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How to get fromCleveland to Des Moinesby plane, train, bus, car or bus (Greyhound)

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There are 8 ways to get from Cleveland to Des Moines by plane, train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cleveland-Hopkins International Airport to Des Moines

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM)planeCLE - DSM
    5h 33m
    $170–874

  2. Bus

    cheapest
    1. Take the bus from Cleveland Bus Station to Chicago Bus StationbusGreyhound US0164
    2. Take the bus from Chicago to Des MoinesbusChicago
    15h 35m
    $90–246

  3. Train, bus

    1. Take the train from Cleveland Amtrak to Chicago Union StationtrainFloridian / ...
    2. Take the bus from Chicago to Des MoinesbusChicago
    15h 5m
    $107–299

  4. Train, bus via Galesburg

    1. Take the train from Cleveland Amtrak to Chicago Union Stationtrain
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
    3. Take the bus from Galesburg to Burlingtonbus
    4. Take the bus from Burlington to Des Moinesbus
    16h 37m
    $147–354

  5. Drive 657.8 mi

    1. Drive from Cleveland to Des Moinescar657.8 mi
    10h 50m
    $120–174

  6. Bus to Akron, fly to Des Moines

    1. Take the bus from Cleveland, OH to Akron, OHbus
    2. Fly from Akron (CAK) to Des Moines (DSM)planeCAK - DSM
    8h 9m
    $140–755

  7. Fly Cleveland-Hopkins International Airport to Fort Dodge Municipal Airport, drive

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Fort Dodge Municipal Airport (FOD)planeCLE - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar
    7h 28m
    $98–488

  8. Bus via Shipshewana

    1. Take the bus from Cleveland to Shipshewanabus
    2. Take the bus from Shipshewana to Chicagobus
    3. Take the bus from Chicago to Des Moinesbus
    16h 45m
    $91–271

Cleveland to Des Moines by train, foot, and bus

Calendar14Weekly Services
Duration15h 5mAverage Duration
Ticket$107Cheapest Price
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Questions & Answers

What companies run services between Cleveland, OH, USA and Des Moines, IA, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Cleveland Bus Station to Des Moines via Chicago in around 15h 35m.

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