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How to get fromChicago to Natickby plane, train, train (Amtrak), bus (Flixbus), car or bus

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There are 10 ways to get from Chicago to Natick by plane, train, train (Amtrak), bus (Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Boston Logan Airport, train

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Boston Logan Airport (BOS)plane plane ORD - BOS
    2. Take the train from Back Bay to Natick Centertrain train
    5h 52m
    $154–503

  2. Fly Chicago O'Hare International Airport to Theodore Francis Green State Airport, train

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Theodore Francis Green State Airport (PVD)plane plane ORD - PVD
    2. Take the train from TF Green Airport to Back Baytrain train
    7h 58m
    $80–360

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Framingham Amtraktrain train Lake Shore Limited
    22h 18m
    $274–601

  4. Bus (Flixbus)

    1. Take the bus from Chicago Bus Station to New York Midtownbus bus FlixBus N2641 / ...
    2. Take the bus from New York Midtown to Bostonbus bus FlixBus 2610 / ...
    24h
    $144–248

  5. Drive 964.9 mi

    1. Drive from Chicago to Natickcar car 964.9 mi
    16h 33m
    $177–255

  6. Fly Chicago Midway International Airport to Boston Logan Airport

    1. Fly from Chicago Midway International Airport (MDW) to Boston Logan Airport (BOS)plane plane MDW - BOS
    5h 35m
    $124–623

  7. Fly Chicago Midway International Airport to Manchester Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Manchester Airport (MHT)plane plane MDW - MHT
    2. Take the bus from Boston Manchester Airport to Bostonbus bus
    7h 26m
    $124–631

  8. Fly Chicago Midway International Airport to Theodore Francis Green State Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Theodore Francis Green State Airport (PVD)plane plane MDW - PVD
    2. Take the train from TF Green Airport to Back Baytrain train
    7h 31m
    $104–500

  9. Fly Chicago O'Hare International Airport to Manchester Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Manchester Airport (MHT)plane plane ORD - MHT
    2. Take the bus from Boston Manchester Airport to Bostonbus bus
    8h 5m
    $88–431

  10. Fly Chicago Midway International Airport to Bradley International Airport, bus, train

    1. Fly from Chicago Midway International Airport (MDW) to Bradley International Airport (BDL)plane plane MDW - BDL
    2. Take the bus from Hartford Union Station to Worcester Union Stationbus bus
    3. Take the train from Worcester to Natick Centertrain train
    8h 8m
    $130–698

Chicago to Natick by train (Amtrak)

Calendar7Weekly Trains
Duration22h 18mAverage Duration
Ticket$274Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Natick, MA, USA?

Amtrak operates a train from Chicago Union Station to Framingham Amtrak once daily. Tickets cost $270–600 and the journey takes 21h 28m. Alternatively, you can take a bus from Chicago Bus Station to Natick Center - South Ave opp Adams St via New York Midtown, Boston, and South Station - Bus Terminal Gate B1/B2 in around 24h.

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