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How to get fromChicago to Pickensby plane, taxi, bus (Flixbus, Greyhound), train, bus, car, bus (Flixbus), or bus (Greyhound, Flixbus)

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There are 8 ways to get from Chicago to Pickens by plane, taxi, bus (Flixbus, Greyhound), train, bus, car, bus (Flixbus), or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Pickenstaxi taxi
    4h 32m
    $188–665

  2. Drive 659.6 mi

    cheapest
    1. Drive from Chicago to Pickenscar car 659.6 mi
    13h 6m
    $121–174

  3. Bus

    1. Take the bus from Chicago to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    20h 53m
    $206–433

  4. Train, bus

    1. Take the train from Chicago Union Station to Carytrain train
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    32h 48m
    $500–1,018

  5. Fly Chicago O'Hare International Airport to Asheville Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Take the taxi from Asheville-Airport-AVL to Pickenstaxi taxi
    4h 52m
    $202–535

  6. Fly Chicago Midway International Airport to Asheville Regional Airport, taxi

    1. Fly from Chicago Midway International Airport (MDW) to Asheville Regional Airport (AVL)plane plane MDW - AVL
    2. Take the taxi from Asheville-Airport-AVL to Pickenstaxi taxi
    6h 34m
    $232–665

  7. Bus via Bloomington

    1. Take the bus from Chicago Bus Station to Bloomingtonbus bus
    2. Take the bus from Bloomington to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus
    21h 24m
    $214–407

  8. Bus #2

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    21h 57m
    $216–427

Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) flights

Calendar91Weekly Planes
Duration2h 49mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Pickens.ExpandLaunch map view
  • Distance: 627.9 mi
  • Duration: 4h 32m

What companies run services between Chicago, IL, USA and Pickens, SC, USA?

You can take a subway from Harrison to Pickens via 95th, Chicago, Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 20h 53m.

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