There are 4 ways to get from Columbus to Knoxville by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  7 h 27 min

  1. Take the bus from Columbus, Oh to Cincinnati, Oh 1117 / ...
  2. Take the bus from Cincinnati, Oh to Knoxville, Tn 1109 / ...

$46 - $113

Cheapest option

Bus via Cincinnati, OH  •  7 h 28 min

  1. Take the bus from Columbus, OH to Cincinnati, OH Schedules 0010 and 0011
  2. Take the bus from Cincinnati, Oh to Knoxville, Tn 1109 / ...

$45 - $103

2 alternative options

Drive  •  5 h 57 min

  1. Drive from Columbus to Knoxville 360.2 miles

$35 - $55

Fly  •  4 h 58 min

  1. Fly from Columbus (CMH) to Knoxville (TYS) CMH - TYS

$248 - $1,075

Questions & Answers

The cheapest way to get from Columbus to Knoxville is to drive which costs $35 - $55 and takes 5 h 57 min.

More details

The quickest way to get from Columbus to Knoxville is to fly which costs $240 - $1,100 and takes 4 h 58 min.

More details

The distance between Columbus and Knoxville is 283 miles. The road distance is 360.2 miles.

Get driving directions

It takes approximately 7 h 27 min to get from Columbus to Knoxville, including transfers.

More details

No, there is no direct bus from Columbus to Knoxville. However, there are services departing from Columbus, Oh and arriving at Knoxville, Tn via Cincinnati, Oh. The journey, including transfers, takes approximately 7 h 27 min.

More details

What companies run services between Columbus, OH, USA and Knoxville, TN, USA?

You can take a bus from Columbus to Knoxville via Cincinnati, Oh in around 7 h 27 min. Alternatively, American Airlines, Delta and United Airlines fly from Columbus to Knoxville hourly.

Airlines
Delta
Website
delta.com
Flights from Columbus to Knoxville via Atlanta
Ave. Duration
4 h 6 min
When
Every day
Estimated price
$190 - $1,000
Flights from Columbus to Knoxville via Detroit
Ave. Duration
3 h 49 min
When
Every day
Estimated price
$190 - $1,000
American Airlines
Website
aa.com
Flights from Columbus to Knoxville via Charlotte
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$200 - $1,000
Flights from Columbus to Knoxville via Chicago O'Hare
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$220 - $1,100
Flights from Columbus to Knoxville via Reagan Washington
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$220 - $1,100
Flights from Columbus to Knoxville via Philadelphia
Ave. Duration
4 h 38 min
When
Every day
Estimated price
$240 - $1,100
United Airlines
Website
united.com
Flights from Columbus to Knoxville via Washington Dulles
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$230 - $1,100
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbus, Oh to Cincinnati, Oh
Ave. Duration
1 h 55 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$29 - $40
Bus from Cincinnati, Oh to Knoxville, Tn
Ave. Duration
5 h 20 min
Frequency
Every 30 minutes
Estimated price
$29 - $75
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $75

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