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How to get fromChicago to Simpsonvilleby plane, bus (Greyhound, Flixbus), train, bus, taxi, car or bus (Greyhound)

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There are 8 ways to get from Chicago to Simpsonville by plane, bus (Greyhound, Flixbus), train, bus, taxi, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    4h 5m
    $112–500

  2. Fly Chicago O'Hare International Airport to Asheville Regional Airport, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Drive from Asheville-Airport-AVL to Simpsonvillecar car
    4h 51m
    $64–332

  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    21h 32m
    $181–426

  4. Train, bus, taxi

    1. Take the train from Chicago Union Station to Carytrain train
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte to Servicios Zapata - Spartanburgbus bus
    4. Take the taxi from Servicios Zapata - Spartanburg to Simpsonvilletaxi taxi
    32h 9m
    $452–963

  5. Drive 680.6 mi

    1. Drive from Chicago to Simpsonvillecar car 680.6 mi
    13h
    $125–180

  6. Fly Chicago Midway International Airport to Greenville–Spartanburg International Airport

    1. Fly from Chicago Midway International Airport (MDW) to Greenville–Spartanburg International Airport (GSP)plane plane MDW - GSP
    5h 42m
    $158–750

  7. Fly Chicago O'Hare International Airport to Columbia, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Columbia (CAE)plane plane ORD - CAE
    2. Drive from Columbia-Airport-CAE to Simpsonvillecar car
    5h 21m
    $78–370

  8. Bus via 510 & 601 Connection

    1. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    22h 32m
    $194–410

Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) flights

Calendar92Weekly Planes
Duration2h 59mAverage Duration
Ticket$78Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Simpsonville, SC, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Chicago Bus Station to Simpsonville via Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 21h 32m.

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