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How to get fromCleveland to Des Moinesby plane, train, bus, bus (Greyhound) or car

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There are 7 ways to get from Cleveland to Des Moines by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Cleveland-Hopkins International Airport to Des Moines

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM)plane plane CLE - DSM
    6h 9m
    $180–924
  2. Bus

    cheapest
    1. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    14h 59m
    $80–175
  3. Train, bus

    1. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train Floridian / ...
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    14h 29m
    $91–233
  4. Drive 657.8 mi

    1. Drive from Cleveland to Des Moinescar car 657.8 mi
    10h 57m
    $120–174
  5. Bus to Akron, fly to Des Moines

    1. Take the bus from Cleveland, OH to Akron, OHbus bus
    2. Fly from Akron (CAK) to Des Moines (DSM)plane plane CAK - DSM
    8h 6m
    $150–805
  6. Fly Cleveland-Hopkins International Airport to Fort Dodge Municipal Airport, drive

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Fort Dodge Municipal Airport (FOD)plane plane CLE - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Des Moinescar car
    8h 1m
    $104–488
  7. Bus via Shipshewana

    1. Take the bus from Cleveland to Shipshewanabus bus
    2. Take the bus from Shipshewana to Chicagobus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    16h 9m
    $81–206

Cleveland to Des Moines by train, foot, and bus

Calendar19Weekly Services
Duration14h 29mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

What companies run services between Cleveland, OH, USA and Des Moines, IA, USA?

United Airlines, American Airlines, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Cleveland Bus Station to Des Moines via Chicago Bus Station in around 14h 59m.

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