Rome2Rio

How to get fromCincinnati Union Terminal to St. Louisby train, bus, train (Amtrak), car, plane or bus (Flixbus, Greyhound)

Find Transport to St. Louis

See all options

There are 7 ways to get from Cincinnati Union Terminal to St. Louis by train, bus, train (Amtrak), car, plane, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Cincinnati Union Terminal to IndianapolistrainCardinal
    2. Take the bus from Indianapolis Union Station to St Louis Bus StationbusGreyhound US0421
    8h 29m
    $70–120

  2. Bus

    cheapest
    1. Take the bus from Cincinnati to IndianapolisbusFlixBus 2514
    2. Take the bus from Indianapolis Union Station to St Louis Bus StationbusGreyhound US0421
    9h 4m
    $52–162

  3. Train (Amtrak)

    1. Take the train from Cincinnati Union Terminal to Chicago Union StationtrainCardinal
    2. Take the train from Chicago Union Station to St. LouistrainLincoln Service / ...
    15h 5m
    $117–370

  4. Drive 346.7 mi

    1. Drive from Cincinnati Union Terminal to St. Louiscar346.7 mi
    5h 45m
    $64–92

  5. Drive to Louisville International Airport, fly

    1. Drive from Cincinnati Union Terminal to Louisville International Airport (SDF)car
    2. Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)planeSDF - STL
    5h 29m
    $322–581

  6. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)planeCVG - STL
    6h 14m
    $127–757

  7. Bus to John Glenn Columbus International Airport, fly

    1. Take the bus from Cincinnati - Downtown to Columbus - Downtown - Mound Stbus
    2. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)planeCMH - STL
    7h 3m
    $265–678

Cincinnati Union Terminal to St. Louis by train and bus

Calendar3Weekly Services
Duration8h 29mAverage Duration
Ticket$70Cheapest Price
See schedules

Questions & Answers

What companies run services between Cincinnati Union Terminal, OH, USA and St. Louis, MO, USA?

You can take a train from Cincinnati Union Terminal to St. Louis via Chicago Union Station in around 15h 5m. Alternatively, you can take a vehicle from Cincinnati Union Terminal to St Louis Bus Station via Vine St & Clifton Ave, Vine St & Martin Luther King Dr, Cincinnati, Indianapolis, and Indianapolis Union Station in around 9h 4m.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Cincinnati Union Terminal

Trips to St. Louis

Popular routes