There are 6 ways to get from Chicago to Sikeston by plane, taxi, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Cape Girardeau Municipal Airport, taxi
best- Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane ORD - CGI
- Take the taxi from Cape Girardeau Municipal Airport (CGI) to Sikestontaxi
3h 55m$132–260Drive 395 mi
cheapest- Drive from Chicago to Sikestoncar 395 mi
6h 31m$73–105Train, taxi (Amtrak)
- Take the train from Chicago Union Station to Fulton Amtrak Stationtrain City of New Orleans
- Take the taxi from Fulton Amtrak Station to Sikestontaxi
8h 38m$208–365Bus
- Take the bus from Tornado Bus Co - Chicago to Flying J - Matthewsbus Milwaukee
9h 16m$100–221Fly to Barkley Regional Airport, taxi
- Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane ORD - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Sikestontaxi
4h 26m$312–1,755Fly to Williamson County Regional Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane ORD - MWA
- Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus
6h 6m$134–355
Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights
Questions & Answers
The cheapest way to get from Chicago to Sikeston is to drive which costs $70 - $110 and takes 6h 31m.
The fastest way to get from Chicago to Sikeston is to fly and taxi which takes 3h 55m and costs $130 - $260.
The distance between Chicago and Sikeston is 389 miles. The road distance is 397.3 miles.
The best way to get from Chicago to Sikeston without a car is to train and taxi which takes 8h 38m and costs $200 - $370.
It takes approximately 3h 55m to get from Chicago to Sikeston, including transfers.
Yes, the driving distance between Chicago to Sikeston is 397 miles. It takes approximately 6h 31m to drive from Chicago to Sikeston.
There are 13+ hotels available in Sikeston.
What companies run services between Chicago, IL, USA and Sikeston, MO, USA?
Tornado Bus Company operates a bus from Tornado Bus Co - Chicago to Flying J - Matthews once daily. Tickets cost $75–190 and the journey takes 7h 24m.
- Website
- contouraviation.com
Flights from Chicago O'Hare International Airport to Cape Girardeau Municipal Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $60–170
Flights from Chicago O'Hare International Airport to Williamson County Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $60–170
- Website
- united.com
Flights from Chicago O'Hare International Airport to Barkley Regional Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $70–480
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Fulton Amtrak Station
- Ave. Duration
- 7h 7m
- Frequency
- Once daily
- Estimated price
- $65–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Tornado Bus Co - Chicago to Flying J - Matthews
- Ave. Duration
- 7h 24m
- Frequency
- Once daily
- Estimated price
- $75–190
- Schedules at
- tornadobus.com
- Adults 11-59
- $75–190
Bus from Marathon Gas Station - Marion to Flying J - Matthews
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
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