There are 3 ways to get from Columbus to Great Smoky Mountains by plane, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly, drive  •  6 h 32 min

  1. Fly from Columbus (CMH) to Knoxville (TYS) CMH - TYS
  2. Drive from Knoxville to Great Smoky Mountains

$199 - $1,015

Cheapest option

Bus, drive  •  16 h 33 min

  1. Take the bus from Columbus, Oh to Winston Salem, Nc
  2. Take the bus from Winston Salem, Nc to Asheville, Nc
  3. Drive from Asheville, Nc to Great Smoky Mountains

$71 - $168

1 alternative option

Drive  •  7 h 40 min

  1. Drive from Columbus to Great Smoky Mountains 424.8 miles

$40 - $60

Questions & Answers

The cheapest way to get from Columbus to Great Smoky Mountains is to drive which costs $40 - $60 and takes 7 h 40 min.

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The quickest way to get from Columbus to Great Smoky Mountains is to fly and drive which costs $190 - $1,100 and takes 6 h 32 min.

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The distance between Columbus and Great Smoky Mountains is 306 miles. The road distance is 424.8 miles.

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It takes approximately 6 h 32 min to get from Columbus to Great Smoky Mountains, including transfers.

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There is no direct flight from Columbus Airport to Knoxville Airport. The quickest flight takes 3 h 24 min and has one stopover.

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Yes, the driving distance between Columbus to Great Smoky Mountains is 425 miles. It takes approximately 7 h 40 min to drive from Columbus to Great Smoky Mountains.

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United Airlines, American Airlines and Delta offer flights from Columbus Airport to Knoxville Airport.

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There are 1268+ hotels available in Great Smoky Mountains. Prices start at $69 USD per night.

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Map of how to get from Columbus to Great Smoky Mountains.
Launch map view
  • Distance: 305.5 miles
  • Duration: 6 h 32 min

What companies run services between Columbus, OH, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Columbus to Great Smoky Mountains. However, you can take the bus to Columbus, OH - Airport, take the walk to Columbus airport, fly to Knoxville, then take the drive to Great Smoky Mountains. Alternatively, you can take the bus to Winston Salem, Nc, take the bus to Asheville, Nc, then take the drive to Great Smoky Mountains.

Airlines
Delta
Website
delta.com
Flights from Columbus to Knoxville via Atlanta
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$190 - $1,000
Flights from Columbus to Knoxville via Detroit
Ave. Duration
4 h 13 min
When
Every day
Estimated price
$190 - $1,000
American Airlines
Website
aa.com
Flights from Columbus to Knoxville via Charlotte
Ave. Duration
4 h 7 min
When
Every day
Estimated price
$200 - $1,000
Flights from Columbus to Knoxville via Chicago O'Hare
Ave. Duration
4 h 3 min
When
Every day
Estimated price
$220 - $1,100
Flights from Columbus to Knoxville via Reagan Washington
Ave. Duration
4 h 4 min
When
Every day
Estimated price
$220 - $1,100
United Airlines
Website
united.com
Flights from Columbus to Knoxville via Washington Dulles
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$230 - $1,100
Flights from Columbus to Knoxville via Newark
Ave. Duration
4 h 34 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,200
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbus, Oh to Winston Salem, Nc
Ave. Duration
10 h 35 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50

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