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 15 minutes
- Estimated price
- €5–8
- Website
- Trenitalia
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €7–11
- Website
- Trenitalia
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- €11–15
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Comiso to Caltanissetta Xirbi
- Ave. Duration
- 2h 17m
- Frequency
- 5 times a day
- Estimated price
- €18–26
- Website
- Trenitalia
Train from Caltanissetta Xirbi to Termini Imerese
- Ave. Duration
- 1h 2m
- Frequency
- Every 2 hours
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 40m
- Frequency
- Every 3 hours
- Estimated price
- €30–45
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 4h 57m
- Frequency
- 6 times a week
- Estimated price
- €45–85
- Website
- Trenitalia Intercity
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Twice daily
- Estimated price
- €9–18
- Website
- Trenitalia Intercity
Train from Termini Imerese to Roma Termini
- Ave. Duration
- 10h 44m
- Frequency
- 4 times a day
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
Train from Roma Termini to Firenze S.M.N.
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- €28–55
- Website
- Trenitalia Intercity
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Villa S.Giovanni to Napoli Afragola
- Ave. Duration
- 5h 38m
- Frequency
- Once daily
- Estimated price
- €50–85
- Website
- Italo Treno
Train from Napoli Afragola to Firenze S.M.N.
- Ave. Duration
- 3h 17m
- Frequency
- 3 times a day
- Estimated price
- €55–95
- Website
- Italo Treno
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 38 min
- Frequency
- 5 times a day
- Estimated price
- €11–18
- Website
- Italo Treno
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Catania Centrale to Firenze Campo Marte
- Ave. Duration
- 15h 19m
- Frequency
- Twice daily
- Estimated price
- €85–150
- Website
- Trenitalia ICN
- Phone
- +39 06 164160
- info@etnatrasporti.it
- Website
- etnatrasporti.it
Bus from Gela Bus Station to Catania Central Bus Station
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
Bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
Bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
Bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Every 3 hours
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Catania to Villa San Giovanni
- Ave. Duration
- 2h 13m
- Frequency
- 4 times a day
- Estimated price
- €9–14
- Website
- Flixbus
Bus from Catania Airport to Siena
- Ave. Duration
- 13h 45m
- Frequency
- Twice daily
- Estimated price
- €85–140
- Website
- Flixbus
Bus from Comiso to Catania
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- €15–24
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Catania to Villa San Giovanni
- Ave. Duration
- 2h 14m
- Frequency
- Twice daily
- Estimated price
- €5–10
- Website
- Itabus S.p.A.
Bus from Catania Airport to Siena
- Ave. Duration
- 14h 55m
- Frequency
- Once daily
- Estimated price
- €50–95
- Website
- Itabus S.p.A.
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Catania to Villa San Giovanni
- Ave. Duration
- 2h 31m
- Frequency
- Once daily
- Estimated price
- €6–9
- Schedules at
- autoservizisalemi.it
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Ragusa Bus Terminal to Aeroporto Vincenzo Bellini/Fontanarossa
- Ave. Duration
- 1h 45m
- Frequency
- Every 3 hours
- Estimated price
- €4–12
- Schedules at
- interbus.it
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Gela Bus Station to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 48m
- Frequency
- Twice a week
- Estimated price
- €180–250
- Website
- Onebus
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Schedules at
- at-bus.it
- Phone
- 090774409
- info@bluferries.it
- Website
- bluferries.it
Car ferry from Tresmestieri to Villa S. Giovanni
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
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Booking & Getting There
Comiso to Siena bus services, operated by Interbus, arrive at Aeroporto Vincenzo Bellini/Fontanarossa station.
Comiso to Siena train services, operated by Trenitalia, arrive at Caltanissetta Xirbi station.
Book your Comiso to Siena train tickets online with Omio.
Book your Comiso to Siena bus tickets online with Omio.
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