There are 4 ways to get from Cleveland to Syracuse by train (Amtrak), bus (Greyhound, Flixbus), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from Cleveland Amtrak to Syracuse Regional Transportation Centertrain Lake Shore Limited
5h 38m$90–200Bus
cheapest- Take the bus from Cleveland, OH to Buffalo, NYbus Cinncinati,OH-Buffalo
- Take the bus from Buffalo to Syracuse Bus Stationbus FlixBus 2686 / ...
6h 37m$54–118Drive 333.9 mi
- Drive from Cleveland to Syracusecar 333.9 mi
5h 49m$61–88Fly
- Fly from Cleveland-Hopkins International Airport (CLE) to Syracuse Hancock International Airport (SYR)plane CLE - SYR
6h 48m$134–860
Cleveland to Syracuse by train (Amtrak)
Questions & Answers
The cheapest way to get from Cleveland to Syracuse is to drive which costs $60 - $90 and takes 5h 49m.
The fastest way to get from Cleveland to Syracuse is to train which takes 5h 38m and costs $90 - $200.
No, there is no direct bus from Cleveland to Syracuse station. However, there are services departing from Cleveland, OH and arriving at Syracuse Bus Station via Buffalo. The journey, including transfers, takes approximately 6h 37m.
Yes, there is a direct train departing from Cleveland Amtrak and arriving at Syracuse Regional Transportation Center. Services depart twice daily, and operate every day. The journey takes approximately 5h 38m.
The distance between Cleveland and Syracuse is 329 miles. The road distance is 335.8 miles.
The best way to get from Cleveland to Syracuse without a car is to train which takes 5h 38m and costs $90 - $200.
The train from Cleveland Amtrak to Syracuse Regional Transportation Center takes 5h 38m including transfers and departs twice daily.
Cleveland to Syracuse bus services, operated by Barons Bus, depart from Cleveland, OH station.
Cleveland to Syracuse train services, operated by Amtrak, depart from Cleveland Amtrak station.
The best way to get from Cleveland to Syracuse is to train which takes 5h 38m and costs $90 - $200. Alternatively, you can bus, which costs $50 - $120 and takes 6h 37m, you could also fly, which costs $130 - $900 and takes 6h 48m.
What companies run services between Cleveland, OH, USA and Syracuse, NY, USA?
Amtrak operates a train from Cleveland Amtrak to Syracuse Regional Transportation Center twice daily. Tickets cost $90–200 and the journey takes 5h 38m. Alternatively, you can take a bus from Cleveland, OH to Syracuse Bus Station via Buffalo, NY and Buffalo in around 6h 37m.
- Website
- delta.com
Flights from Cleveland-Hopkins International Airport to Syracuse Hancock International Airport via Detroit
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $130–850
Flights from Cleveland-Hopkins International Airport to Syracuse Hancock International Airport via New York La Guardia
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $150–900
Flights from Cleveland-Hopkins International Airport to Syracuse Hancock International Airport via New York JFK
- Ave. Duration
- 8h 2m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $160–900
- Website
- aa.com
Flights from Cleveland-Hopkins International Airport to Syracuse Hancock International Airport via Philadelphia
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $150–900
Flights from Cleveland-Hopkins International Airport to Syracuse Hancock International Airport via Reagan Washington
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $150–900
- Website
- united.com
Flights from Cleveland-Hopkins International Airport to Syracuse Hancock International Airport via Washington Dulles
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $150–900
Flights from Cleveland-Hopkins International Airport to Syracuse Hancock International Airport via Newark
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $150–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Cleveland Amtrak to Syracuse Regional Transportation Center
- Ave. Duration
- 5h 38m
- Frequency
- Twice daily
- Estimated price
- $90–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $18–60
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Cleveland, OH to Buffalo, NY
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 5m
- Frequency
- 4 times a day
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- $20–35
- Schedules at
- flixbus.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Buffalo to Syracuse Bus Station
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- $28–95
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $28–90
- Flexible
- $55–95
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Cleveland to Syracuse bus services, operated by Barons Bus, arrive at Buffalo, NY station.
Cleveland to Syracuse train services, operated by Amtrak, arrive at Syracuse Regional Transportation Center station.
Yes, the driving distance between Cleveland to Syracuse is 336 miles. It takes approximately 5h 49m to drive from Cleveland to Syracuse.
Book your Cleveland to Syracuse train tickets online with Omio.
Book your Cleveland to Syracuse bus tickets online with Omio and FlixBus.
There are 241+ hotels available in Syracuse.












