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How to get fromChicago to Santeeby plane, train (Amtrak), bus, taxi, car or train

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There are 7 ways to get from Chicago to Santee by plane, train (Amtrak), bus, taxi, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to San Diego International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN)plane plane MDW - SAN
    7h 34m
    $286–1,335

  2. Fly Chicago O'Hare International Airport to Los Angeles International Airport, bus

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Los Angeles International Airport (LAX)plane plane ORD - LAX
    2. Take the bus from LAX Terminal 3 Shared Rides Stop to San Diegobus bus
    10h 58m
    $156–575

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2. Take the train from Fullerton Amtrak Station to San Diego Old Town Transportation Centertrain train Pacific Surfliner
    47h 2m
    $522–1,206

  4. Bus, taxi

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus
    3. Take the bus from Los Angeles Union Station to San Ysidrobus bus
    4. Take the taxi from San Ysidro to Santeetaxi taxi
    2d 2h
    $458–818

  5. Drive 2,074.7 mi

    1. Drive from Chicago to Santeecar car 2,074.7 mi
    32h 34m
    $379–547

  6. Fly Chicago O'Hare International Airport to San Diego International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to San Diego International Airport (SAN)plane plane ORD - SAN
    7h 57m
    $186–885

  7. Train to General Mitchell International Airport, fly to San Diego International Airport

    1. Take the train from Chicago Union Station to Milwaukeetrain train
    2. Fly from General Mitchell International Airport (MKE) to San Diego International Airport (SAN)plane plane MKE - SAN
    9h 11m
    $355–1,587

Chicago to Santee by train and tram (Amtrak)

Calendar13Weekly Services
Duration47h 2mAverage Duration
Ticket$522Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Santee, CA, USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a train from Chicago Union Station to Santee Town Center Station via Fullerton Amtrak Station, San Diego Old Town Transportation Center, Old Town Station, and El Cajon Station in around 47h 2m.

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