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How to get fromChicago to Picayuneby plane, taxi, train (Amtrak), bus (Flixbus, Greyhound), car or train

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There are 9 ways to get from Chicago to Picayune by plane, taxi, train (Amtrak), bus (Flixbus, Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport, taxi

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Gulfport-Biloxi Regional Airport (GPT)planeORD - GPT
    2. Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi
    8h
    $208–615

  2. Fly Chicago Midway International Airport to Louis Armstrong New Orleans International Airport, train

    cheapest
    1. Fly from Chicago Midway International Airport (MDW) to Louis Armstrong New Orleans International Airport (MSY)planeMDW - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain
    7h 56m
    $84–467

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to New Orleans Union Passenger TerminaltrainCity of New Orleans
    2. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak StationtrainCrescent
    22h 2m
    $145–374

  4. Bus

    1. Take the bus from Chicago Bus Station to St Louis Bus StationbusFlixBus N2521 / ...
    2. Take the bus from St Louis Bus Station to SlidellbusGreyhound US1173
    23h 32m
    $159–311

  5. Drive 887 mi

    1. Drive from Chicago to Picayunecar887 mi
    14h 28m
    $162–234

  6. Fly Chicago Midway International Airport to Gulfport-Biloxi Regional Airport, taxi

    1. Fly from Chicago Midway International Airport (MDW) to Gulfport-Biloxi Regional Airport (GPT)planeMDW - GPT
    2. Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi
    6h 54m
    $222–745

  7. Fly Chicago O'Hare International Airport to Louis Armstrong New Orleans International Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Louis Armstrong New Orleans International Airport (MSY)planeORD - MSY
    2. Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain
    8h 23m
    $94–377

  8. Fly Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport, drive

    1. Fly from Chicago Midway International Airport (MDW) to Birmingham–Shuttlesworth International Airport (BHM)planeMDW - BHM
    2. Drive from Birmingham-Airport-BHM to Picayunecar
    8h 2m
    $162–735

  9. Fly Chicago O'Hare International Airport to Birmingham–Shuttlesworth International Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Birmingham–Shuttlesworth International Airport (BHM)planeORD - BHM
    2. Drive from Birmingham-Airport-BHM to Picayunecar
    8h 39m
    $148–635

Chicago to Picayune by train (Amtrak)

Calendar7Weekly Trains
Duration22h 2mAverage Duration
Ticket$145Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Picayune, MS, USA?

You can take a train from Chicago Union Station to Picayune Amtrak Station via New Orleans Union Passenger Terminal in around 22h 2m. Alternatively, you can take a bus from Chicago Bus Station to Picayune via St Louis Bus Station and Slidell in around 23h 32m.

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