There are 9 ways to get from Chicago to Picayune by plane, taxi, train (Amtrak), bus (Flixbus, Greyhound), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport, taxi
best- Fly from Chicago O'Hare International Airport (ORD) to Gulfport-Biloxi Regional Airport (GPT)plane ORD - GPT
- Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi
7h 49m$212–645Fly Chicago Midway International Airport to Louis Armstrong New Orleans International Airport, train
cheapest- Fly from Chicago Midway International Airport (MDW) to Louis Armstrong New Orleans International Airport (MSY)plane MDW - MSY
- Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain
7h 25m$152–695Train (Amtrak)
- Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain City of New Orleans
- Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain Crescent
21h 57m$323–636Bus
- Take the bus from Chicago Bus Station to St Louis Bus Stationbus FlixBus 2510 / ...
- Take the bus from St Louis Bus Station to Slidellbus Greyhound US1173
23h 17m$202–338Drive 887 mi
- Drive from Chicago to Picayunecar 887 mi
14h 32m$162–234Fly Chicago Midway International Airport to Gulfport-Biloxi Regional Airport, taxi
- Fly from Chicago Midway International Airport (MDW) to Gulfport-Biloxi Regional Airport (GPT)plane MDW - GPT
- Take the taxi from Gulfport-Biloxi Regional Airport (GPT) to Picayunetaxi
6h 45m$252–845Fly Chicago O'Hare International Airport to Louis Armstrong New Orleans International Airport, train
- Fly from Chicago O'Hare International Airport (ORD) to Louis Armstrong New Orleans International Airport (MSY)plane ORD - MSY
- Take the train from New Orleans Union Passenger Terminal to Picayune Amtrak Stationtrain
7h 51m$182–645Fly Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport, drive
- Fly from Chicago Midway International Airport (MDW) to Birmingham–Shuttlesworth International Airport (BHM)plane MDW - BHM
- Drive from Birmingham-Airport-BHM to Picayunecar
8h 8m$192–885Fly Chicago O'Hare International Airport to Birmingham–Shuttlesworth International Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Birmingham–Shuttlesworth International Airport (BHM)plane ORD - BHM
- Drive from Birmingham-Airport-BHM to Picayunecar
8h 38m$162–685
Chicago to Picayune by train (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Picayune is to drive which costs $160 - $240 and takes 14h 32m.
The fastest way to get from Chicago to Picayune is to fly and taxi which takes 6h 45m and costs $250 - $850.
No, there is no direct bus from Chicago station to Picayune. However, there are services departing from Chicago Bus Station and arriving at Slidell via St Louis Bus Station. The journey, including transfers, takes approximately 23h 17m.
No, there is no direct train from Chicago station to Picayune station. However, there are services departing from Chicago Union Station and arriving at Picayune Amtrak Station via New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 21h 57m.
The distance between Chicago and Picayune is 870 miles. The road distance is 892.2 miles.
The best way to get from Chicago to Picayune without a car is to train which takes 21h 57m and costs $320 - $650.
It takes approximately 7h 49m to get from Chicago to Picayune, including transfers.
Chicago to Picayune bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Picayune train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Picayune is to train which takes 21h 57m and costs $320 - $650. Alternatively, you can bus, which costs $200 - $340 and takes 23h 17m.
What companies run services between Chicago, IL, USA and Picayune, MS, USA?
You can take a train from Chicago Union Station to Picayune Amtrak Station via New Orleans Union Passenger Terminal in around 21h 57m. Alternatively, you can take a bus from Chicago Bus Station to Picayune via St Louis Bus Station and Slidell in around 23h 17m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Louis Armstrong New Orleans International Airport
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $130–650
Flights from Chicago Midway International Airport to Louis Armstrong New Orleans International Airport via Nashville
- Ave. Duration
- 3h 56m
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–650
Flights from Chicago Midway International Airport to Louis Armstrong New Orleans International Airport via Kansas City
- Ave. Duration
- 4h 15m
- When
- Sunday
- Estimated price
- $150–750
Flights from Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $140–800
Flights from Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport via Nashville
- Ave. Duration
- 3h 54m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $140–800
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $120–600
Flights from Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $130–600
Flights from Chicago Midway International Airport to Gulfport-Biloxi Regional Airport via Charlotte
- Ave. Duration
- 5h 17m
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–750
Flights from Chicago O'Hare International Airport to Louis Armstrong New Orleans International Airport
- Ave. Duration
- 2h 27m
- When
- Every day
- Estimated price
- $95–490
Flights from Chicago O'Hare International Airport to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $110–600
Flights from Chicago O'Hare International Airport to Birmingham–Shuttlesworth International Airport via Charlotte
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $150–750
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $100–500
Flights from Chicago Midway International Airport to Gulfport-Biloxi Regional Airport via Atlanta
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $140–700
Flights from Chicago Midway International Airport to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $160–850
Flights from Chicago O'Hare International Airport to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $120–650
- Website
- united.com
Flights from Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport via Houston
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $130–600
Flights from Chicago O'Hare International Airport to Louis Armstrong New Orleans International Airport
- Ave. Duration
- 2h 36m
- When
- Every day
- Estimated price
- $95–490
Flights from Chicago O'Hare International Airport to Birmingham–Shuttlesworth International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $110–600
- Website
- flybreeze.com
Flights from Chicago Midway International Airport to Gulfport-Biloxi Regional Airport via Orlando
- Ave. Duration
- 5h 45m
- When
- Sunday
- Estimated price
- $190–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to New Orleans Union Passenger Terminal
- Ave. Duration
- 19h 42m
- Frequency
- Once daily
- Estimated price
- $300–600
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Picayune Amtrak Station
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Picayune Amtrak Station
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.amtrak.com/home.html
Train from New Orleans Union Passenger Terminal to Picayune Amtrak Station
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 5h 55m
- Frequency
- Twice daily
- Estimated price
- $45–80
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Slidell
- Ave. Duration
- 16h
- Frequency
- Once daily
- Estimated price
- $100–190
- Website
- https://www.greyhound.com/
- Ave. Duration
- 1h 2m
- Estimated price
- $110–140
Gulf Coast Yellow Cab
- Phone
- +1-228-385-7777
Gulf Coast Yellow Cab
- Phone
- +1-228-385-7777
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More Questions & Answers
Chicago to Picayune bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Chicago to Picayune train services, operated by Amtrak, arrive at New Orleans Union Passenger Terminal station.
Yes, the driving distance between Chicago to Picayune is 892 miles. It takes approximately 14h 32m to drive from Chicago to Picayune.
Book your Chicago to Picayune train tickets online with Omio.
There are 13+ hotels available in Picayune.






