There are 6 ways to get from Cleveland to Des Moines by plane, train, bus, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Cleveland-Hopkins International Airport to Des Moines
best- Fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM)plane CLE - DSM
5h 13m$190–974Bus
cheapest- Take the bus from Cleveland to Chicagobus Cleveland
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
15h 5m$86–191Train, bus
- Take the train from Cleveland Amtrak to Chicago Union Stationtrain Floridian / ...
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
14h 25m$142–310Drive 657.8 mi
- Drive from Cleveland to Des Moinescar 657.8 mi
10h 57m$120–174Bus to Akron, fly to Des Moines
- Take the bus from Cleveland, OH to Robert K Pfaff Transit Center - Akronbus
- Fly from Akron (CAK) to Des Moines (DSM)plane CAK - DSM
7h 39m$130–705Fly Cleveland-Hopkins International Airport to Fort Dodge Municipal Airport, drive
- Fly from Cleveland-Hopkins International Airport (CLE) to Fort Dodge Municipal Airport (FOD)plane CLE - FOD
- Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar
7h 23m$104–508
Cleveland to Des Moines by train, foot, and bus
Questions & Answers
The cheapest way to get from Cleveland to Des Moines is to bus which costs $85 - $200 and takes 15h 5m.
The fastest way to get from Cleveland to Des Moines is to fly which takes 5h 13m and costs $190 - $1,000.
No, there is no direct bus from Cleveland to Des Moines. However, there are services departing from Cleveland and arriving at Des Moines via Chicago Bus Station. The journey, including transfers, takes approximately 15h 5m.
The distance between Cleveland and Des Moines is 633 miles. The road distance is 661.6 miles.
The best way to get from Cleveland to Des Moines without a car is to train and bus which takes 14h 25m and costs $140 - $310.
It takes approximately 5h 13m to get from Cleveland to Des Moines, including transfers.
Cleveland to Des Moines bus services, operated by Barons Bus, depart from Cleveland station.
The best way to get from Cleveland to Des Moines is to fly which takes 5h 13m and costs $190 - $1,000. Alternatively, you can bus, which costs $85 - $200 and takes 15h 5m.
Cleveland to Des Moines bus services, operated by Barons Bus, arrive at Chicago station.
Des Moines is 1h behind Cleveland. It is currently 2:10 PM in Cleveland and 1:10 PM in Des Moines.
What companies run services between Cleveland, OH, USA and Des Moines, IA, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Cleveland to Des Moines via Chicago Bus Station in around 15h 5m.
- Website
- united.com
Flights from Cleveland-Hopkins International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $170–950
Flights from Akron to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $110–650
Flights from Cleveland-Hopkins International Airport to Fort Dodge Municipal Airport via Chicago O'Hare
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $85–480
- Website
- aa.com
Flights from Cleveland-Hopkins International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $170–950
Flights from Cleveland-Hopkins International Airport to Des Moines via Reagan Washington
- Ave. Duration
- 5h 32m
- When
- Sunday and Saturday
- Estimated price
- $270–1,300
Flights from Cleveland-Hopkins International Airport to Des Moines via Charlotte
- Ave. Duration
- 5h 41m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $280–1,300
Flights from Akron to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $110–650
Flights from Akron to Des Moines via Charlotte
- Ave. Duration
- 5h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $180–850
- Website
- delta.com
Flights from Cleveland-Hopkins International Airport to Des Moines via Detroit
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Cleveland-Hopkins International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $290–1,400
Flights from Cleveland-Hopkins International Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $210–1,100
- Website
- allegiantair.com
Flights from Akron to Des Moines via St. Petersburg
- Ave. Duration
- 6h 33m
- When
- Monday and Friday
- Estimated price
- $270–1,200
Flights from Akron to Des Moines via Jacksonville
- Ave. Duration
- 7h 18m
- When
- Thursday
- Estimated price
- $240–1,100
- Website
- southwest.com
Flights from Cleveland-Hopkins International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 3h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $170–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Cleveland Amtrak to Chicago Union Station
- Ave. Duration
- 6h 46m
- Frequency
- 3 times a day
- Estimated price
- $90–200
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Cleveland to Chicago
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $35–85
- Website
- https://baronsbus.com
Bus from Cleveland, OH to Robert K Pfaff Transit Center - Akron
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $3–35
- Website
- https://baronsbus.com
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Cleveland, OH to Robert K Pfaff Transit Center - Akron
- Ave. Duration
- 50 min
- Frequency
- Twice daily
- Estimated price
- $15–25
- Website
- https://ridewithmiller.com
- Phone
- +1 888 954 6287
- gobus@hapcap.org
- Website
- ridegobus.com
Bus from Cleveland, OH to Robert K Pfaff Transit Center - Akron
- Ave. Duration
- 55 min
- Frequency
- Twice daily
- Estimated price
- $8–11
- Website
- https://ridegobus.com
- Book at
- https://booking.ridegobus.com
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More Questions & Answers
Yes, the driving distance between Cleveland to Des Moines is 662 miles. It takes approximately 10h 57m to drive from Cleveland to Des Moines.
Book your Cleveland to Des Moines bus tickets online with Omio.
There are 512+ hotels available in Des Moines.














