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How to get fromChicago to Picayuneby plane, taxi, train (Amtrak), bus (Flixbus, Greyhound), car or train

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There are 9 ways to get from Chicago to Picayune by plane, taxi, train (Amtrak), bus (Flixbus, Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Gulfport-Biloxi Regional Airport, taxi

    best
    1. Fly from Chicago Midway International Airport (MDW) to Gulfport-Biloxi Regional Airport (GPT)plane plane MDW - GPT
    2. Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi taxi
    6h 47m
    $222–745

  2. Fly Chicago Midway International Airport to Louis Armstrong New Orleans International Airport, train

    cheapest
    1. Fly from Chicago Midway International Airport (MDW) to Louis Armstrong New Orleans International Airport (MSY)plane plane MDW - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain train
    7h 56m
    $102–485

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train City of New Orleans
    2. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain train Crescent
    22h 2m
    $146–310

  4. Bus

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus N2521 / ...
    2. Take the bus from St Louis Bus Station to Slidellbus bus Greyhound US1173
    23h 32m
    $157–290

  5. Drive 887 mi

    1. Drive from Chicago to Picayunecar car 887 mi
    14h 38m
    $162–234

  6. Fly Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Gulfport-Biloxi Regional Airport (GPT)plane plane ORD - GPT
    2. Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi taxi
    7h 45m
    $198–585

  7. Fly Chicago O'Hare International Airport to Louis Armstrong New Orleans International Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Louis Armstrong New Orleans International Airport (MSY)plane plane ORD - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain train
    8h 20m
    $102–375

  8. Fly Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport, drive

    1. Fly from Chicago Midway International Airport (MDW) to Birmingham–Shuttlesworth International Airport (BHM)plane plane MDW - BHM
    2. Drive from Birmingham-Airport-BHM to Picayunecar car
    8h 10m
    $182–885

  9. Fly Chicago O'Hare International Airport to Birmingham–Shuttlesworth International Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Birmingham–Shuttlesworth International Airport (BHM)plane plane ORD - BHM
    2. Drive from Birmingham-Airport-BHM to Picayunecar car
    8h 40m
    $152–685

Chicago to Picayune by train (Amtrak)

Calendar7Weekly Trains
Duration22h 2mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Picayune, MS, USA?

You can take a train from Chicago Union Station to Picayune Amtrak Station via New Orleans Union Passenger Terminal in around 22h 2m. Alternatively, you can take a bus from Chicago Bus Station to Picayune via St Louis Bus Station and Slidell in around 23h 32m.

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