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How to get fromCleveland to Des Moinesby plane, train, bus, car or bus (Greyhound)

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There are 6 ways to get from Cleveland to Des Moines by plane, train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cleveland-Hopkins International Airport to Des Moines

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM)plane plane CLE - DSM
    5h 13m
    $190–1,124

  2. Bus

    cheapest
    1. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S
    17h 5m
    $95–199

  3. Train, bus

    1. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train Floridian / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0155S
    16h 20m
    $157–328

  4. Drive 657.8 mi

    1. Drive from Cleveland to Des Moinescar car 657.8 mi
    10h 57m
    $120–174

  5. Bus to Akron, fly to Des Moines

    1. Take the bus from Cleveland, OH to Robert K Pfaff Transit Center - Akronbus bus
    2. Fly from Akron (CAK) to Des Moines (DSM)plane plane CAK - DSM
    7h 48m
    $153–782

  6. Fly Cleveland-Hopkins International Airport to Fort Dodge Municipal Airport, drive

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Fort Dodge Municipal Airport (FOD)plane plane CLE - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar car
    7h 24m
    $98–498

Cleveland to Des Moines by train, foot, and bus

Calendar7Weekly Services
Duration16h 20mAverage Duration
Ticket$157Cheapest Price
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Questions & Answers

What companies run services between Cleveland, OH, USA and Des Moines, IA, USA?

Southwest Airlines, Delta, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Cleveland Bus Station to Des Moines via Chicago Bus Station in around 17h 5m.

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