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How to get fromColorado to Indianaby plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

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There are 7 ways to get from Colorado to Indiana by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Denver to Indianapolis

    best
    1. Fly from Denver (DEN) to Indianapolis (IND)plane plane DEN - IND
    5h 33m
    $95–319
  2. Fly Colorado Springs Airport to Chicago O'Hare International Airport, train

    cheapest
    1. Fly from Colorado Springs Airport (COS) to Chicago O'Hare International Airport (ORD)plane plane COS - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 56m
    $79–359
  3. Train (Amtrak)

    1. Take the train from Denver to Chicago Union Stationtrain train California Zephyr
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    25h 47m
    $668–1,041
  4. Bus

    1. Take the bus from Denver Union Station to Chicago Bus Stationbus bus Greyhound US0123S
    2. Take the bus from Chicago Bus Station to Indianapolisbus bus FlixBus 2511 / ...
    26h 28m
    $214–317
  5. Drive  1,078.3 mi

    1. Drive from Denver to Indianapoliscar car 1,078.3 mi
    17h 18m
    $178–258
  6. Fly Denver to Chicago Midway International Airport, train

    1. Fly from Denver (DEN) to Chicago Midway International Airport (MDW)plane plane DEN - MDW
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 17m
    $175–247
  7. Fly Denver to Chicago O'Hare International Airport, train

    1. Fly from Denver (DEN) to Chicago O'Hare International Airport (ORD)plane plane DEN - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    6h 36m
    $96–289

Colorado to Indiana by bus and train (Amtrak)

Calendar3Weekly Services
Duration25h 47mAverage Duration
Ticket$668Cheapest Price
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Comparing Your Travel Options

What companies run services between Colorado, USA and Indiana, USA?

Frontier Airlines, United Airlines, and three other airlines fly from Denver (DEN) to Indianapolis (IND) hourly. Alternatively, you can take a bus from Civic Center Loop to Indianapolis via 16th Street & Wewatta St, Denver, and Chicago Union Station in around 25h 47m.

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Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There