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There are 4 ways to get from Cincinnati to Great Smoky Mountains by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, drive  •  19 h 33 min

  1. Take the bus from University of Cincinnati, OH to Columbus, OH
  2. Take the bus from Columbus, Oh to Winston Salem, Nc
  3. Take the bus from Winston Salem, Nc to Asheville, Nc
  4. Drive from Asheville, Nc to Great Smoky Mountains

$83 - $200

Cheapest option

Fly Cincinnati to Atlanta De Kalb Peachtree, drive  •  5 h 59 min

  1. Fly from Cincinnati (LUK) to Atlanta De Kalb Peachtree (PDK) LUK - PDK
  2. Drive from Atlanta De Kalb Peachtree to Great Smoky Mountains

$54 - $288

2 alternative options

Drive  •  5 h 56 min

  1. Drive from Cincinnati to Great Smoky Mountains 320.4 miles

$30 - $50

Fly Covington to Knoxville, drive  •  7 h 3 min

  1. Fly from Covington (CVG) to Knoxville (TYS) CVG - TYS
  2. Drive from Knoxville to Great Smoky Mountains

$208 - $1,112

Questions & Answers

The cheapest way to get from Cincinnati to Great Smoky Mountains is to drive which costs $30 - $50 and takes 5 h 56 min.

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The quickest way to get from Cincinnati to Great Smoky Mountains is to drive which costs $30 - $50 and takes 5 h 56 min.

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The distance between Cincinnati and Great Smoky Mountains is 252 miles. The road distance is 320.4 miles.

Get driving directions

It takes approximately 19 h 33 min to get from Cincinnati to Great Smoky Mountains, including transfers.

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There is no direct flight from Covington Airport to Knoxville Airport. The quickest flight takes 3 h 35 min and has one stopover.

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Yes, the driving distance between Cincinnati to Great Smoky Mountains is 320 miles. It takes approximately 5 h 56 min to drive from Cincinnati to Great Smoky Mountains.

Get driving directions

United Airlines, American Airlines and Delta offer flights from Covington Airport to Knoxville Airport.

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There are 1383+ hotels available in Great Smoky Mountains. Prices start at $62 USD per night.

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The best way to get from Cincinnati to Covington Airport is to bus which takes 21 min and costs $2.

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Map of how to get from Cincinnati to Great Smoky Mountains.
Launch map view
  • Distance: 252.5 miles
  • Duration: 19 h 33 min

What companies run services between Cincinnati, OH, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Cincinnati to Great Smoky Mountains. However, you can take the bus to Columbus, OH, take the walk to Columbus, Oh, take the bus to Winston Salem, Nc, take the bus to Asheville, Nc, then take the drive to Great Smoky Mountains. Alternatively, you can take the drive to Great Smoky Mountains.

Airlines
Delta
Website
delta.com
Flights from Covington to Knoxville via Atlanta
Ave. Duration
4 h 27 min
When
Every day
Estimated price
$200 - $1,100
Flights from Covington to Knoxville via Detroit
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$210 - $1,100
Flights from Covington to Knoxville via New York La Guardia
Ave. Duration
5 h 11 min
When
Monday, Thursday, Friday and Sunday
Estimated price
$260 - $1,200
American Airlines
Website
aa.com
Flights from Covington to Knoxville via Charlotte
Ave. Duration
4 h 32 min
When
Every day
Estimated price
$210 - $1,100
Flights from Covington to Knoxville via Chicago O'Hare
Ave. Duration
4 h 45 min
When
Every day
Estimated price
$230 - $1,100
Flights from Covington to Knoxville via Reagan Washington
Ave. Duration
4 h 37 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,200
United Airlines
Website
united.com
Flights from Covington to Knoxville via Chicago O'Hare
Ave. Duration
4 h 1 min
When
Every day
Estimated price
$250 - $1,200
Flights from Covington to Knoxville via Washington Dulles
Ave. Duration
4 h
When
Every day
Estimated price
$250 - $1,200
Regional Sky
Website
regionalsky.com
Flights from Cincinnati to Atlanta De Kalb Peachtree
Ave. Duration
1 h 5 min
When
Monday to Friday
Estimated price
$35 - $260
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbus, Oh to Winston Salem, Nc
Ave. Duration
10 h 35 min
Frequency
3 times a day
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Once daily
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50

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