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How to get fromChicago to Waterlooby train (Amtrak), bus (Flixbus), car, plane or train

Find Transport to Waterloo

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There are 8 ways to get from Chicago to Waterloo by train (Amtrak), bus (Flixbus), car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    5h 20m
    $118–213

  2. Drive 315 mi

    cheapest
    1. Drive from Chicago to Waterloocar car 315 mi
    5h 21m
    $58–83

  3. Bus (Flixbus)

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus N2521 / ...
    6h 44m
    $93–134

  4. Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    2. Take the train from LAMBERT AIRPORT TERMINAL #1 station to MEMORIAL HOSPITAL stationtrain train
    4h 47m
    $306–668

  5. Fly Chicago Midway International Airport to Lambert–St. Louis International Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    2. Take the train from LAMBERT AIRPORT TERMINAL #1 station to MEMORIAL HOSPITAL stationtrain train
    4h 28m
    $166–868

  6. Train to General Mitchell International Airport, fly to Lambert–St. Louis International Airport, train

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    3. Take the train from LAMBERT AIRPORT TERMINAL #1 station to MEMORIAL HOSPITAL stationtrain train
    6h 9m
    $214–1,120

  7. Fly Chicago O'Hare International Airport to Decatur Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Decatur Airport (DEC)plane plane ORD - DEC
    2. Drive from Decatur Airport (DEC) to Waterloocar car
    5h 45m
    $58–285

  8. Fly Chicago O'Hare International Airport to Abraham Lincoln Capital Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Abraham Lincoln Capital Airport (SPI)plane plane ORD - SPI
    2. Take the train from Springfield to St. Louistrain train
    6h 21m
    $122–381

Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL) flights

Calendar126Weekly Planes
Duration1h 25mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Waterloo, IL, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $60–150 and the journey takes 4h 46m. Alternatively, Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station 3 times a day. Tickets cost $35–65 and the journey takes 6h 10m.

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