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How to get fromColorado to St. Louisby plane, bus (Greyhound), train (Amtrak), car or taxi

Find Transport to St. Louis

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There are 6 ways to get from Colorado to St. Louis by plane, bus (Greyhound), train (Amtrak), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Denver

    best
    1. Fly from Denver (DEN) to Lambert–St. Louis International Airport (STL)plane plane DEN - STL
    4h 47m
    $146–766

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Denver Union Station to St Louis Bus Stationbus bus Greyhound US1200
    16h 33m
    $77–169

  3. Train (Amtrak)

    1. Take the train from Denver to Chicago Union Stationtrain train California Zephyr
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    24h 26m
    $142–482

  4. Drive 844.6 mi

    1. Drive from Denver to St. Louiscar car 844.6 mi
    13h 30m
    $155–223

  5. Taxi to Cheyenne Airport, fly

    1. Take the taxi from Fort Collins to Cheyenne-Airport-CYStaxi taxi
    2. Fly from Cheyenne Airport (CYS) to Lambert–St. Louis International Airport (STL)plane plane CYS - STL
    7h 35m
    $244–845

  6. Fly from Colorado Springs Airport

    1. Fly from Colorado Springs Airport (COS) to Lambert–St. Louis International Airport (STL)plane plane COS - STL
    6h 44m
    $197–1,007

Colorado to St. Louis by train (Amtrak)

Calendar7Weekly Trains
Duration24h 26mAverage Duration
Ticket$142Cheapest Price
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Questions & Answers

What companies run services between Colorado, USA and St. Louis, MO, USA?

Frontier Airlines, United Airlines, and Southwest Airlines fly from Denver (DEN) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, Greyhound USA operates a bus from Denver Union Station to St Louis Bus Station once daily. Tickets cost $70–160 and the journey takes 16h 30m.

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Need to know: Greyhound

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