There are 6 ways to get from Comiso to Assisi by plane, train, bus, train (Trenitalia), night train, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, train
best- Fly from Vincenzo Magliocco Airport (CIY) to Fiumicino International Airport (FCO)plane CIY - FCO
- Take the train from Roma Termini to Assisitrain
6h 25m€70–369Bus
cheapest- Take the bus from Ragusa Bus Terminal to Catania Via Archimedebus
- Take the bus from Catania Via D'Amico to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietrobus
18h 25m€57–83Train (Trenitalia)
- Take the train from Comiso to Caltanissetta Xirbitrain
- Take the train from Caltanissetta Xirbi to Termini Imeresetrain
- Take the train from Termini Imerese to Roma Terminitrain Ic
- Take the train from Roma Termini to Assisitrain
20h 13m€137–248Bus, night train, train
- Take the bus from Comiso to Cataniabus
- Take the nighttrain from Catania Centrale to Roma Termininighttrain Ini
- Take the train from Roma Termini to Assisitrain
20h 21m€100–181Bus via Palermo
- Take the bus from Comiso to Palermobus
- Take the bus from Palermo to Roma, Autostazione Tiburtinabus
- Take the bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietrobus
22h 40mDrive, car ferry
- Drive from Comiso to Tresmestiericar
- Take the carferry from Tresmestieri to Villa S. Giovannicarferry
- Drive from Villa S. Giovanni to Assisicar
11h 31m€178–268
Comiso to Assisi by bus
Comparing Your Travel Options
The cheapest way to get from Comiso to Assisi is to bus which costs €55 - €85 and takes 18h 25m.
The fastest way to get from Comiso to Assisi is to fly and train which takes 6h 25m and costs €70 - €370.
No, there is no direct bus from Comiso to Assisi. However, there are services departing from Comiso and arriving at Assisi - Piazza San Pietro via Ragusa Bus Terminal, Catania Via D'Amico and Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 18h 25m.
No, there is no direct train from Comiso to Assisi. However, there are services departing from Comiso and arriving at Assisi via Caltanissetta Xirbi, Termini Imerese and Roma Termini. The journey, including transfers, takes approximately 20h 13m.
The distance between Comiso and Assisi is 780 km.
The best way to get from Comiso to Assisi without a car is to bus which takes 18h 25m and costs €55 - €85.
It takes approximately 6h 25m to get from Comiso to Assisi, including transfers.
Comiso to Assisi bus services, operated by Interbus, depart from Ragusa Bus Terminal station.
Comiso to Assisi train services, operated by Trenitalia, depart from Comiso station.
The best way to get from Comiso to Assisi is to bus which takes 18h 25m and costs €55 - €85. Alternatively, you can train, which costs €130 - €250 and takes 20h 13m.
What companies run services between Comiso, Italy and Assisi, Italy?
You can take a bus from Comiso to Assisi - Piazza San Pietro via Ragusa Bus Terminal, Catania Via Archimede, Catania Via D'Amico, and Roma, Autostazione Tiburtina in around 18h 25m. Alternatively, you can take a train from Comiso to Via San Francesco via Caltanissetta Xirbi, Termini Imerese, Roma Termini, Assisi, and Assisi Stazione in around 20h 13m.
- Website
- aeroitalia.com
Flights from Vincenzo Magliocco Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €35–270
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 6m
- Frequency
- 5 times a day
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Comiso to Caltanissetta Xirbi
- Ave. Duration
- 2h 17m
- Frequency
- Twice daily
- Estimated price
- €18–26
- Website
- Trenitalia
Train from Caltanissetta Xirbi to Termini Imerese
- Ave. Duration
- 1h 2m
- Frequency
- Every 4 hours
- Estimated price
- €10–15
- Website
- Trenitalia
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 6m
- Frequency
- 5 times a day
- Estimated price
- €19–27
- Website
- Trenitalia
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 6m
- Frequency
- 5 times a day
- Estimated price
- €19–27
- Website
- Trenitalia
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- €18–35
- Website
- Trenitalia Intercity
Train from Termini Imerese to Roma Termini
- Ave. Duration
- 10h 44m
- Frequency
- Twice daily
- Estimated price
- €90–170
- Website
- Trenitalia Intercity
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- €18–35
- Website
- Trenitalia Intercity
Train from Roma Termini to Assisi
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- €18–35
- Website
- Trenitalia Intercity
- Phone
- 06 3000
- Website
- Trenitalia ICN
Night train from Catania Centrale to Roma Termini
- Ave. Duration
- 11h 27m
- Frequency
- Once daily
- Estimated price
- €65–120
- Website
- Trenitalia ICN
- Phone
- +39 0935 22 460
- Website
- interbus.it
Bus from Ragusa Bus Terminal to Catania Via Archimede
- Ave. Duration
- 1h 55m
- Frequency
- Every 3 hours
- Estimated price
- €4–13
- Schedules at
- interbus.it
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Catania Via D'Amico to Roma, Autostazione Tiburtina
- Ave. Duration
- 10h 15m
- Frequency
- Once daily
- Estimated price
- €30–45
- Schedules at
- autoservizisalemi.it
- Phone
- +39 075 5009641
- info@sulga.it
- Website
- sulga.it
Bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietro
- Ave. Duration
- 2h 45m
- Frequency
- 6 times a week
- Estimated price
- €23–26
- Schedules at
- sulga.it
- 2nd Class
- €23–26
Bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietro
- Ave. Duration
- 2h 45m
- Frequency
- 6 times a week
- Estimated price
- €23–26
- Schedules at
- sulga.it
- 2nd Class
- €23–26
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Comiso to Catania
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- €15–24
- Website
- Flixbus
Bus from Palermo to Roma, Autostazione Tiburtina
- Ave. Duration
- 14h 20m
- Frequency
- 5 times a week
- Estimated price
- €85–140
- Website
- Flixbus
- Phone
- +39 091-6208000
- info@astsicilia.it
- Website
- aziendasicilianatrasporti.it
Bus from Comiso to Palermo
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Schedules at
- aziendasicilianatrasporti.it
- Phone
- 090774409
- info@bluferries.it
- Website
- bluferries.it
Car ferry from Tresmestieri to Villa S. Giovanni
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Getting to Rome from the airport
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Comiso to Assisi bus services, operated by Interbus, arrive at Catania Via Archimede station.
Comiso to Assisi train services, operated by Trenitalia, arrive at Caltanissetta Xirbi station.
There are 2385+ hotels available in Assisi.


































