There are 9 ways to get from Chicago to Prairie du Chien by plane, car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to La Crosse, drive
best- Fly from Chicago O'Hare International Airport (ORD) to La Crosse (LSE)plane ORD - LSE
- Drive from La-Crosse-Airport-LSE to Prairie du Chiencar
4h 25m$48–283Drive 225.9 mi
cheapest- Drive from Chicago to Prairie du Chiencar 225.9 mi
4h 44m$42–60Train, bus, drive
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to UW La Crossebus
- Drive from UW La Crosse to Prairie du Chiencar
7h 22m$51–147Fly to Dane County Regional Airport-Truax Field, drive
- Fly from Chicago O'Hare International Airport (ORD) to Dane County Regional Airport-Truax Field (MSN)plane ORD - MSN
- Drive from Madison-Airport-MSN to Prairie du Chiencar
5h 5m$72–463Fly to The Eastern Iowa Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to The Eastern Iowa Airport (CID)plane ORD - CID
- Drive from Cedar-Rapids-Airport-CID to Prairie du Chiencar
5h 12m$52–283Fly to Waterloo Municipal Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Waterloo Municipal Airport (ALO)plane ORD - ALO
- Drive from Waterloo Municipal Airport (ALO) to Prairie du Chiencar
5h 7m$54–290Fly to Quad City International Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane ORD - MLI
- Drive from Moline-Airport-MLI to Prairie du Chiencar
5h 46m$58–285Bus, drive
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to La Crossebus
- Drive from La Crosse to Prairie du Chiencar
8h 26m$45–132Bus, drive #2
- Take the bus from Chicago Bus Station to Madisonbus
- Take the bus from Madison to La Crossebus
- Drive from La Crosse to Prairie du Chiencar
8h 26m$50–131
Chicago O'Hare International Airport (ORD) to La Crosse (LSE) flights
Questions & Answers
The cheapest way to get from Chicago to Prairie du Chien is to drive which costs $40 - $60 and takes 4h 44m.
The fastest way to get from Chicago to Prairie du Chien is to fly and drive which takes 4h 25m and costs $45 - $290.
The distance between Chicago and Prairie du Chien is 299 miles. The road distance is 227.2 miles.
It takes approximately 4h 25m to get from Chicago to Prairie du Chien, including transfers.
Yes, the driving distance between Chicago to Prairie du Chien is 227 miles. It takes approximately 4h 44m to drive from Chicago to Prairie du Chien.
There are 18+ hotels available in Prairie du Chien.
What companies run services between Chicago, IL, USA and Prairie du Chien, WI, USA?
There is no direct connection from Chicago to Prairie du Chien. However, you can take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to La Crosse (LSE), then drive to Prairie du Chien. Alternatively, you can take a train from Chicago Union Station to Prairie du Chien via Milwaukee, Milwaukee, and UW La Crosse in around 7h 22m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to La Crosse
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $35–260
Flights from Chicago O'Hare International Airport to Dane County Regional Airport-Truax Field
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- $50–430
Flights from Chicago O'Hare International Airport to The Eastern Iowa Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $30–250
Flights from Chicago O'Hare International Airport to Waterloo Municipal Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $35–260
Flights from Chicago O'Hare International Airport to Quad City International Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $30–240
- Website
- united.com
Flights from Chicago O'Hare International Airport to La Crosse
- Ave. Duration
- 1h 7m
- When
- Every day
- Estimated price
- $35–260
Flights from Chicago O'Hare International Airport to Dane County Regional Airport-Truax Field
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- $50–430
Flights from Chicago O'Hare International Airport to The Eastern Iowa Airport
- Ave. Duration
- 1h 18m
- When
- Every day
- Estimated price
- $30–250
Flights from Chicago O'Hare International Airport to Quad City International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $30–240
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $21–40
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to UW La Crosse
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $20–95
- Book at
- https://www.jeffersonlines.com
Bus from Madison to La Crosse
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $13–75
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 608-752-5407
- vangalder@coachusa.com
- Website
- coachusa.com
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 50m
- Frequency
- Hourly
- Estimated price
- $21–45
- Website
- https://www.coachusa.com/van-galder-bus-company
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Madison
- Ave. Duration
- 3h 50m
- Frequency
- 3 times a day
- Estimated price
- $26–40
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide









