There are 8 ways to get from Clemson to Buffalo by taxi, plane, train, bus, train (Amtrak), car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Greenville–Spartanburg International Airport, fly
best- Take the taxi from Clemson to Greenville–Spartanburg International Airport (GSP)
- Fly from Greenville–Spartanburg International Airport (GSP) to Buffalo Niagara International Airport (BUF)GSP - BUF
6h$353–1,609Bus
cheapest- Take the bus from Anderson, SC to New YorkAtlanta
- Take the bus from New York Midtown to BuffaloFlixBus N2686 / ...
24h 59m$113–289Train, bus
- Take the train from Clemson Amtrak Station to Charlotte Amtrak Station
- Take the bus from Charlotte Bus Station to Columbus
- Take the bus from Columbus - Mound St to Buffalo, NY
23h 25m$124–454Train (Amtrak)
- Take the train from Clemson Amtrak Station to Ny Moynihan Train Hall At Penn StationCrescent
- Take the train from Ny Moynihan Train Hall At Penn Station to BuffaloEmpire Service / ...
26h 46m$228–789Drive 753.6 mi
- Drive from Clemson to Buffalo753.6 mi
13h 27m$138–199Drive to Asheville Regional Airport, fly
- Drive from Clemson to Asheville-Airport-AVL
- Fly from Asheville Regional Airport (AVL) to Buffalo Niagara International Airport (BUF)AVL - BUF
6h 43m$207–1,199Train to Charlotte Douglas International Airport, fly
- Take the train from Clemson Amtrak Station to Charlotte Amtrak Station
- Fly from Charlotte Douglas International Airport (CLT) to Buffalo Niagara International Airport (BUF)CLT - BUF
8h 26m$221–1,197Bus to Hartsfield-Jackson Atlanta International Airport, fly
- Take the bus from Anderson, SC to Atlanta
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Buffalo Niagara International Airport (BUF)ATL - BUF
7h 18m$265–1,177
Clemson to Buffalo by train, foot, tram, and bus
Questions & Answers
The cheapest way to get from Clemson to Buffalo is to drive which costs $130 - $200 and takes 13h 27m.
The fastest way to get from Clemson to Buffalo is to taxi and fly which takes 6h and costs $350 - $1,700.
No, there is no direct train from Clemson station to Buffalo. However, there are services departing from Clemson Amtrak Station and arriving at Buffalo via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 26h 46m.
The distance between Clemson and Buffalo is 643 miles. The road distance is 758 miles.
The best way to get from Clemson to Buffalo without a car is to train and bus which takes 23h 25m and costs $120 - $460.
It takes approximately 6h to get from Clemson to Buffalo, including transfers.
Clemson to Buffalo train services, operated by Amtrak, depart from Clemson Amtrak Station.
The best way to get from Clemson to Buffalo is to train which takes 26h 46m and costs $220 - $800. Alternatively, you can bus, which costs $110 - $290 and takes 24h 59m.
Clemson to Buffalo train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Clemson to Buffalo is 758 miles. It takes approximately 13h 27m to drive from Clemson to Buffalo.
What companies run services between Clemson, SC, USA and Buffalo, NY, USA?
You can take a train from Clemson Amtrak Station to Buffalo via Ny Moynihan Train Hall At Penn Station in around 26h 46m. Alternatively, you can take a vehicle from Clemson to Buffalo via Anderson, SC, New York, Canal St, 34 St-Herald Sq, and New York Midtown in around 24h 59m.
- Website
- aa.com
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $240–1,400
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 4h 52m
- When
- Every day
- Estimated price
- $280–1,500
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 5h 49m
- When
- Thursday and Saturday
- Estimated price
- $260–1,400
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $190–1,100
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 5h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,200
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 6h 46m
- When
- Saturday and Sunday
- Estimated price
- $230–1,200
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 7h 12m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $200–1,100
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 3h 47m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $180–1,000
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 6m
- When
- Saturday
- Estimated price
- $210–1,100
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 9m
- When
- Thursday
- Estimated price
- $190–1,100
- Website
- delta.com
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 5h 1m
- When
- Every day
- Estimated price
- $300–1,500
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $270–1,500
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 4h 57m
- When
- Every day
- Estimated price
- $230–1,200
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 7h 18m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $230–1,200
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $200–1,100
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 59m
- When
- Every day
- Estimated price
- $190–1,000
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $200–1,100
- Website
- southwest.com
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $260–1,400
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 4h 47m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $300–1,600
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 2m
- When
- Wednesday and Thursday
- Estimated price
- $210–1,100
- Website
- united.com
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $250–1,400
Flights from Charlotte Douglas International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 3h 51m
- When
- Friday and Saturday
- Estimated price
- $180–1,000
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $200–1,100
- Website
- flyfrontier.com
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 2h 4m
- When
- Monday, Wednesday, Friday, and Saturday
- Estimated price
- $190–1,000
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Clemson Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $40–120
- Website
- https://www.amtrak.com/home.html
Train from Clemson Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 17h 1m
- Frequency
- Once daily
- Estimated price
- $150–650
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Buffalo
- Ave. Duration
- 8h 45m
- Frequency
- 3 times a day
- Estimated price
- $75–160
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Charlotte Bus Station to Columbus
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $65–260
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Charlotte Bus Station to Columbus
- Ave. Duration
- 10h 45m
- Frequency
- Once daily
- Estimated price
- $45–100
- Website
- https://baronsbus.com
Bus from Columbus - Mound St to Buffalo, NY
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- https://baronsbus.com
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Anderson, SC to Atlanta
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
Bus from Anderson, SC to New York
- Ave. Duration
- 15h
- Frequency
- 3 times a day
- Estimated price
- $30–140
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 16m
- Frequency
- Every 4 hours
- Estimated price
- $50–110
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Book your Clemson to Buffalo train tickets online with Omio.
There are 231+ hotels available in Buffalo.













