Rome2Rio

How to get fromChicago to Natickby subway, plane, train, train (Amtrak), bus (Flixbus, Greyhound), car, or bus

Find Transport to Natick

See all options

There are 9 ways to get from Chicago to Natick by subway, plane, train, train (Amtrak), bus (Flixbus, Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Subway to Chicago Midway International Airport, fly to Boston Logan Airport, train

    best
    1. Take the subway from Adams/Wabash to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Boston Logan Airport (BOS)plane plane MDW - BOS
    3. Take the train from Back Bay to Natick Centertrain train
    5h 39m
    $134–673

  2. Fly Chicago O'Hare International Airport to Theodore Francis Green State Airport, train

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Theodore Francis Green State Airport (PVD)plane plane ORD - PVD
    2. Take the train from TF Green Airport to Back Baytrain train
    8h 5m
    $64–290

  3. Train (Amtrak)

    1. Take the train from Chicago Union Station to Framingham Amtraktrain train Lake Shore Limited
    22h 19m
    $551–851

  4. Bus

    1. Take the bus from Chicago Bus Station to Newark Penn Stationbus bus FlixBus N2640 / ...
    2. Take the bus from Newark Penn Station to Bostonbus bus Greyhound US0235 / ...
    27h 1m
    $190–299

  5. Drive  964.9 mi

    1. Drive from Chicago to Natickcar car 964.9 mi
    16h 33m
    $171–247

  6. Fly Chicago O'Hare International Airport to Boston Logan Airport, train

    1. Fly from Chicago O'Hare International Airport (ORD) to Boston Logan Airport (BOS)plane plane ORD - BOS
    2. Take the train from Back Bay to Natick Centertrain train
    5h 59m
    $564–1,023

  7. Fly Chicago Midway International Airport to Manchester Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Manchester Airport (MHT)plane plane MDW - MHT
    2. Take the bus from Boston Manchester Airport to Bostonbus bus
    7h 35m
    $114–579

  8. Fly Chicago Midway International Airport to Theodore Francis Green State Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Theodore Francis Green State Airport (PVD)plane plane MDW - PVD
    2. Take the train from TF Green Airport to Back Baytrain train
    7h 38m
    $94–450

  9. Fly Chicago Midway International Airport to Bradley International Airport, bus, train

    1. Fly from Chicago Midway International Airport (MDW) to Bradley International Airport (BDL)plane plane MDW - BDL
    2. Take the bus from Hartford to Worcesterbus bus
    3. Take the train from Worcester to Natick Centertrain train
    8h 16m
    $172–890

Chicago to Natick by train (Amtrak)

Calendar7Weekly Trains
Duration22h 19mAverage Duration
Ticket$551Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Chicago to Natick.ExpandLaunch map view
  • Distance: 895.5 mi
  • Duration: 5h 39m

What companies run services between Chicago, IL, USA and Natick, MA, USA?

Amtrak operates a train from Chicago Union Station to Framingham Amtrak once daily. Tickets cost $550–850 and the journey takes 21h 28m. Alternatively, you can take a bus from Chicago Bus Station to Natick Center - South Ave opp Adams St via Newark Penn Station, Boston, and South Station - Bus Terminal Gates 4-6 in around 27h 1m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There