There are 6 ways to get from Cleveland to Mississauga by bus, train, car, plane, train (Amtrak), or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Cleveland to Buffalobus Bsb 10
- Take the bus from Buffalo to Mississaugabus Adt N816-D / ...
6h 37m$58–154Train, bus
- Take the train from Cleveland Amtrak to Buffalo Depew Stationtrain
- Take the train from Buffalo Depew Station to Niagara Fallstrain
- Take the bus from Niagara Falls to Mississaugabus
8h 6m$184–493Drive 441.8 km
- Drive from Cleveland to Mississaugacar 441.8 km
4h 51m$88–128Fly
- Fly from Cleveland-Hopkins International Airport (CLE) to Toronto Pearson International Airport (YYZ)plane CLE - YYZ
4h 12m$558–2,710Train
- Take the train from Cleveland Amtrak to Buffalo Depew Stationtrain Lake Shore Limited
- Take the train from Buffalo to Oakvilletrain VIA Rail
9h 6m$184–459Bus via Erie
- Take the bus from Cleveland Bus Station to Eriebus Greyhound US0170
- Take the bus from Erie to Torontobus FlixBus 2526
10h 29m$77–122
Cleveland to Mississauga by bus
Comparing Your Travel Options
The cheapest way to get from Cleveland to Mississauga is to bus via Erie which costs $75 - $130 and takes 10h 29m.
The fastest way to get from Cleveland to Mississauga is to fly which takes 4h 12m and costs $550 - $2,800.
No, there is no direct bus from Cleveland to Mississauga. However, there are services departing from Cleveland and arriving at City Centre Transit Terminal Platform A via Buffalo and Winston Churchill Station East Platform 6. The journey, including transfers, takes approximately 6h 37m.
No, there is no direct train from Cleveland to Mississauga. However, there are services departing from Cleveland Amtrak and arriving at Oakville via Buffalo. The journey, including transfers, takes approximately 9h 6m.
The distance between Cleveland and Mississauga is 449 km. The road distance is 441.8 km.
The best way to get from Cleveland to Mississauga without a car is to bus which takes 6h 37m and costs $55 - $160.
It takes approximately 6h 37m to get from Cleveland to Mississauga, including transfers.
Cleveland to Mississauga bus services, operated by Barons Bus, depart from Cleveland station.
Cleveland to Mississauga train services, operated by Amtrak, depart from Cleveland Amtrak station.
The best way to get from Cleveland to Mississauga is to bus which takes 6h 37m and costs $55 - $160. Alternatively, you can fly, which costs $550 - $2,800 and takes 4h 12m, you could also train, which costs $180 - $460 and takes 9h 6m.
What companies run services between Cleveland, OH, USA and Mississauga, ON, Canada?
You can take a bus from Cleveland to City Centre Transit Terminal Platform A via Buffalo and Winston Churchill Station East Platform 6 in around 6h 37m. Alternatively, Air Canada flies from Cleveland-Hopkins International Airport (CLE) to Toronto Pearson International Airport (YYZ) once daily.
- Website
- aircanada.com
Flights from Cleveland-Hopkins International Airport to Toronto Pearson International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $65–460
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Cleveland Amtrak to Buffalo Depew Station
- Ave. Duration
- 3h 3m
- Frequency
- Twice daily
- Estimated price
- $140–230
- Website
- Amtrak
Train from Buffalo Depew Station to Niagara Falls
- Ave. Duration
- 1h 36m
- Frequency
- Once daily
- Estimated price
- $26–40
- Website
- Amtrak
Train from Cleveland Amtrak to Buffalo Depew Station
- Ave. Duration
- 3h 3m
- Frequency
- Twice daily
- Estimated price
- $140–230
- Website
- Amtrak
- Phone
- +1 888 842-7245
- Website
- VIA Rail
Train from Buffalo Depew Station to Niagara Falls
- Ave. Duration
- 1h 36m
- Frequency
- Once daily
- Estimated price
- $12–210
- Website
- VIA Rail
- Escape
- $12–65
- Business
- $55–190
- Business Plus
- $70–210
- Economy
- $14–75
- Economy Plus
- $15–85
Train from Buffalo to Oakville
- Ave. Duration
- 3h 47m
- Frequency
- Once daily
- Estimated price
- $35–230
- Website
- VIA Rail
- Escape
- $35–110
- Business
- $80–220
- Business Plus
- $95–230
- Economy
- $40–120
- Economy Plus
- $40–130
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Cleveland to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- Once daily
- Estimated price
- $25–80
- Website
- Barons Bus
- Phone
- +1 800-858-8555
- Website
- Trailways
Bus from Buffalo to Mississauga
- Saver
- $28–70
- Flexible
- $55–70
Bus from Niagara Falls to Mississauga
- Saver
- $24–50
- Flexible
- $49–53
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Cleveland Bus Station to Erie
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- $27–45
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Erie to Toronto
- Ave. Duration
- 4h 40m
- Frequency
- 4 times a week
- Estimated price
- $40–65
- Schedules at
- Flixbus USA
Want to know more about travelling around Canada
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Booking & Getting There
Cleveland to Mississauga bus services, operated by Barons Bus, arrive at Buffalo station.
Cleveland to Mississauga train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Cleveland to Mississauga is 442 km. It takes approximately 4h 51m to drive from Cleveland to Mississauga.
Book your Cleveland to Mississauga bus tickets online with Omio.
There are 1741+ hotels available in Mississauga.
















