There are 8 ways to get from Cleveland to South Carolina by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Cleveland to Charlotte  •  3 h 37 min

  1. Fly from Cleveland (CLE) to Charlotte (CLT) CLE - CLT

$142 - $642

Cheapest option

Bus via Cleveland, OH  •  20 h 32 min

  1. Take the bus from Cleveland, OH to Columbus, OH
  2. Take the bus from Columbus, Oh to Columbia, Sc
  3. Take the bus from Columbia, SC to Florence, SC

$94 - $202

6 alternative options

Fly Cleveland to Greenville/Spartanburg  •  5 h 2 min

  1. Fly from Cleveland (CLE) to Greenville/Spartanburg (GSP) CLE - GSP

$212 - $998

Bus to Akron, fly to Charlotte  •  5 h 50 min

  1. Take the bus from Cleveland, Oh to Akron, Oh
  2. Fly from Akron (CAK) to Charlotte (CLT) CAK - CLT

$248 - $964

Fly Cleveland to Myrtle Beach, bus  •  5 h 51 min

  1. Fly from Cleveland (CLE) to Myrtle Beach (MYR) CLE - MYR
  2. Take the bus from Myrtle Beach to Florence, SC

$198 - $766

Train  •  19 h 51 min

  1. Take the train from Cleveland Amtrak to Washington Union Station Capitol Limited
  2. Take the train from Washington Union Station to Florence Amtrak Palmetto / ...

$134 - $364

Bus  •  20 h 2 min

  1. Take the bus from Cleveland, Oh to Columbus, Oh
  2. Take the bus from Columbus, Oh to Columbia, Sc
  3. Take the bus from Columbia, SC to Florence, SC

$94 - $214

Drive  •  10 h 55 min

  1. Drive from Cleveland to Florence 621.7 miles

$60 - $90

Questions & Answers

No, there is no direct bus from Cleveland to South Carolina. However, there are services departing from Cleveland, Oh and arriving at Florence, SC via Columbus, Oh and Columbia, SC. The journey, including transfers, takes approximately 20 h 2 min.

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No, there is no direct train from Cleveland to South Carolina. However, there are services departing from Cleveland Amtrak and arriving at Florence Amtrak via Washington Union Station. The journey, including transfers, takes approximately 19 h 51 min.

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The distance between Cleveland and South Carolina is 547 miles. The road distance is 621.7 miles.

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The best way to get from Cleveland to South Carolina without a car is to train which takes 19 h 51 min and costs .

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It takes approximately 3 h 37 min to get from Cleveland to South Carolina, including transfers.

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Cleveland to South Carolina bus services, operated by Greyhound USA, depart from Cleveland, Oh station.

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Cleveland to South Carolina train services, operated by Amtrak, depart from Cleveland Amtrak station.

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The best way to get from Cleveland to South Carolina is to fly which takes 3 h 37 min and costs . Alternatively, you can train, which costs and takes 19 h 51 min, you could also bus, which costs and takes 20 h 2 min.

Mode details

The quickest flight from Cleveland Airport to Charlotte Airport is the direct flight which takes 1 h 37 min.

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Cleveland to South Carolina bus services, operated by South Eastern Stages, arrive at Florence, SC station.

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Map of how to get from Cleveland to South Carolina.
Launch map view
  • Distance: 547.3 miles
  • Duration: 3 h 37 min

What companies run services between Cleveland, OH, USA and South Carolina, USA?

American Airlines, United Airlines and two other airlines fly from Cleveland to Rock Hill hourly. Alternatively, you can take a train from Cleveland to Florence via Washington Union Station in around 19 h 51 min.

Airlines
American Airlines
Website
aa.com
Flights from Cleveland to Charlotte
Ave. Duration
1 h 45 min
When
Every day
Estimated price
$270 - $650
Flights from Cleveland to Greenville/Spartanburg via Charlotte
Ave. Duration
3 h 37 min
When
Every day
Estimated price
$180 - $950
Flights from Cleveland to Greenville/Spartanburg via Philadelphia
Ave. Duration
4 h 31 min
When
Every day
Estimated price
$220 - $1,000
Flights from Akron to Charlotte
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$160 - $850
Flights from Akron to Charlotte via Philadelphia
Ave. Duration
4 h 9 min
When
Every day
Estimated price
$190 - $900
Flights from Cleveland to Myrtle Beach via Charlotte
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$300 - $1,500
Delta
Website
delta.com
Flights from Cleveland to Charlotte via Atlanta
Ave. Duration
3 h 52 min
When
Saturday
Estimated price
$170 - $650
Flights from Cleveland to Greenville/Spartanburg via Atlanta
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$190 - $950
Flights from Cleveland to Greenville/Spartanburg via Detroit
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$180 - $950
Flights from Akron to Charlotte via Atlanta
Ave. Duration
3 h 58 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $900
Flights from Cleveland to Myrtle Beach via Atlanta
Ave. Duration
3 h 51 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$320 - $1,600
Flights from Cleveland to Myrtle Beach via Detroit
Ave. Duration
3 h 52 min
When
Saturday
Estimated price
$300 - $1,500
United Airlines
Website
united.com
Flights from Cleveland to Charlotte via Washington Dulles
Ave. Duration
3 h 41 min
When
Every day
Estimated price
$260 - $1,300
Flights from Cleveland to Greenville/Spartanburg via Washington Dulles
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$210 - $1,000
Flights from Cleveland to Greenville/Spartanburg via Chicago O'Hare
Ave. Duration
4 h 32 min
When
Every day
Estimated price
$230 - $1,100
Flights from Cleveland to Greenville/Spartanburg via Newark
Ave. Duration
4 h 40 min
When
Monday, Tuesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Cleveland to Charlotte via Baltimore
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$180 - $800
Spirit Airlines
Website
spirit.com
Flights from Cleveland to Myrtle Beach
Ave. Duration
1 h 40 min
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$150 - $700
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Cleveland Amtrak to Washington Union Station
Ave. Duration
11 h 11 min
Frequency
Once daily
Estimated price
$65 - $190
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$300 - $410
Train from Washington Union Station to Florence Amtrak
Ave. Duration
7 h 40 min
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Cleveland, Oh to Akron, Oh
Ave. Duration
40 min
Frequency
Hourly
Estimated price
$10 - $23
Website
greyhound.com
Economy
$10 - $15
Flexible
$18 - $23
Bus from Cleveland, Oh to Columbus, Oh
Ave. Duration
2 h 25 min
Frequency
Every 30 minutes
Estimated price
$19 - $50
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $50
Bus from Columbus, Oh to Columbia, Sc
Ave. Duration
15 h 5 min
Frequency
Every 30 minutes
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $95
Flexible
$100 - $140
South Eastern Stages
Phone
+1 877.836.7607 / 404.591.2750
Email
info@sestages.com
Website
southeasternstages.com
Bus from Myrtle Beach to Florence, SC
Ave. Duration
1 h 30 min
Frequency
Once daily
Estimated price
$18 - $29
Schedules at
southeasternstages.com
Bus from Columbia, SC to Florence, SC
Ave. Duration
1 h 20 min
Frequency
3 times a day
Estimated price
$19 - $29
Schedules at
southeasternstages.com

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More Questions & Answers

Cleveland to South Carolina train services, operated by Amtrak, arrive at Florence Amtrak station.

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Yes, the driving distance between Cleveland to South Carolina is 622 miles. It takes approximately 10 h 55 min to drive from Cleveland to South Carolina.

Get driving directions

United Airlines, Delta, Southwest Airlines and American Airlines offer flights from Cleveland Airport to Charlotte Airport.

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Book your Cleveland to South Carolina train tickets online with Rome2rio.

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There are 17+ hotels available in South Carolina. Prices start at $51 USD per night.

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The best way to get from Cleveland to Cleveland Airport is to subway which takes 27 min and costs .

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