There are 7 ways to get from Clemson to Buffalo by taxi, plane, train, bus, bus (Flixbus), car, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Greenville–Spartanburg International Airport, fly
best- Take the taxi from Clemson to Greenville–Spartanburg International Airport (GSP)taxi
- Fly from Greenville–Spartanburg International Airport (GSP) to Buffalo Niagara International Airport (BUF)plane GSP - BUF
6h$355–1,611Bus
cheapest- Take the bus from Anderson, SC to New Yorkbus Atlanta
- Take the bus from New York Midtown to Buffalobus FlixBus 2686 / ...
25h 8m$113–279Train, bus
- Take the train from Clemson Amtrak Station to Newark Penn Stationtrain Crescent
- Take the bus from Newark to Buffalobus Adt N816 / ...
25h 6m$211–868Drive 750.2 mi
- Drive from Clemson to Buffalocar 750.2 mi
13h 42m$137–198Drive to Asheville Regional Airport, fly
- Drive from Clemson to Asheville-Airport-AVLcar
- Fly from Asheville Regional Airport (AVL) to Buffalo Niagara International Airport (BUF)plane AVL - BUF
6h 41m$197–1,199Bus to Hartsfield-Jackson Atlanta International Airport, fly
- Take the bus from Anderson, SC to Atlantabus
- Fly from Hartsfield-Jackson Atlanta International Airport (ATL) to Buffalo Niagara International Airport (BUF)plane ATL - BUF
7h 18m$255–1,177Train (Amtrak)
- Take the train from Clemson Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain Crescent
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain Empire Service / ...
26h 46m$216–611
Clemson to Buffalo by train and bus
Questions & Answers
The cheapest way to get from Clemson to Buffalo is to drive which costs $130 - $200 and takes 13h 42m.
The fastest way to get from Clemson to Buffalo is to taxi and fly which takes 6h and costs $350 - $1,700.
No, there is no direct train from Clemson station to Buffalo. However, there are services departing from Clemson Amtrak Station and arriving at Buffalo via Ny Moynihan Train Hall At Penn Station. The journey, including transfers, takes approximately 26h 46m.
The distance between Clemson and Buffalo is 643 miles. The road distance is 754.6 miles.
The best way to get from Clemson to Buffalo without a car is to train and bus which takes 25h 6m and costs $210 - $900.
It takes approximately 6h to get from Clemson to Buffalo, including transfers.
Clemson to Buffalo train services, operated by Amtrak, depart from Clemson Amtrak Station.
The best way to get from Clemson to Buffalo is to bus which takes 25h 8m and costs $110 - $280. Alternatively, you can train, which costs $210 - $650 and takes 26h 46m.
Clemson to Buffalo train services, operated by Amtrak, arrive at Ny Moynihan Train Hall At Penn Station.
Yes, the driving distance between Clemson to Buffalo is 755 miles. It takes approximately 13h 42m to drive from Clemson to Buffalo.
What companies run services between Clemson, SC, USA and Buffalo, NY, USA?
You can take a vehicle from Clemson to Buffalo via Anderson, SC, New York, Canal St, 34 St-Herald Sq, and New York Midtown in around 25h 8m. Alternatively, you can take a train from Clemson Amtrak Station to Buffalo via Ny Moynihan Train Hall At Penn Station in around 26h 46m.
- Website
- aa.com
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $240–1,400
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $260–1,500
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $280–1,500
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $180–1,100
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 6h 22m
- When
- Sunday
- Estimated price
- $230–1,200
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 6h 38m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $210–1,200
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 6h 58m
- When
- Friday and Saturday
- Estimated price
- $190–1,100
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 4h 6m
- When
- Friday
- Estimated price
- $200–1,100
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $190–1,100
- Website
- delta.com
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 22m
- When
- Monday to Saturday
- Estimated price
- $270–1,500
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $290–1,600
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 6h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $230–1,200
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $200–1,100
- Website
- southwest.com
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $260–1,500
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 4h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $300–1,600
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $200–1,100
- Website
- united.com
Flights from Greenville–Spartanburg International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $250–1,400
Flights from Asheville Regional Airport to Buffalo Niagara International Airport via Newark
- Ave. Duration
- 8h 3m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $190–1,100
- Website
- flyfrontier.com
Flights from Hartsfield-Jackson Atlanta International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 2h 4m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $180–1,000
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Clemson Amtrak Station to Newark Penn Station
- Ave. Duration
- 16h 36m
- Frequency
- Once daily
- Estimated price
- $150–800
- Website
- https://www.amtrak.com/home.html
Train from Clemson Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 17h 1m
- Frequency
- Once daily
- Estimated price
- $150–460
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Buffalo
- Ave. Duration
- 8h 45m
- Frequency
- 3 times a day
- Estimated price
- $65–160
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Newark to Buffalo
- Ave. Duration
- 7h 30m
- Frequency
- Twice daily
- Estimated price
- $55–90
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Anderson, SC to New York
- Ave. Duration
- 15h
- Frequency
- 3 times a day
- Estimated price
- $30–140
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
Bus from Anderson, SC to Atlanta
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from New York Midtown to Buffalo
- Ave. Duration
- 8h 25m
- Frequency
- Every 3 hours
- Estimated price
- $50–100
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your Clemson to Buffalo train tickets online with Omio.
There are 219+ hotels available in Buffalo.








