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How to get fromChicago to Nicholasvilleby plane, bus, car or train

Find Transport to Nicholasville

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There are 12 ways to get from Chicago to Nicholasville by plane, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Blue Grass Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    3h 30m
    $82–330

  2. Bus, drive (Amtrak)

    cheapest
    1. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    2. Drive from Oxmoor Center to Nicholasvillecar car
    10h
    $63–78

  3. Bus, drive via Indianapolis

    1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    3. Drive from Fern Valley @ Shepherdsville to Nicholasvillecar car
    9h 38m
    $71–121

  4. Train, bus, drive (Amtrak)

    1. Take the train from Chicago Union Station to Indianapolistrain train
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    3. Drive from Oxmoor Center to Nicholasvillecar car
    11h 23m
    $67–110

  5. Drive 370.2 mi

    1. Drive from Chicago to Nicholasvillecar car 370.2 mi
    6h 30m
    $68–98

  6. Fly Chicago Midway International Airport to Blue Grass Airport

    1. Fly from Chicago Midway International Airport (MDW) to Blue Grass Airport (LEX)plane plane MDW - LEX
    5h 54m
    $112–490

  7. Fly Chicago O'Hare International Airport to Covington, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Covington (CVG)plane plane ORD - CVG
    2. Drive from Covington (CVG) to Nicholasvillecar car
    4h 44m
    $94–579

  8. Fly Chicago O'Hare International Airport to Louisville International Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    2. Drive from Louisville-Airport-SDF to Nicholasvillecar car
    4h 45m
    $206–576

  9. Fly Chicago Midway International Airport to Louisville International Airport, drive

    1. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    2. Drive from Louisville-Airport-SDF to Nicholasvillecar car
    4h 19m
    $96–576

  10. Fly Chicago Midway International Airport to Covington, drive

    1. Fly from Chicago Midway International Airport (MDW) to Covington (CVG)plane plane MDW - CVG
    2. Drive from Covington (CVG) to Nicholasvillecar car
    4h 19m
    $118–779

  11. Bus, drive #2 (Amtrak)

    1. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    2. Drive from Fern Valley @ Shepherdsville to Nicholasvillecar car
    10h 8m
    $64–79

  12. Train, bus, drive via Newburg (Amtrak)

    1. Take the train from Chicago Union Station to Indianapolistrain train
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    3. Drive from Fern Valley @ Shepherdsville to Nicholasvillecar car
    11h 27m
    $68–111

Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX) flights

Calendar69Weekly Planes
Duration1h 29mAverage Duration
Ticket$41Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Nicholasville, KY, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX) every 3 hours.

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