There are 8 ways to get from Comiso to Assisi by plane, train, train (Trenitalia), bus, car, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Vincenzo Magliocco Airport to Fiumicino International Airport, train
best- Fly from Vincenzo Magliocco Airport (CIY) to Fiumicino International Airport (FCO)CIY - FCO
- Take the train from Roma Termini to Foligno
6h 38m€59–374Bus
cheapest- Take the bus from Ragusa Via Scalo Merci to Catania Central Bus Station
- Take the bus from Catania to Roma, Autostazione Tiburtina
- Take the bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietro
19h 53m€53–137Train via Foligno
- Take the train from Comiso to SiracusaRe
- Take the train from Siracusa to Roma TerminiIc
- Take the train from Roma Termini to Foligno
19h 18m€61–175Drive, ferry
- Drive from Comiso to Messina Marittima
- Take the ferry from Messina Marittima to Villa San Giovanni
- Drive from Villa San Giovanni to Assisi
11h 23m€151–236Bus to Catania–Fontanarossa Airport, fly to Perugia Sant'Egidio Airport
- Take the bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stop
- Fly from Catania–Fontanarossa Airport (CTA) to Perugia Sant'Egidio Airport (PEG)CTA - PEG
5h 25m€90–399Train, train to Palermo Airport, fly to Perugia Sant'Egidio Airport
- Take the train from Comiso to Caltanissetta Xirbi
- Take the train from Caltanissetta Xirbi to Palermo Centrale
- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)PMO - PEG
8h 41m€121–473Train
- Take the train from Comiso to SiracusaRe
- Take the train from Siracusa to Roma Tiburtina
- Take the train from Roma Tiburtina to Assisi
19h 51m€60–209Bus via Rome Airport (FCO)
- Take the bus from Comiso to Catania Airport
- Take the bus from Catania Fontanarossa Airport Bus Stop to Fiumicino Aeroporto T3
- Take the bus from Fiumicino Aeroporto T3 to Assisi - Piazza San Pietro
26h 30m€58–128
Comiso to Assisi by train and bus
Questions & Answers
The cheapest way to get from Comiso to Assisi is to bus via Rome Airport (FCO) which costs €55 - €130 and takes 26h 30m.
The fastest way to get from Comiso to Assisi is to bus and fly which takes 5h 25m and costs €90 - €400.
No, there is no direct bus from Comiso to Assisi. However, there are services departing from Comiso and arriving at Assisi - Piazza San Pietro via Ragusa Via Scalo Merci, Catania and Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 19h 53m.
The distance between Comiso and Assisi is 781 km.
The best way to get from Comiso to Assisi without a car is to train via Foligno which takes 19h 18m and costs €60 - €180.
It takes approximately 6h 38m to get from Comiso to Assisi, including transfers.
Comiso to Assisi bus services, operated by Etna Trasporti, depart from Ragusa Via Scalo Merci station.
The best way to get from Comiso to Assisi is to train via Foligno which takes 19h 18m and costs €60 - €180. Alternatively, you can bus, which costs €50 - €140 and takes 19h 53m.
Comiso to Assisi bus services, operated by Etna Trasporti, arrive at Catania Central Bus Station.
There are 2192+ hotels available in Assisi.
What companies run services between Comiso, Italy and Assisi, Italy?
You can take a train from Comiso to P.za U. Italia Assisi via Siracusa, Roma Termini, Foligno, Assisi, and Assisi Stazione in around 19h 18m. Alternatively, you can take a bus from Comiso to Assisi - Piazza San Pietro via Ragusa Via Scalo Merci, Catania Central Bus Station, Catania, and Roma, Autostazione Tiburtina in around 19h 53m.
- Website
- aeroitalia.com
Flights from Vincenzo Magliocco Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €30–420
- Website
- flexflight.dk
Flights from Vincenzo Magliocco Airport to Fiumicino International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- €30–420
- Website
- ryanair.com
Flights from Catania–Fontanarossa Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 30m
- When
- Monday and Saturday
- Estimated price
- €75–330
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €85–310
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 52m
- Frequency
- Every 2 hours
- Estimated price
- €14–25
- Website
- https://www.trenitalia.com/en.html
Train from Comiso to Siracusa
- Ave. Duration
- 2h 44m
- Frequency
- Twice daily
- Estimated price
- €9–26
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €18–26
Train from Comiso to Caltanissetta Xirbi
- Ave. Duration
- 2h 16m
- Frequency
- 6 times a week
- Estimated price
- €9–29
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €20–29
Train from Caltanissetta Xirbi to Palermo Centrale
- Ave. Duration
- 1h 28m
- Frequency
- 5 times a day
- Estimated price
- €8–24
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €16–24
Train from Siracusa to Roma Tiburtina
- Ave. Duration
- 11h 55m
- Frequency
- Twice a week
- Estimated price
- €40–150
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €100–150
Train from Roma Tiburtina to Assisi
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- €10–30
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €21–30
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 54m
- Frequency
- 3 times a day
- Estimated price
- €9–23
- Website
- https://www.trenitalia.com/en.html
Train from Siracusa to Roma Termini
- Ave. Duration
- 11h 9m
- Frequency
- Once daily
- Estimated price
- €40–100
- Website
- https://www.trenitalia.com/en.html
Train from Roma Tiburtina to Assisi
- Ave. Duration
- 1h 52m
- Frequency
- 6 times a week
- Estimated price
- €17–25
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Foligno
- Ave. Duration
- 1h 42m
- Frequency
- Once daily
- Estimated price
- €23–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 164160
- info@etnatrasporti.it
- Website
- etnatrasporti.it
Bus from Ragusa Via Scalo Merci to Catania Central Bus Station
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €6–9
- Schedules at
- etnatrasporti.it
Bus from Gela Bus Station to Catania Fontanarossa Airport Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €6–8
- Schedules at
- etnatrasporti.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Ragusa Via Scalo Merci to Catania Central Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- €10–15
- Website
- https://www.flixbus.co.uk
Bus from Catania to Roma, Autostazione Tiburtina
- Ave. Duration
- 12h 5m
- Frequency
- Twice daily
- Estimated price
- €21–85
- Website
- https://www.flixbus.co.uk
Bus from Comiso to Catania Airport
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- €15–22
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Catania to Roma, Autostazione Tiburtina
- Ave. Duration
- 11h 30m
- Frequency
- Twice daily
- Estimated price
- €20–90
- Website
- https://www.itabus.it/en/home
Bus from Catania Fontanarossa Airport Bus Stop to Fiumicino Aeroporto T3
- Ave. Duration
- 16h 45m
- Frequency
- 6 times a week
- Estimated price
- €19–80
- Website
- https://www.itabus.it/en/home
- Phone
- +39 075 5009641
- info@sulga.it
- Website
- sulga.it
Bus from Roma, Autostazione Tiburtina to Assisi - Piazza San Pietro
- Ave. Duration
- 2h 45m
- Frequency
- 6 times a week
- Estimated price
- €23–26
- Schedules at
- sulga.it
- 2nd Class
- €23–26
Bus from Fiumicino Aeroporto T3 to Assisi - Piazza San Pietro
- Ave. Duration
- 4h 15m
- Frequency
- 6 times a week
- Estimated price
- €23–27
- Schedules at
- sulga.it
- 2nd Class
- €23–27
- Phone
- 342 32 55 869
- Website
- blujetlines.it
Ferry from Messina Marittima to Villa San Giovanni
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Estimated price
- €2–3
- Schedules at
- blujetlines.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Getting to Rome from the airport
Read the travel guide
Want to know more about Flixbus?
Read the travel guide

























