There are 8 ways to get from Cleveland to Tupelo by plane, car, train, bus, bus (Greyhound, Flixbus), or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Golden Triangle Regional Airport, drive
best- Fly from Cleveland-Hopkins International Airport (CLE) to Golden Triangle Regional Airport (GTR)plane CLE - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
8h 32m$162–518Fly to Tupelo Regional Airport
cheapest- Fly from Cleveland-Hopkins International Airport (CLE) to Tupelo Regional Airport (TUP)plane CLE - TUP
8h 20m$106–570Train, bus
- Take the train from Cleveland Amtrak to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
20h 14m$302–479Train, bus via St. Louis
- Take the train from Cleveland Amtrak to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Louistrain
- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
21h 46m$412–649Drive 714 mi
- Drive from Cleveland to Tupelocar 714 mi
13h 7m$122–177Fly to Memphis, bus
- Fly from Cleveland-Hopkins International Airport (CLE) to Memphis (MEM)plane CLE - MEM
- Take the bus from Memphis Bus Station to Tupelobus
9h 14m$212–1,144Bus via Chicago
- Take the bus from Cleveland to Chicagobus
- Take the bus from Chicago Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
20h 54m$151–273Bus (Greyhound)
- Take the bus from Cleveland Bus Station to Atlanta Bus Stationbus Greyhound US0105
- Take the bus from Atlanta Bus Station to Tupelobus Greyhound US0610
29h$204–312
Cleveland-Hopkins International Airport (CLE) to Golden Triangle Regional Airport (GTR) flights
Comparing Your Travel Options
The cheapest way to get from Cleveland to Tupelo is to drive which costs $120 - $180 and takes 13h 7m.
The fastest way to get from Cleveland to Tupelo is to fly which takes 8h 20m and costs $100 - $600.
No, there is no direct bus from Cleveland to Tupelo. However, there are services departing from Cleveland and arriving at Tupelo via Chicago Bus Station and Memphis Bus Station. The journey, including transfers, takes approximately 20h 54m.
The distance between Cleveland and Tupelo is 740 miles. The road distance is 718.2 miles.
The best way to get from Cleveland to Tupelo without a car is to train and bus which takes 20h 14m and costs $300 - $480.
It takes approximately 8h 32m to get from Cleveland to Tupelo, including transfers.
Cleveland to Tupelo bus services, operated by Barons Bus, depart from Cleveland station.
The best way to get from Cleveland to Tupelo is to fly which takes 8h 20m and costs $100 - $600. Alternatively, you can bus via Chicago, which costs $150 - $280 and takes 20h 54m.
Cleveland to Tupelo bus services, operated by Barons Bus, arrive at Chicago station.
Tupelo is 1h behind Cleveland. It is currently 12:39 AM in Cleveland and 11:39 PM in Tupelo.
What companies run services between Cleveland, OH, USA and Tupelo, MS, USA?
American Airlines, Corporate Flight Management Inc, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Tupelo Regional Airport (TUP) 4 times a day. Alternatively, you can take a bus from Cleveland to Tupelo via Chicago Bus Station, Memphis Bus Station, and Tupelo in around 20h 54m.
- Website
- delta.com
Flights from Cleveland-Hopkins International Airport to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $100–550
Flights from Cleveland-Hopkins International Airport to Golden Triangle Regional Airport via Detroit, Atlanta
- Ave. Duration
- 6h 54m
- When
- Every day
- Estimated price
- $110–600
Flights from Cleveland-Hopkins International Airport to Memphis via Detroit
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Cleveland-Hopkins International Airport to Memphis via Atlanta
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $220–1,200
- Website
- contouraviation.com
Flights from Cleveland-Hopkins International Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 45m
- When
- Every day
- Estimated price
- $160–750
Flights from Cleveland-Hopkins International Airport to Tupelo Regional Airport via Nashville
- Ave. Duration
- 7h 5m
- When
- Every day
- Estimated price
- $90–550
Flights from Cleveland-Hopkins International Airport to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 57m
- When
- Every day
- Estimated price
- $110–600
Flights from Cleveland-Hopkins International Airport to Tupelo Regional Airport via Detroit, Nashville
- Ave. Duration
- 7h 59m
- When
- Every day
- Estimated price
- $100–550
Flights from Cleveland-Hopkins International Airport to Tupelo Regional Airport via Charlotte, Nashville
- Ave. Duration
- 7h 49m
- When
- Sunday
- Estimated price
- $110–600
Flights from Cleveland-Hopkins International Airport to Tupelo Regional Airport via Chicago Midway, Nashville
- Ave. Duration
- 11h 10m
- When
- Sunday
- Estimated price
- $110–600
- Website
- aa.com
Flights from Cleveland-Hopkins International Airport to Golden Triangle Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 59m
- When
- Every day
- Estimated price
- $160–750
Flights from Cleveland-Hopkins International Airport to Memphis via Charlotte
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Cleveland-Hopkins International Airport to Memphis via Chicago O'Hare
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $200–1,100
- Website
- southwest.com
Flights from Cleveland-Hopkins International Airport to Memphis via Nashville
- Ave. Duration
- 3h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–1,100
Flights from Cleveland-Hopkins International Airport to Memphis via Chicago Midway
- Ave. Duration
- 4h 30m
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $200–1,100
Flights from Cleveland-Hopkins International Airport to Memphis via Baltimore
- Ave. Duration
- 5h 55m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $250–1,300
- Website
- united.com
Flights from Cleveland-Hopkins International Airport to Memphis via Chicago O'Hare
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $200–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Cleveland Amtrak to Chicago Union Station
- Ave. Duration
- 6h 46m
- Frequency
- 3 times a day
- Estimated price
- $180–290
- Website
- Amtrak
Train from Cleveland Amtrak to Chicago Union Station
- Ave. Duration
- 6h 46m
- Frequency
- 3 times a day
- Estimated price
- $180–290
- Website
- Amtrak
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Chicago Bus Station to Memphis Bus Station
- Ave. Duration
- 9h 35m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $18–27
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $18–27
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $18–27
- Website
- Greyhound
Bus from Chicago Bus Station to Memphis Bus Station
- Ave. Duration
- 9h 35m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $18–27
- Website
- Greyhound
Bus from Cleveland Bus Station to Atlanta Bus Station
- Ave. Duration
- 20h 30m
- Frequency
- Once daily
- Estimated price
- $140–220
- Website
- Greyhound
Bus from Atlanta Bus Station to Tupelo
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Memphis Bus Station
- Ave. Duration
- 11h
- Frequency
- 5 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- 5 times a week
- Estimated price
- $45–70
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Memphis Bus Station
- Ave. Duration
- 11h
- Frequency
- 5 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Cleveland to Chicago
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $35–85
- Website
- Barons Bus
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Cleveland to Tupelo is 718 miles. It takes approximately 13h 7m to drive from Cleveland to Tupelo.
Book your Cleveland to Tupelo bus tickets online with Omio.
There are 35+ hotels available in Tupelo.
















