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How to get fromChicago to Port Isabelby plane, bus, train or car

Find Transport to Port Isabel

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There are 8 ways to get from Chicago to Port Isabel by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Brownsville-South Padre Island International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Brownsville-South Padre Island International Airport (BRO)planeORD - BRO
    8h 40m
    $114–557

  2. Bus

    1. Take the bus from Chicago to Dallas JeffersonbusChicago
    2. Take the bus from Dallas to BrownsvillebusDallas
    30h 43m
    $264–442

  3. Train, bus via Dallas

    1. Take the train from Chicago Union Station to DallastrainTexas Eagle
    2. Take the bus from Dallas to BrownsvillebusDallas
    34h 56m
    $233–525

  4. Drive 1,436.9 mi

    1. Drive from Chicago to Port Isabelcar1,436.9 mi
    25h 20m
    $263–379

  5. Fly Chicago O'Hare International Airport to Mcallen Miller International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Mcallen Miller International Airport (MFE)planeORD - MFE
    2. Take the bus from McAllen Central Station to Brownsvillebus
    11h 11m
    $190–719

  6. Fly Chicago Midway International Airport to Rio Grande Valley International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Rio Grande Valley International Airport (HRL)planeMDW - HRL
    2. Take the bus from Harlingen Bus Station to Brownsvillebus
    10h 57m
    $142–559

  7. Fly Chicago O'Hare International Airport to Rio Grande Valley International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Rio Grande Valley International Airport (HRL)planeORD - HRL
    2. Take the bus from Harlingen Bus Station to Brownsvillebus
    10h 13m
    $126–479

  8. Train, bus

    1. Take the train from Chicago Union Station to San Marcos AmtraktrainTexas Eagle
    2. Take the bus from San Marcos to La Plaza at BrownsvillebusFlixBus US1164
    42h 22m
    $188–389

Chicago O'Hare International Airport (ORD) to Brownsville-South Padre Island International Airport (BRO) flights

Calendar69Weekly Planes
Duration6h 31mAverage Duration
Ticket$111Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Port Isabel, TX, USA?

United Airlines and American Airlines fly from Chicago O'Hare International Airport (ORD) to Brownsville-South Padre Island International Airport (BRO) every 3 hours. Alternatively, you can take a vehicle from Chicago to Las Palmas Port Isabel via Chicago, Dallas Jefferson, Dallas, and La Plaza at Brownsville in around 30h 43m.

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